Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3811

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
4,273,957	-		Rv3810	0.25	+1.1
4,273,957	-		Rv3810	0.25	-2.0
4,274,452	-		Rv3810	0.83	+2.1
4,274,591	+				-1.7
4,274,659	+				+2.1
4,274,660	-				-1.3
4,274,660	-				-0.3
4,274,667	+				+0.5
4,274,668	-				+0.4
4,274,677	+				-1.0
4,274,677	+				+0.6
4,274,677	+				-0.5
4,274,678	-				-0.9
4,274,678	-				-0.4
4,274,678	-				-1.2
4,274,678	-				-0.4
4,274,723	+				-0.4
4,274,744	+				+0.0
4,274,929	-				+2.1
4,274,990	-		Rv3811	0.12	-0.9
4,275,042	-		Rv3811	0.15	-0.4
4,275,054	-		Rv3811	0.16	-1.5
4,275,446	+		Rv3811	0.40	-0.3
4,275,447	-		Rv3811	0.40	-1.0
4,275,500	+		Rv3811	0.43	+3.1
4,275,539	+		Rv3811	0.46	-1.3
4,275,539	+		Rv3811	0.46	+2.1
4,275,539	+		Rv3811	0.46	-1.3
4,275,540	-		Rv3811	0.46	-1.4
4,275,540	-		Rv3811	0.46	+0.1
4,275,540	-		Rv3811	0.46	+1.1
4,275,540	-		Rv3811	0.46	-0.3
4,275,540	-		Rv3811	0.46	-0.3
4,275,546	-		Rv3811	0.46	-0.6
4,275,581	+		Rv3811	0.48	-0.3
4,275,602	+		Rv3811	0.50	-1.2
4,275,602	+		Rv3811	0.50	+2.5
4,275,602	+		Rv3811	0.50	-0.7
4,275,603	-		Rv3811	0.50	-1.0
4,275,603	-		Rv3811	0.50	+0.5
4,275,603	-		Rv3811	0.50	-1.3
4,275,603	-		Rv3811	0.50	+0.5
4,275,826	+		Rv3811	0.63	-0.7
4,275,834	-		Rv3811	0.64	+0.2
4,275,834	-		Rv3811	0.64	-1.5
4,275,858	+		Rv3811	0.65	-1.6
4,276,016	+		Rv3811	0.75	-0.7
4,276,130	+		Rv3811	0.82	-0.5
4,276,130	+		Rv3811	0.82	-0.8
4,276,131	-		Rv3811	0.82	-0.8
4,276,175	+		Rv3811	0.85	-0.1
4,276,175	+		Rv3811	0.85	+0.3
4,276,176	-		Rv3811	0.85	-1.8
4,276,200	-		Rv3811	0.87	-1.1
4,276,433	+				-0.0
4,276,442	+				-0.2
4,276,443	-				-0.6
4,276,443	-				-0.3
4,276,496	+				-2.2
4,276,496	+				-0.2
4,276,800	+		Rv3812	0.15	-3.0
4,276,801	-		Rv3812	0.15	-0.9
4,276,977	-		Rv3812	0.27	-0.7
4,277,162	+		Rv3812	0.39	-0.9
4,277,163	-		Rv3812	0.39	-0.9
4,277,176	+		Rv3812	0.40	+0.8
4,277,177	-		Rv3812	0.40	+0.1
4,277,280	+		Rv3812	0.47	+0.5
4,277,281	-		Rv3812	0.47	-1.6
4,277,410	+		Rv3812	0.55	-1.6
4,277,411	-		Rv3812	0.55	+0.9