Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3714c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3712 and Rv3713 are separated by 4 nucleotidesRv3713 and Rv3714c are separated by 8 nucleotidesRv3714c and Rv3715c are separated by 67 nucleotidesRv3715c and Rv3716c are separated by 11 nucleotides Rv3712: Rv3712 - Possible ligase, at 4,156,981 to 4,158,222 Rv3712 Rv3713: Rv3713 - Possible cobyric acid synthase CobQ2, at 4,158,227 to 4,158,922 Rv3713 Rv3714c: Rv3714c - Conserved hypothetical protein, at 4,158,931 to 4,159,821 Rv3714c Rv3715c: Rv3715c - Probable recombination protein RecR, at 4,159,889 to 4,160,500 Rv3715c Rv3716c: Rv3716c - Conserved protein, at 4,160,512 to 4,160,913 Rv3716c Position (kb) 4158 4159 4160Strain fitness (log2 ratio) -2 -1 0 1 2at 4158.920 kb on + strandat 4159.121 kb on + strand, within Rv3714cat 4159.122 kb on - strand, within Rv3714cat 4159.122 kb on - strand, within Rv3714cat 4159.122 kb on - strand, within Rv3714cat 4159.122 kb on - strand, within Rv3714cat 4159.324 kb on + strand, within Rv3714cat 4159.324 kb on + strand, within Rv3714cat 4159.325 kb on - strand, within Rv3714cat 4159.418 kb on + strand, within Rv3714cat 4159.496 kb on - strand, within Rv3714cat 4159.594 kb on - strand, within Rv3714cat 4159.600 kb on + strand, within Rv3714cat 4159.601 kb on - strand, within Rv3714cat 4159.679 kb on + strand, within Rv3714cat 4159.679 kb on + strand, within Rv3714cat 4159.680 kb on - strand, within Rv3714cat 4159.680 kb on - strand, within Rv3714cat 4159.680 kb on - strand, within Rv3714cat 4159.680 kb on - strand, within Rv3714cat 4160.029 kb on - strand, within Rv3715cat 4160.193 kb on + strand, within Rv3715cat 4160.399 kb on + strand, within Rv3715cat 4160.572 kb on - strand, within Rv3716c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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4,158,920 + +0.2
4,159,121 + Rv3714c 0.21 -0.2
4,159,122 - Rv3714c 0.21 -0.6
4,159,122 - Rv3714c 0.21 +0.1
4,159,122 - Rv3714c 0.21 -0.2
4,159,122 - Rv3714c 0.21 -1.5
4,159,324 + Rv3714c 0.44 -0.1
4,159,324 + Rv3714c 0.44 -0.9
4,159,325 - Rv3714c 0.44 -0.4
4,159,418 + Rv3714c 0.55 -0.8
4,159,496 - Rv3714c 0.63 +0.5
4,159,594 - Rv3714c 0.74 -0.4
4,159,600 + Rv3714c 0.75 +0.9
4,159,601 - Rv3714c 0.75 +0.1
4,159,679 + Rv3714c 0.84 +0.2
4,159,679 + Rv3714c 0.84 -0.0
4,159,680 - Rv3714c 0.84 +0.8
4,159,680 - Rv3714c 0.84 +1.8
4,159,680 - Rv3714c 0.84 -0.9
4,159,680 - Rv3714c 0.84 +1.1
4,160,029 - Rv3715c 0.23 -0.2
4,160,193 + Rv3715c 0.50 -1.8
4,160,399 + Rv3715c 0.83 +2.1
4,160,572 - Rv3716c 0.15 +0.2

Or see this region's nucleotide sequence