Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3427c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3426 and Rv3427c are separated by 150 nucleotidesRv3427c and Rv3428c are separated by 97 nucleotides Rv3426: Rv3426 - PPE family protein PPE58, at 3,843,036 to 3,843,734 Rv3426 Rv3427c: Rv3427c - Possible transposase, at 3,843,885 to 3,844,640 Rv3427c Rv3428c: Rv3428c - Possible transposase, at 3,844,738 to 3,845,970 Rv3428c Position (kb) 3843 3844 3845Strain fitness (log2 ratio) -2 -1 0 1 2at 3842.894 kb on + strandat 3842.894 kb on + strandat 3843.206 kb on + strand, within Rv3426at 3843.491 kb on - strand, within Rv3426at 3843.804 kb on + strandat 3843.805 kb on - strandat 3843.805 kb on - strandat 3843.829 kb on + strandat 3843.830 kb on - strandat 3843.856 kb on + strandat 3843.863 kb on + strandat 3843.886 kb on + strandat 3843.887 kb on - strandat 3844.455 kb on + strand, within Rv3427cat 3844.602 kb on - strandat 3844.606 kb on - strandat 3844.635 kb on - strandat 3845.360 kb on - strand, within Rv3428cat 3845.491 kb on - strand, within Rv3428c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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3,842,894 + -0.6
3,842,894 + -2.3
3,843,206 + Rv3426 0.24 -0.9
3,843,491 - Rv3426 0.65 +1.8
3,843,804 + +0.4
3,843,805 - +0.8
3,843,805 - -0.7
3,843,829 + -1.0
3,843,830 - -0.3
3,843,856 + -0.6
3,843,863 + -0.6
3,843,886 + -0.9
3,843,887 - -0.1
3,844,455 + Rv3427c 0.75 -1.0
3,844,602 - +0.5
3,844,606 - +1.1
3,844,635 - +0.4
3,845,360 - Rv3428c 0.50 -0.1
3,845,491 - Rv3428c 0.61 -0.1

Or see this region's nucleotide sequence