Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3414c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3412 and Rv3413c are separated by 9 nucleotidesRv3413c and Rv3414c overlap by 8 nucleotidesRv3414c and Rv3415c are separated by 17 nucleotides Rv3412: Rv3412 - Conserved hypothetical protein, at 3,831,726 to 3,832,136 Rv3412 Rv3413c: Rv3413c - Unknown alanine and proline rich protein, at 3,832,146 to 3,833,045 Rv3413c Rv3414c: Rv3414c - Probable alternative RNA polymerase sigma-D factor SigD, at 3,833,038 to 3,833,676 Rv3414c Rv3415c: Rv3415c - Conserved hypothetical protein, at 3,833,694 to 3,834,521 Rv3415c Position (kb) 3833 3834Strain fitness (log2 ratio) -1 0 1at 3832.484 kb on + strand, within Rv3413cat 3832.485 kb on - strand, within Rv3413cat 3833.045 kb on + strandat 3833.046 kb on - strandat 3833.310 kb on - strand, within Rv3414cat 3833.369 kb on + strand, within Rv3414cat 3833.422 kb on + strand, within Rv3414cat 3833.623 kb on + strandat 3833.658 kb on + strandat 3834.126 kb on + strand, within Rv3415cat 3834.126 kb on + strand, within Rv3415cat 3834.126 kb on + strand, within Rv3415cat 3834.126 kb on + strand, within Rv3415cat 3834.127 kb on - strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.296 kb on + strand, within Rv3415cat 3834.361 kb on + strand, within Rv3415cat 3834.438 kb on + strand, within Rv3415cat 3834.649 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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3,832,484 + Rv3413c 0.38 +1.0
3,832,485 - Rv3413c 0.38 -0.6
3,833,045 + +0.3
3,833,046 - +0.8
3,833,310 - Rv3414c 0.43 -0.9
3,833,369 + Rv3414c 0.52 -0.9
3,833,422 + Rv3414c 0.60 -1.2
3,833,623 + -1.5
3,833,658 + -1.0
3,834,126 + Rv3415c 0.52 -0.9
3,834,126 + Rv3415c 0.52 -1.2
3,834,126 + Rv3415c 0.52 -0.8
3,834,126 + Rv3415c 0.52 -0.7
3,834,127 - Rv3415c 0.52 +0.2
3,834,296 + Rv3415c 0.73 +0.4
3,834,296 + Rv3415c 0.73 -0.9
3,834,296 + Rv3415c 0.73 -0.5
3,834,296 + Rv3415c 0.73 -1.1
3,834,296 + Rv3415c 0.73 -0.2
3,834,296 + Rv3415c 0.73 -0.2
3,834,296 + Rv3415c 0.73 -1.5
3,834,296 + Rv3415c 0.73 -0.7
3,834,361 + Rv3415c 0.81 -0.7
3,834,438 + Rv3415c 0.90 +0.0
3,834,649 + -1.2

Or see this region's nucleotide sequence