Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3387

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3385c and Rv3386 are separated by 148 nucleotidesRv3386 and Rv3387 overlap by 11 nucleotidesRv3387 and Rv3388 are separated by 189 nucleotides Rv3385c: Rv3385c - Possible antitoxin VapB46, at 3,799,635 to 3,799,943 Rv3385c Rv3386: Rv3386 - Possible transposase, at 3,800,092 to 3,800,796 Rv3386 Rv3387: Rv3387 - Possible transposase, at 3,800,786 to 3,801,463 Rv3387 Rv3388: Rv3388 - PE-PGRS family protein PE_PGRS52, at 3,801,653 to 3,803,848 Rv3388 Position (kb) 3800 3801 3802Strain fitness (log2 ratio) -1 0 1at 3799.988 kb on - strandat 3800.314 kb on + strand, within Rv3386at 3800.794 kb on + strandat 3801.356 kb on + strand, within Rv3387at 3801.356 kb on + strand, within Rv3387at 3801.546 kb on + strandat 3801.546 kb on + strandat 3801.546 kb on + strandat 3801.547 kb on - strandat 3801.547 kb on - strandat 3801.547 kb on - strandat 3801.549 kb on + strandat 3801.550 kb on + strandat 3801.550 kb on - strandat 3801.550 kb on - strandat 3801.550 kb on - strandat 3801.553 kb on + strandat 3801.837 kb on - strandat 3801.911 kb on + strand, within Rv3388at 3801.912 kb on - strand, within Rv3388at 3802.208 kb on + strand, within Rv3388at 3802.209 kb on - strand, within Rv3388at 3802.399 kb on + strand, within Rv3388at 3802.399 kb on + strand, within Rv3388

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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3,799,988 - -0.2
3,800,314 + Rv3386 0.31 -0.8
3,800,794 + -0.1
3,801,356 + Rv3387 0.84 -0.9
3,801,356 + Rv3387 0.84 +1.0
3,801,546 + +0.3
3,801,546 + +0.1
3,801,546 + +0.6
3,801,547 - -1.1
3,801,547 - -0.8
3,801,547 - +0.7
3,801,549 + +1.4
3,801,550 + +0.1
3,801,550 - +0.4
3,801,550 - -0.2
3,801,550 - -0.8
3,801,553 + -0.4
3,801,837 - -0.4
3,801,911 + Rv3388 0.12 -0.2
3,801,912 - Rv3388 0.12 -0.2
3,802,208 + Rv3388 0.25 +0.2
3,802,209 - Rv3388 0.25 +1.1
3,802,399 + Rv3388 0.34 +1.0
3,802,399 + Rv3388 0.34 +0.5

Or see this region's nucleotide sequence