Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2663

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2660c and Rv2661c overlap by 4 nucleotidesRv2661c and Rv2662 overlap by 95 nucleotidesRv2662 and Rv2663 are separated by 98 nucleotidesRv2663 and Rv2664 are separated by 10 nucleotidesRv2664 and Rv2665 are separated by 347 nucleotidesRv2665 and Rv2666 are separated by 90 nucleotides Rv2660c: Rv2660c - Hypothetical protein, at 2,980,963 to 2,981,190 Rv2660c Rv2661c: Rv2661c - Hypothetical protein, at 2,981,187 to 2,981,576 Rv2661c Rv2662: Rv2662 - Hypothetical protein, at 2,981,482 to 2,981,754 Rv2662 Rv2663: Rv2663 - Hypothetical protein, at 2,981,853 to 2,982,086 Rv2663 Rv2664: Rv2664 - Hypothetical protein, at 2,982,097 to 2,982,351 Rv2664 Rv2665: Rv2665 - Hypothetical arginine rich protein, at 2,982,699 to 2,982,980 Rv2665 Rv2666: Rv2666 - Probable transposase for insertion sequence element IS1081 (fragment), at 2,983,071 to 2,983,874 Rv2666 Position (kb) 2981 2982 2983Strain fitness (log2 ratio) -1 0 1 2 3 4at 2981.043 kb on + strand, within Rv2660cat 2981.044 kb on - strand, within Rv2660cat 2981.044 kb on - strand, within Rv2660cat 2981.044 kb on - strand, within Rv2660cat 2981.416 kb on - strand, within Rv2661cat 2981.466 kb on - strand, within Rv2661cat 2981.584 kb on + strand, within Rv2662at 2981.585 kb on - strand, within Rv2662at 2981.627 kb on + strand, within Rv2662at 2981.808 kb on + strandat 2981.809 kb on - strandat 2981.809 kb on - strandat 2981.809 kb on - strandat 2981.809 kb on - strandat 2981.946 kb on + strand, within Rv2663at 2981.947 kb on - strand, within Rv2663at 2981.947 kb on - strand, within Rv2663at 2982.001 kb on + strand, within Rv2663at 2982.002 kb on - strand, within Rv2663at 2982.052 kb on + strand, within Rv2663at 2982.053 kb on - strand, within Rv2663at 2982.053 kb on - strand, within Rv2663at 2982.055 kb on + strand, within Rv2663at 2982.056 kb on - strand, within Rv2663at 2982.069 kb on + strandat 2982.069 kb on + strandat 2982.070 kb on - strandat 2982.092 kb on + strandat 2982.092 kb on + strandat 2982.508 kb on - strandat 2982.581 kb on + strandat 2982.581 kb on + strandat 2982.582 kb on - strandat 2982.661 kb on + strandat 2982.662 kb on - strandat 2982.662 kb on - strandat 2982.914 kb on - strand, within Rv2665at 2982.969 kb on - strandat 2982.979 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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2,981,043 + Rv2660c 0.35 +0.2
2,981,044 - Rv2660c 0.36 +0.0
2,981,044 - Rv2660c 0.36 +1.3
2,981,044 - Rv2660c 0.36 -0.3
2,981,416 - Rv2661c 0.59 -0.8
2,981,466 - Rv2661c 0.72 +0.7
2,981,584 + Rv2662 0.37 -0.6
2,981,585 - Rv2662 0.38 +2.5
2,981,627 + Rv2662 0.53 +1.0
2,981,808 + +0.1
2,981,809 - -0.5
2,981,809 - -0.2
2,981,809 - +0.8
2,981,809 - -0.7
2,981,946 + Rv2663 0.40 -0.9
2,981,947 - Rv2663 0.40 -0.7
2,981,947 - Rv2663 0.40 -0.0
2,982,001 + Rv2663 0.63 +0.7
2,982,002 - Rv2663 0.64 +0.3
2,982,052 + Rv2663 0.85 +0.7
2,982,053 - Rv2663 0.85 +0.7
2,982,053 - Rv2663 0.85 +1.3
2,982,055 + Rv2663 0.86 -1.4
2,982,056 - Rv2663 0.87 +1.3
2,982,069 + +1.7
2,982,069 + -0.7
2,982,070 - -0.9
2,982,092 + -1.0
2,982,092 + +2.7
2,982,508 - -0.4
2,982,581 + +3.9
2,982,581 + -0.1
2,982,582 - +1.7
2,982,661 + -0.3
2,982,662 - +2.9
2,982,662 - -1.1
2,982,914 - Rv2665 0.76 +0.1
2,982,969 - +0.3
2,982,979 - -1.4

Or see this region's nucleotide sequence