Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1873

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
2,122,668	+		Rv1872c	0.61	+0.0
2,122,668	+		Rv1872c	0.61	-1.2
2,122,669	-		Rv1872c	0.61	+0.8
2,122,669	-		Rv1872c	0.61	+0.5
2,122,669	-		Rv1872c	0.61	-0.6
2,122,669	-		Rv1872c	0.61	+2.5
2,122,669	-		Rv1872c	0.61	-0.1
2,122,669	-		Rv1872c	0.61	+0.9
2,122,670	+		Rv1872c	0.61	+2.1
2,122,670	+		Rv1872c	0.61	+0.5
2,122,671	-		Rv1872c	0.61	-0.2
2,122,671	-		Rv1872c	0.61	-0.8
2,122,671	-		Rv1872c	0.61	+1.5
2,122,671	-		Rv1872c	0.61	+0.1
2,122,671	-		Rv1872c	0.61	-0.7
2,122,671	-		Rv1872c	0.61	-0.7
2,123,005	-		Rv1872c	0.88	-0.6
2,123,157	+				-0.3
2,123,161	+				+0.4
2,123,173	+				+0.5
2,123,173	+				+0.9
2,123,174	-				-0.1
2,123,174	-				+0.7
2,123,317	-		Rv1873	0.33	+0.2
2,123,320	+		Rv1873	0.33	-0.7
2,123,320	+		Rv1873	0.33	-0.5
2,123,320	+		Rv1873	0.33	-1.2
2,123,320	+		Rv1873	0.33	-2.1
2,123,320	+		Rv1873	0.33	-0.4
2,123,321	-		Rv1873	0.34	-1.4
2,123,321	-		Rv1873	0.34	+0.3
2,123,321	-		Rv1873	0.34	+0.1
2,123,321	-		Rv1873	0.34	-0.4
2,123,323	+		Rv1873	0.34	-0.5
2,123,324	-		Rv1873	0.34	-1.3
2,123,375	+		Rv1873	0.46	+1.5
2,123,375	+		Rv1873	0.46	+0.8
2,123,558	+		Rv1873	0.88	+0.5
2,123,559	-		Rv1873	0.88	+0.6
2,123,595	+				-0.3
2,123,609	+				-1.3
2,123,609	+				-0.3
2,123,609	+				+0.7
2,123,609	+				-1.0
2,123,610	-				-0.1
2,123,610	-				-0.2
2,123,653	+				-1.1
2,123,653	+				-0.7
2,123,653	+				-0.8
2,123,654	-				-0.7
2,123,797	+		Rv1874	0.16	-0.1
2,123,798	-		Rv1874	0.17	+0.1
2,123,834	+		Rv1874	0.22	-0.1
2,123,834	+		Rv1874	0.22	-0.0
2,123,835	-		Rv1874	0.22	+0.5
2,123,835	-		Rv1874	0.22	-1.4
2,123,879	+		Rv1874	0.28	-0.5
2,123,880	-		Rv1874	0.29	+0.3
2,123,892	+		Rv1874	0.30	+0.2
2,123,893	-		Rv1874	0.30	-1.1
2,123,893	-		Rv1874	0.30	-0.7
2,123,893	-		Rv1874	0.30	+0.5
2,123,910	+		Rv1874	0.33	+2.5
2,123,910	+		Rv1874	0.33	-1.3
2,123,942	+		Rv1874	0.38	+0.5
2,123,943	-		Rv1874	0.38	+0.6
2,123,943	-		Rv1874	0.38	-3.6
2,123,943	-		Rv1874	0.38	-0.8
2,124,126	-		Rv1874	0.64	-0.9
2,124,341	+				+0.7
2,124,540	+		Rv1875	0.36	-1.9
2,124,540	+		Rv1875	0.36	-1.1
2,124,541	-		Rv1875	0.36	-1.5
2,124,567	-		Rv1875	0.42	-0.3