Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1476

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1475c and Rv1476 are separated by 157 nucleotidesRv1476 and Rv1477 are separated by 225 nucleotides Rv1475c: Rv1475c - Probable iron-regulated aconitate hydratase Acn (citrate hydro-lyase) (aconitase), at 1,663,215 to 1,666,046 Rv1475c Rv1476: Rv1476 - Possible membrane protein, at 1,666,204 to 1,666,764 Rv1476 Rv1477: Rv1477 - Peptidoglycan hydrolase, at 1,666,990 to 1,668,408 Rv1477 Position (kb) 1666 1667Strain fitness (log2 ratio) -4 -3 -2 -1 0 1at 1666.170 kb on - strandat 1666.180 kb on + strandat 1666.860 kb on + strandat 1666.909 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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1,666,170 - -0.6
1,666,180 + -1.3
1,666,860 + -1.1
1,666,909 - -3.9

Or see this region's nucleotide sequence