Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1189 and Rv1190 are separated by 15 nucleotides Rv1190 and Rv1191 are separated by 72 nucleotides Rv1191 and Rv1192 are separated by 81 nucleotides Rv1192 and Rv1193 are separated by 39 nucleotides
Rv1189: Rv1189 - Possible alternative RNA polymerase sigma factor SigI, at 1,332,092 to 1,332,964
Rv1189
Rv1190: Rv1190 - Conserved hypothetical protein, at 1,332,980 to 1,333,858
Rv1190
Rv1191: Rv1191 - Conserved protein, at 1,333,931 to 1,334,845
Rv1191
Rv1192: Rv1192 - Unknown protein, at 1,334,927 to 1,335,754
Rv1192
Rv1193: Rv1193 - Probable fatty-acid-CoA ligase FadD36 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 1,335,794 to 1,337,215
Rv1193
Position (kb)
1333
1334
1335 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 1333.297 kb on - strand, within Rv1190 at 1333.605 kb on - strand, within Rv1190 at 1333.605 kb on - strand, within Rv1190 at 1333.637 kb on + strand, within Rv1190 at 1333.637 kb on + strand, within Rv1190 at 1333.638 kb on - strand, within Rv1190 at 1333.924 kb on - strand at 1334.093 kb on + strand, within Rv1191 at 1334.110 kb on + strand, within Rv1191 at 1334.264 kb on + strand, within Rv1191 at 1334.264 kb on + strand, within Rv1191 at 1334.264 kb on + strand, within Rv1191 at 1334.264 kb on + strand, within Rv1191 at 1334.265 kb on - strand, within Rv1191 at 1334.265 kb on - strand, within Rv1191 at 1334.265 kb on - strand, within Rv1191 at 1334.486 kb on + strand, within Rv1191 at 1334.907 kb on - strand at 1334.918 kb on + strand at 1334.918 kb on + strand at 1334.919 kb on - strand at 1334.919 kb on - strand at 1334.921 kb on + strand at 1334.921 kb on + strand at 1334.922 kb on - strand at 1334.922 kb on - strand at 1334.922 kb on - strand at 1334.943 kb on + strand at 1334.987 kb on + strand at 1334.988 kb on - strand at 1334.988 kb on - strand at 1335.021 kb on - strand, within Rv1192 at 1335.094 kb on - strand, within Rv1192 at 1335.497 kb on + strand, within Rv1192 at 1335.709 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 1,333,297 - Rv1190 0.36 -0.6 1,333,605 - Rv1190 0.71 +0.1 1,333,605 - Rv1190 0.71 -2.3 1,333,637 + Rv1190 0.75 +0.3 1,333,637 + Rv1190 0.75 +2.1 1,333,638 - Rv1190 0.75 +0.1 1,333,924 - -1.1 1,334,093 + Rv1191 0.18 +2.3 1,334,110 + Rv1191 0.20 -1.3 1,334,264 + Rv1191 0.36 +0.1 1,334,264 + Rv1191 0.36 +0.7 1,334,264 + Rv1191 0.36 -0.0 1,334,264 + Rv1191 0.36 -1.4 1,334,265 - Rv1191 0.37 -1.3 1,334,265 - Rv1191 0.37 +3.3 1,334,265 - Rv1191 0.37 -3.7 1,334,486 + Rv1191 0.61 -0.9 1,334,907 - -0.5 1,334,918 + -0.4 1,334,918 + -0.5 1,334,919 - -0.9 1,334,919 - +1.7 1,334,921 + +0.3 1,334,921 + -0.5 1,334,922 - -0.4 1,334,922 - -0.4 1,334,922 - -0.1 1,334,943 + -1.5 1,334,987 + +1.0 1,334,988 - -0.5 1,334,988 - -0.3 1,335,021 - Rv1192 0.11 +0.0 1,335,094 - Rv1192 0.20 -2.3 1,335,497 + Rv1192 0.69 -0.1 1,335,709 + -0.6
Or see this region's nucleotide sequence