Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1034c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1032c and Rv1033c are separated by 7 nucleotidesRv1033c and Rv1034c are separated by 181 nucleotidesRv1034c and Rv1035c are separated by 67 nucleotidesRv1035c and Rv1036c are separated by 33 nucleotides Rv1032c: Rv1032c - Two component sensor histidine kinase TrcS, at 1,156,426 to 1,157,955 Rv1032c Rv1033c: Rv1033c - Two component transcriptional regulator TrcR, at 1,157,963 to 1,158,736 Rv1033c Rv1034c: Rv1034c - Probable transposase (fragment), at 1,158,918 to 1,159,307 Rv1034c Rv1035c: Rv1035c - Probable transposase (fragment), at 1,159,375 to 1,160,061 Rv1035c Rv1036c: Rv1036c - Probable IS1560 transposase (fragment), at 1,160,095 to 1,160,433 Rv1036c Position (kb) 1158 1159 1160Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.986 kb on - strandat 1157.986 kb on - strandat 1157.986 kb on - strandat 1158.005 kb on - strandat 1158.048 kb on + strand, within Rv1033cat 1158.049 kb on - strand, within Rv1033cat 1158.056 kb on - strand, within Rv1033cat 1158.056 kb on - strand, within Rv1033cat 1158.056 kb on - strand, within Rv1033cat 1158.057 kb on + strand, within Rv1033cat 1158.057 kb on + strand, within Rv1033cat 1158.058 kb on - strand, within Rv1033cat 1158.058 kb on - strand, within Rv1033cat 1158.058 kb on - strand, within Rv1033cat 1158.093 kb on + strand, within Rv1033cat 1158.094 kb on - strand, within Rv1033cat 1158.200 kb on - strand, within Rv1033cat 1158.213 kb on - strand, within Rv1033cat 1158.238 kb on + strand, within Rv1033cat 1158.239 kb on - strand, within Rv1033cat 1158.239 kb on - strand, within Rv1033cat 1158.239 kb on - strand, within Rv1033cat 1158.351 kb on + strand, within Rv1033cat 1158.351 kb on + strand, within Rv1033cat 1158.351 kb on + strand, within Rv1033cat 1158.429 kb on + strand, within Rv1033cat 1158.579 kb on + strand, within Rv1033cat 1158.580 kb on - strand, within Rv1033cat 1158.718 kb on - strandat 1158.745 kb on - strandat 1158.745 kb on - strandat 1158.813 kb on + strandat 1158.896 kb on + strandat 1159.516 kb on + strand, within Rv1035cat 1159.902 kb on - strand, within Rv1035cat 1160.177 kb on + strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036cat 1160.178 kb on - strand, within Rv1036c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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1,157,985 + -1.8
1,157,985 + -0.5
1,157,985 + -0.5
1,157,985 + -0.2
1,157,985 + -0.0
1,157,986 - -0.3
1,157,986 - -2.2
1,157,986 - -0.9
1,158,005 - +3.3
1,158,048 + Rv1033c 0.11 +0.7
1,158,049 - Rv1033c 0.11 +2.3
1,158,056 - Rv1033c 0.12 +2.3
1,158,056 - Rv1033c 0.12 -0.5
1,158,056 - Rv1033c 0.12 +1.1
1,158,057 + Rv1033c 0.12 -0.4
1,158,057 + Rv1033c 0.12 -0.4
1,158,058 - Rv1033c 0.12 +2.9
1,158,058 - Rv1033c 0.12 -1.1
1,158,058 - Rv1033c 0.12 -0.2
1,158,093 + Rv1033c 0.17 -0.4
1,158,094 - Rv1033c 0.17 -0.4
1,158,200 - Rv1033c 0.31 +0.8
1,158,213 - Rv1033c 0.32 -0.7
1,158,238 + Rv1033c 0.36 +1.3
1,158,239 - Rv1033c 0.36 -1.9
1,158,239 - Rv1033c 0.36 -0.5
1,158,239 - Rv1033c 0.36 -0.5
1,158,351 + Rv1033c 0.50 +1.3
1,158,351 + Rv1033c 0.50 -1.0
1,158,351 + Rv1033c 0.50 -0.5
1,158,429 + Rv1033c 0.60 -1.6
1,158,579 + Rv1033c 0.80 -0.4
1,158,580 - Rv1033c 0.80 -1.6
1,158,718 - -0.8
1,158,745 - -0.7
1,158,745 - -1.3
1,158,813 + -0.7
1,158,896 + -0.2
1,159,516 + Rv1035c 0.21 -0.9
1,159,902 - Rv1035c 0.77 -0.9
1,160,177 + Rv1036c 0.24 +0.7
1,160,178 - Rv1036c 0.24 -0.4
1,160,178 - Rv1036c 0.24 -1.1
1,160,178 - Rv1036c 0.24 -0.2
1,160,178 - Rv1036c 0.24 -0.7

Or see this region's nucleotide sequence