Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1002c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1001 and Rv1002c are separated by 34 nucleotidesRv1002c and Rv1003 are separated by 82 nucleotidesRv1003 and Rv1004c are separated by 9 nucleotides Rv1001: Rv1001 - Probable arginine deiminase ArcA (adi) (ad) (arginine dihydrolase), at 1,117,185 to 1,118,393 Rv1001 Rv1002c: Rv1002c - Conserved membrane protein, at 1,118,428 to 1,119,939 Rv1002c Rv1003: Rv1003 - Conserved protein, at 1,120,022 to 1,120,879 Rv1003 Rv1004c: Rv1004c - Probable membrane protein, at 1,120,889 to 1,122,148 Rv1004c Position (kb) 1118 1119 1120Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1117.515 kb on - strand, within Rv1001at 1117.613 kb on + strand, within Rv1001at 1117.721 kb on - strand, within Rv1001at 1117.761 kb on + strand, within Rv1001at 1117.761 kb on + strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.800 kb on + strand, within Rv1001at 1118.021 kb on + strand, within Rv1001at 1118.022 kb on - strand, within Rv1001at 1118.269 kb on + strand, within Rv1001at 1118.270 kb on - strand, within Rv1001at 1118.270 kb on - strand, within Rv1001at 1118.392 kb on - strandat 1120.009 kb on + strandat 1120.010 kb on - strandat 1120.360 kb on - strand, within Rv1003at 1120.878 kb on - strandat 1120.878 kb on - strandat 1120.890 kb on + strandat 1120.897 kb on + strandat 1120.897 kb on + strandat 1120.897 kb on + strandat 1120.898 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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1,117,515 - Rv1001 0.27 +3.3
1,117,613 + Rv1001 0.35 -0.6
1,117,721 - Rv1001 0.44 +0.2
1,117,761 + Rv1001 0.48 +0.4
1,117,761 + Rv1001 0.48 +0.2
1,117,762 - Rv1001 0.48 +0.3
1,117,762 - Rv1001 0.48 +2.3
1,117,762 - Rv1001 0.48 -1.1
1,117,762 - Rv1001 0.48 +1.1
1,117,762 - Rv1001 0.48 -1.0
1,117,800 + Rv1001 0.51 +0.4
1,118,021 + Rv1001 0.69 -0.5
1,118,022 - Rv1001 0.69 -0.3
1,118,269 + Rv1001 0.90 -0.8
1,118,270 - Rv1001 0.90 -1.0
1,118,270 - Rv1001 0.90 -0.5
1,118,392 - -1.3
1,120,009 + -2.2
1,120,010 - -1.2
1,120,360 - Rv1003 0.39 -1.3
1,120,878 - -1.1
1,120,878 - +0.7
1,120,890 + -0.9
1,120,897 + -1.0
1,120,897 + +0.3
1,120,897 + -0.3
1,120,898 - +0.5

Or see this region's nucleotide sequence