Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0957 and Rv0958 are separated by 106 nucleotides Rv0958 and Rv0959 overlap by 8 nucleotides
Rv0957: Rv0957 - Probable bifunctional purine biosynthesis protein PurH: phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) (5'-phosphoribosyl-5-aminoimidazole-4-carboxamide formyltransferase) + inosinemonophosphate cyclohydrolase (imp cyclohydrolase) (inosinicase) (imp synthetase) (ATIC), at 1,068,205 to 1,069,776
Rv0957
Rv0958: Rv0958 - Possible magnesium chelatase, at 1,069,883 to 1,071,262
Rv0958
Rv0959: Rv0959 - Conserved hypothetical protein, at 1,071,255 to 1,073,273
Rv0959
Position (kb)
1069
1070
1071
1072 Strain fitness (log2 ratio)
-1
0
1
2 at 1069.869 kb on - strand at 1069.894 kb on + strand at 1069.894 kb on + strand at 1070.192 kb on + strand, within Rv0958 at 1070.193 kb on - strand, within Rv0958 at 1070.248 kb on - strand, within Rv0958 at 1070.248 kb on - strand, within Rv0958 at 1070.279 kb on + strand, within Rv0958 at 1070.570 kb on + strand, within Rv0958 at 1070.570 kb on + strand, within Rv0958 at 1070.708 kb on + strand, within Rv0958 at 1071.205 kb on - strand at 1071.206 kb on + strand at 1071.207 kb on - strand at 1071.260 kb on + strand at 1071.328 kb on + strand at 1071.328 kb on + strand at 1071.329 kb on - strand at 1071.333 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 1,069,869 - +0.5 1,069,894 + +0.2 1,069,894 + -0.7 1,070,192 + Rv0958 0.22 +0.1 1,070,193 - Rv0958 0.22 -0.4 1,070,248 - Rv0958 0.26 +0.2 1,070,248 - Rv0958 0.26 +0.8 1,070,279 + Rv0958 0.29 -0.5 1,070,570 + Rv0958 0.50 -0.9 1,070,570 + Rv0958 0.50 -1.5 1,070,708 + Rv0958 0.60 +1.0 1,071,205 - +2.2 1,071,206 + -0.5 1,071,207 - -0.7 1,071,260 + -1.0 1,071,328 + -0.0 1,071,328 + -1.1 1,071,329 - +0.2 1,071,333 + -0.9
Or see this region's nucleotide sequence