Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0753c and Rv0754 are separated by 205 nucleotides Rv0754 and Rv0755c are separated by 189 nucleotides
Rv0753c: Rv0753c - Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH), at 844,421 to 845,953
Rv0753c
Rv0754: Rv0754 - PE-PGRS family protein PE_PGRS11, at 846,159 to 847,913
Rv0754
Rv0755c: Rv0755c - PPE family protein PPE12, at 848,103 to 850,040
Rv0755c
Position (kb)
846
847
848 Strain fitness (log2 ratio)
-1
0
1
2
3 at 845.250 kb on + strand, within Rv0753c at 845.257 kb on - strand, within Rv0753c at 845.257 kb on - strand, within Rv0753c at 845.550 kb on + strand, within Rv0753c at 845.551 kb on - strand, within Rv0753c at 845.583 kb on + strand, within Rv0753c at 846.054 kb on + strand at 846.131 kb on - strand at 846.133 kb on + strand at 846.133 kb on + strand at 846.133 kb on + strand at 846.153 kb on + strand at 846.298 kb on + strand at 846.417 kb on + strand, within Rv0754 at 846.417 kb on + strand, within Rv0754 at 846.417 kb on + strand, within Rv0754 at 846.417 kb on + strand, within Rv0754 at 846.417 kb on + strand, within Rv0754 at 846.418 kb on - strand, within Rv0754 at 846.418 kb on - strand, within Rv0754 at 846.418 kb on - strand, within Rv0754 at 846.511 kb on - strand, within Rv0754 at 847.150 kb on - strand, within Rv0754 at 847.234 kb on + strand, within Rv0754 at 847.308 kb on + strand, within Rv0754 at 847.308 kb on + strand, within Rv0754 at 847.308 kb on + strand, within Rv0754 at 847.309 kb on - strand, within Rv0754 at 847.309 kb on - strand, within Rv0754 at 847.409 kb on + strand, within Rv0754 at 847.431 kb on + strand, within Rv0754 at 847.431 kb on + strand, within Rv0754 at 847.491 kb on + strand, within Rv0754 at 847.491 kb on + strand, within Rv0754 at 847.491 kb on + strand, within Rv0754 at 847.598 kb on - strand, within Rv0754 at 847.725 kb on + strand, within Rv0754 at 847.725 kb on + strand, within Rv0754 at 847.869 kb on + strand at 847.870 kb on - strand at 847.873 kb on + strand at 847.873 kb on + strand at 847.874 kb on - strand at 847.874 kb on - strand at 847.874 kb on - strand at 847.928 kb on + strand at 847.928 kb on + strand at 847.928 kb on + strand at 847.929 kb on - strand at 847.929 kb on - strand at 847.929 kb on - strand at 848.094 kb on + strand at 848.095 kb on - strand at 848.100 kb on + strand at 848.142 kb on - strand at 848.820 kb on + strand, within Rv0755c at 848.820 kb on + strand, within Rv0755c at 848.820 kb on + strand, within Rv0755c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 845,250 + Rv0753c 0.54 -0.6 845,257 - Rv0753c 0.55 -0.4 845,257 - Rv0753c 0.55 -0.4 845,550 + Rv0753c 0.74 -0.4 845,551 - Rv0753c 0.74 -0.8 845,583 + Rv0753c 0.76 -0.1 846,054 + -1.2 846,131 - -0.7 846,133 + -0.6 846,133 + -0.4 846,133 + +0.1 846,153 + +1.5 846,298 + +1.2 846,417 + Rv0754 0.15 +0.7 846,417 + Rv0754 0.15 -0.0 846,417 + Rv0754 0.15 -0.8 846,417 + Rv0754 0.15 -0.2 846,417 + Rv0754 0.15 +0.1 846,418 - Rv0754 0.15 +0.6 846,418 - Rv0754 0.15 +1.2 846,418 - Rv0754 0.15 +1.0 846,511 - Rv0754 0.20 -0.0 847,150 - Rv0754 0.56 +1.2 847,234 + Rv0754 0.61 +0.6 847,308 + Rv0754 0.65 -0.4 847,308 + Rv0754 0.65 -1.0 847,308 + Rv0754 0.65 +2.2 847,309 - Rv0754 0.66 -0.1 847,309 - Rv0754 0.66 -0.4 847,409 + Rv0754 0.71 -0.6 847,431 + Rv0754 0.72 +1.8 847,431 + Rv0754 0.72 -1.0 847,491 + Rv0754 0.76 -1.1 847,491 + Rv0754 0.76 -0.8 847,491 + Rv0754 0.76 +0.4 847,598 - Rv0754 0.82 +0.7 847,725 + Rv0754 0.89 +0.3 847,725 + Rv0754 0.89 +1.2 847,869 + +0.5 847,870 - -0.4 847,873 + +0.4 847,873 + +3.2 847,874 - -1.5 847,874 - -0.4 847,874 - +3.2 847,928 + +0.6 847,928 + -0.3 847,928 + +0.2 847,929 - -0.2 847,929 - +2.2 847,929 - -1.3 848,094 + -0.1 848,095 - -0.9 848,100 + -0.1 848,142 - -0.8 848,820 + Rv0755c 0.37 +0.6 848,820 + Rv0755c 0.37 -0.5 848,820 + Rv0755c 0.37 +0.2
Or see this region's nucleotide sequence