Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0595c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0594 and Rv0595c are separated by 51 nucleotidesRv0595c and Rv0596c overlap by 4 nucleotidesRv0596c and Rv0597c are separated by 182 nucleotides Rv0594: Rv0594 - Mce-family protein Mce2F, at 693,237 to 694,787 Rv0594 Rv0595c: Rv0595c - Possible toxin VapC4, at 694,839 to 695,231 Rv0595c Rv0596c: Rv0596c - Possible antitoxin VapB4, at 695,228 to 695,485 Rv0596c Rv0597c: Rv0597c - Conserved hypothetical protein, at 695,668 to 696,903 Rv0597c Position (kb) 694 695 696Strain fitness (log2 ratio) -2 -1 0 1 2 3at 694.133 kb on + strand, within Rv0594at 694.136 kb on + strand, within Rv0594at 694.137 kb on - strand, within Rv0594at 694.279 kb on - strand, within Rv0594at 694.339 kb on + strand, within Rv0594at 694.340 kb on - strand, within Rv0594at 694.395 kb on + strand, within Rv0594at 694.395 kb on + strand, within Rv0594at 694.395 kb on + strand, within Rv0594at 694.396 kb on - strand, within Rv0594at 694.645 kb on - strandat 694.645 kb on - strandat 694.664 kb on + strandat 694.664 kb on + strandat 694.665 kb on - strandat 694.665 kb on - strandat 694.665 kb on - strandat 694.665 kb on - strandat 694.665 kb on - strandat 694.675 kb on - strandat 694.700 kb on - strandat 694.700 kb on - strandat 694.700 kb on - strandat 694.700 kb on - strandat 694.720 kb on - strandat 694.848 kb on + strandat 694.986 kb on + strand, within Rv0595cat 694.986 kb on + strand, within Rv0595cat 695.022 kb on + strand, within Rv0595cat 695.050 kb on + strand, within Rv0595cat 695.051 kb on - strand, within Rv0595cat 695.223 kb on + strandat 695.223 kb on + strandat 695.556 kb on - strandat 695.789 kb on + strandat 695.789 kb on + strandat 695.794 kb on + strand, within Rv0597cat 695.794 kb on + strand, within Rv0597cat 695.794 kb on + strand, within Rv0597cat 695.984 kb on - strand, within Rv0597c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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694,133 + Rv0594 0.58 +2.2
694,136 + Rv0594 0.58 -0.3
694,137 - Rv0594 0.58 +1.2
694,279 - Rv0594 0.67 +0.9
694,339 + Rv0594 0.71 -1.2
694,340 - Rv0594 0.71 -1.3
694,395 + Rv0594 0.75 -0.4
694,395 + Rv0594 0.75 -2.5
694,395 + Rv0594 0.75 +1.4
694,396 - Rv0594 0.75 +0.3
694,645 - -1.4
694,645 - -0.4
694,664 + -1.4
694,664 + +0.2
694,665 - +0.8
694,665 - +0.9
694,665 - -0.4
694,665 - -1.2
694,665 - -1.1
694,675 - -1.9
694,700 - +0.6
694,700 - +3.2
694,700 - -0.8
694,700 - -1.3
694,720 - -1.6
694,848 + -0.1
694,986 + Rv0595c 0.37 +1.6
694,986 + Rv0595c 0.37 +0.3
695,022 + Rv0595c 0.47 -0.4
695,050 + Rv0595c 0.54 +0.1
695,051 - Rv0595c 0.54 -0.8
695,223 + -0.0
695,223 + +1.0
695,556 - +0.3
695,789 + -0.4
695,789 + -0.5
695,794 + Rv0597c 0.10 +0.7
695,794 + Rv0597c 0.10 -1.7
695,794 + Rv0597c 0.10 -0.6
695,984 - Rv0597c 0.26 -0.1

Or see this region's nucleotide sequence