Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3810

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
4,273,476	-				+0.2
4,273,476	-				+0.3
4,273,476	-				+0.3
4,273,957	-		Rv3810	0.25	+0.5
4,273,957	-		Rv3810	0.25	-3.0
4,274,452	-		Rv3810	0.83	+0.2
4,274,591	+				-0.0
4,274,659	+				+1.5
4,274,660	-				+0.1
4,274,660	-				-0.0
4,274,667	+				-0.1
4,274,668	-				-0.2
4,274,677	+				-0.6
4,274,677	+				-2.6
4,274,677	+				-0.2
4,274,678	-				-0.1
4,274,678	-				+0.0
4,274,678	-				-0.5
4,274,678	-				-0.5
4,274,723	+				-0.6
4,274,744	+				-0.7
4,274,929	-				+1.5
4,274,990	-		Rv3811	0.12	-0.9
4,275,042	-		Rv3811	0.15	+0.0
4,275,054	-		Rv3811	0.16	-1.1
4,275,446	+		Rv3811	0.40	-0.3
4,275,447	-		Rv3811	0.40	-0.8
4,275,500	+		Rv3811	0.43	+2.5
4,275,539	+		Rv3811	0.46	-1.3
4,275,539	+		Rv3811	0.46	+1.5
4,275,539	+		Rv3811	0.46	-0.9
4,275,540	-		Rv3811	0.46	-0.9
4,275,540	-		Rv3811	0.46	-1.1
4,275,540	-		Rv3811	0.46	+1.3
4,275,540	-		Rv3811	0.46	+0.9
4,275,540	-		Rv3811	0.46	-0.4
4,275,546	-		Rv3811	0.46	-1.0
4,275,581	+		Rv3811	0.48	+0.7