Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3777

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
4,221,700	+		Rv3776	0.39	+2.4
4,221,808	+		Rv3776	0.46	-0.6
4,221,808	+		Rv3776	0.46	+0.5
4,221,808	+		Rv3776	0.46	-0.1
4,221,808	+		Rv3776	0.46	-0.3
4,221,823	+		Rv3776	0.47	-0.5
4,221,906	+		Rv3776	0.52	-0.3
4,221,907	-		Rv3776	0.52	-0.8
4,222,221	-		Rv3776	0.73	-1.3
4,222,361	+		Rv3776	0.82	-1.5
4,222,362	-		Rv3776	0.82	+0.5
4,222,362	-		Rv3776	0.82	+1.7
4,222,362	-		Rv3776	0.82	-0.3
4,222,392	+		Rv3776	0.84	+0.1
4,222,393	-		Rv3776	0.84	-0.1
4,222,393	-		Rv3776	0.84	-0.5
4,222,396	+		Rv3776	0.84	-0.2
4,222,397	-		Rv3776	0.84	+0.1
4,222,397	-		Rv3776	0.84	+1.2
4,222,423	-		Rv3776	0.86	-1.5
4,222,519	+				-0.6
4,222,576	+				-2.2
4,222,740	+				-0.3
4,222,741	-				-2.3
4,222,827	+		Rv3777	0.13	-1.4
4,222,828	-		Rv3777	0.14	+0.5
4,222,844	+		Rv3777	0.15	-0.7
4,222,844	+		Rv3777	0.15	-0.5
4,222,863	+		Rv3777	0.17	-1.5
4,222,983	-		Rv3777	0.29	-1.6
4,223,311	+		Rv3777	0.63	-0.6
4,223,352	-		Rv3777	0.67	-0.7
4,223,397	+		Rv3777	0.71	-0.1
4,223,397	+		Rv3777	0.71	-0.5
4,223,476	+		Rv3777	0.79	-0.7
4,223,676	+				-0.1
4,223,677	-				-1.9
4,223,678	+				-0.4
4,223,679	-				-0.2
4,223,679	-				-1.7
4,223,679	-				+0.7