Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3529c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3528c and Rv3529c are separated by 691 nucleotidesRv3529c and Rv3530c overlap by 1 nucleotidesRv3530c and Rv3531c overlap by 4 nucleotides Rv3528c: Rv3528c - Unknown protein, at 3,964,479 to 3,965,192 Rv3528c Rv3529c: Rv3529c - Conserved hypothetical protein, at 3,965,884 to 3,967,038 Rv3529c Rv3530c: Rv3530c - Possible oxidoreductase, at 3,967,038 to 3,967,820 Rv3530c Rv3531c: Rv3531c - Hypothetical protein, at 3,967,817 to 3,968,944 Rv3531c Position (kb) 3965 3966 3967 3968Strain fitness (log2 ratio) -2 -1 0 1at 3964.946 kb on + strand, within Rv3528cat 3965.014 kb on - strand, within Rv3528cat 3965.204 kb on + strandat 3965.237 kb on - strandat 3965.443 kb on + strandat 3965.559 kb on - strandat 3965.838 kb on + strandat 3966.048 kb on + strand, within Rv3529cat 3966.049 kb on - strand, within Rv3529cat 3966.331 kb on + strand, within Rv3529cat 3966.479 kb on + strand, within Rv3529cat 3966.479 kb on + strand, within Rv3529cat 3966.479 kb on + strand, within Rv3529cat 3966.899 kb on + strand, within Rv3529cat 3967.459 kb on - strand, within Rv3530cat 3967.577 kb on - strand, within Rv3530cat 3967.609 kb on - strand, within Rv3530cat 3967.609 kb on - strand, within Rv3530cat 3967.902 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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3,964,946 + Rv3528c 0.65 -0.7
3,965,014 - Rv3528c 0.75 -1.8
3,965,204 + +0.5
3,965,237 - -0.8
3,965,443 + +1.3
3,965,559 - -1.4
3,965,838 + -0.4
3,966,048 + Rv3529c 0.14 +0.7
3,966,049 - Rv3529c 0.14 +1.0
3,966,331 + Rv3529c 0.39 -0.2
3,966,479 + Rv3529c 0.52 -0.4
3,966,479 + Rv3529c 0.52 +0.6
3,966,479 + Rv3529c 0.52 -0.2
3,966,899 + Rv3529c 0.88 +0.4
3,967,459 - Rv3530c 0.54 -1.0
3,967,577 - Rv3530c 0.69 -0.4
3,967,609 - Rv3530c 0.73 -0.3
3,967,609 - Rv3530c 0.73 -0.0
3,967,902 + -1.0

Or see this region's nucleotide sequence