Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3392c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3391 and Rv3392c are separated by 0 nucleotidesRv3392c and Rv3393 are separated by 23 nucleotides Rv3391: Rv3391 - Possible multi-functional enzyme with acyl-CoA-reductase activity AcrA1, at 3,805,621 to 3,807,573 Rv3391 Rv3392c: Rv3392c - Cyclopropane-fatty-acyl-phospholipid synthase 1 CmaA1 (cyclopropane fatty acid synthase) (CFA synthase) (cyclopropane mycolic acid synthase 1), at 3,807,574 to 3,808,437 Rv3392c Rv3393: Rv3393 - Probable nucleoside hydrolase IunH (purine nucleosidase), at 3,808,461 to 3,809,387 Rv3393 Position (kb) 3807 3808 3809Strain fitness (log2 ratio) -1 0 1 2 3at 3806.787 kb on - strand, within Rv3391at 3806.983 kb on + strand, within Rv3391at 3806.983 kb on + strand, within Rv3391at 3807.377 kb on - strand, within Rv3391at 3807.644 kb on + strandat 3807.652 kb on - strandat 3808.328 kb on + strand, within Rv3392cat 3808.341 kb on - strand, within Rv3392cat 3808.449 kb on - strandat 3808.471 kb on + strandat 3808.518 kb on + strandat 3808.717 kb on + strand, within Rv3393at 3809.134 kb on - strand, within Rv3393at 3809.167 kb on - strand, within Rv3393at 3809.175 kb on + strand, within Rv3393at 3809.176 kb on - strand, within Rv3393at 3809.177 kb on + strand, within Rv3393at 3809.178 kb on - strand, within Rv3393

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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3,806,787 - Rv3391 0.60 +2.4
3,806,983 + Rv3391 0.70 -0.1
3,806,983 + Rv3391 0.70 +3.2
3,807,377 - Rv3391 0.90 +1.6
3,807,644 + -0.1
3,807,652 - -1.0
3,808,328 + Rv3392c 0.87 +0.6
3,808,341 - Rv3392c 0.89 +0.7
3,808,449 - +0.6
3,808,471 + -0.3
3,808,518 + -0.3
3,808,717 + Rv3393 0.28 -1.2
3,809,134 - Rv3393 0.73 +0.4
3,809,167 - Rv3393 0.76 +0.6
3,809,175 + Rv3393 0.77 +0.3
3,809,176 - Rv3393 0.77 -0.4
3,809,177 + Rv3393 0.77 -0.2
3,809,178 - Rv3393 0.77 -0.1

Or see this region's nucleotide sequence