Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3355c and Rv3356c overlap by 4 nucleotides Rv3356c and Rv3357 are separated by 123 nucleotides Rv3357 and Rv3358 overlap by 4 nucleotides Rv3358 and Rv3359 are separated by 41 nucleotides
Rv3355c: Rv3355c - Probable integral membrane protein, at 3,769,514 to 3,769,807
Rv3355c
Rv3356c: Rv3356c - Probable bifunctional protein FolD: methylenetetrahydrofolate dehydrogenase + methenyltetrahydrofolate cyclohydrolase, at 3,769,804 to 3,770,649
Rv3356c
Rv3357: Rv3357 - Antitoxin RelJ, at 3,770,773 to 3,771,048
Rv3357
Rv3358: Rv3358 - Toxin RelK, at 3,771,045 to 3,771,302
Rv3358
Rv3359: Rv3359 - Possible oxidoreductase, at 3,771,344 to 3,772,534
Rv3359
Position (kb)
3770
3771
3772 Strain fitness (log2 ratio)
-2
-1
0
1
2
3 at 3770.751 kb on - strand at 3770.899 kb on + strand, within Rv3357 at 3770.923 kb on + strand, within Rv3357 at 3770.923 kb on + strand, within Rv3357 at 3770.924 kb on - strand, within Rv3357 at 3770.979 kb on + strand, within Rv3357 at 3771.011 kb on + strand, within Rv3357 at 3771.011 kb on + strand, within Rv3357 at 3771.011 kb on + strand, within Rv3357 at 3771.012 kb on - strand, within Rv3357 at 3771.211 kb on - strand, within Rv3358 at 3771.249 kb on + strand, within Rv3358 at 3771.250 kb on - strand, within Rv3358 at 3771.297 kb on + strand at 3771.319 kb on - strand at 3771.319 kb on - strand at 3771.333 kb on - strand at 3771.533 kb on + strand, within Rv3359 at 3771.628 kb on - strand, within Rv3359 at 3771.862 kb on + strand, within Rv3359 at 3771.863 kb on - strand, within Rv3359 at 3771.863 kb on - strand, within Rv3359 at 3771.863 kb on - strand, within Rv3359 at 3771.866 kb on + strand, within Rv3359 at 3771.866 kb on + strand, within Rv3359 at 3771.866 kb on + strand, within Rv3359 at 3771.866 kb on + strand, within Rv3359 at 3771.866 kb on + strand, within Rv3359 at 3771.866 kb on + strand, within Rv3359 at 3771.867 kb on - strand, within Rv3359 at 3771.867 kb on - strand, within Rv3359 at 3771.948 kb on + strand, within Rv3359
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 3,770,751 - -0.3 3,770,899 + Rv3357 0.46 -1.9 3,770,923 + Rv3357 0.54 -0.6 3,770,923 + Rv3357 0.54 -0.1 3,770,924 - Rv3357 0.55 -0.9 3,770,979 + Rv3357 0.75 -2.7 3,771,011 + Rv3357 0.86 -2.6 3,771,011 + Rv3357 0.86 -1.8 3,771,011 + Rv3357 0.86 -1.8 3,771,012 - Rv3357 0.87 +3.2 3,771,211 - Rv3358 0.64 +0.6 3,771,249 + Rv3358 0.79 -0.1 3,771,250 - Rv3358 0.79 +0.7 3,771,297 + -0.9 3,771,319 - +0.8 3,771,319 - -0.9 3,771,333 - -0.2 3,771,533 + Rv3359 0.16 -0.8 3,771,628 - Rv3359 0.24 -0.5 3,771,862 + Rv3359 0.43 -0.5 3,771,863 - Rv3359 0.44 -0.8 3,771,863 - Rv3359 0.44 -0.4 3,771,863 - Rv3359 0.44 -0.7 3,771,866 + Rv3359 0.44 +0.2 3,771,866 + Rv3359 0.44 -1.9 3,771,866 + Rv3359 0.44 -1.8 3,771,866 + Rv3359 0.44 -2.2 3,771,866 + Rv3359 0.44 +0.0 3,771,866 + Rv3359 0.44 +0.6 3,771,867 - Rv3359 0.44 -1.2 3,771,867 - Rv3359 0.44 -0.9 3,771,948 + Rv3359 0.51 -0.7
Or see this region's nucleotide sequence