Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv3180c and Rv3181c are separated by 2 nucleotides Rv3181c and Rv3182 are separated by 230 nucleotides Rv3182 and Rv3183 overlap by 4 nucleotides Rv3183 and Rv3184 are separated by 236 nucleotides Rv3184 and Rv3185 overlap by 52 nucleotides
Rv3180c: Rv3180c - Hypothetical alanine rich protein, at 3,549,254 to 3,549,688
Rv3180c
Rv3181c: Rv3181c - Conserved protein, at 3,549,691 to 3,550,143
Rv3181c
Rv3182: Rv3182 - Conserved hypothetical protein, at 3,550,374 to 3,550,718
Rv3182
Rv3183: Rv3183 - Possible transcriptional regulatory protein, at 3,550,715 to 3,551,044
Rv3183
Rv3184: Rv3184 - Probable transposase for insertion sequence element IS6110 (fragment), at 3,551,281 to 3,551,607
Rv3184
Rv3185: Rv3185 - Probable transposase, at 3,551,556 to 3,552,542
Rv3185
Position (kb)
3550
3551 Strain fitness (log2 ratio)
-1
0
1
2 at 3549.395 kb on + strand, within Rv3180c at 3549.518 kb on + strand, within Rv3180c at 3549.519 kb on - strand, within Rv3180c at 3549.608 kb on + strand, within Rv3180c at 3549.609 kb on - strand, within Rv3180c at 3549.675 kb on + strand at 3549.944 kb on - strand, within Rv3181c at 3550.257 kb on - strand at 3550.345 kb on - strand at 3550.468 kb on - strand, within Rv3182 at 3550.970 kb on + strand, within Rv3183 at 3551.047 kb on + strand at 3551.133 kb on - strand at 3551.133 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 3,549,395 + Rv3180c 0.32 +0.4 3,549,518 + Rv3180c 0.61 -0.5 3,549,519 - Rv3180c 0.61 +2.1 3,549,608 + Rv3180c 0.81 +0.1 3,549,609 - Rv3180c 0.82 +1.2 3,549,675 + -0.1 3,549,944 - Rv3181c 0.56 -1.4 3,550,257 - -0.9 3,550,345 - -0.5 3,550,468 - Rv3182 0.27 -0.7 3,550,970 + Rv3183 0.77 +0.1 3,551,047 + +0.2 3,551,133 - -1.5 3,551,133 - +0.1
Or see this region's nucleotide sequence