Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2936

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
3,271,370	+		Rv2935	0.81	-2.8
3,271,482	+		Rv2935	0.84	+0.1
3,271,483	-		Rv2935	0.84	+0.5
3,271,575	+		Rv2935	0.86	-0.1
3,271,576	-		Rv2935	0.86	-1.8
3,271,576	-		Rv2935	0.86	-0.2
3,271,808	+				-0.6
3,271,908	+				-0.8
3,271,908	+				-0.8
3,271,909	-				-0.7
3,271,985	+				-1.1
3,271,986	-				-0.9
3,271,986	-				-1.3
3,272,021	+				-1.2
3,272,022	-				-0.3
3,272,022	-				-0.6
3,272,146	-				-0.7
3,272,263	-				-1.9
3,272,452	+		Rv2936	0.24	-1.8
3,272,453	-		Rv2936	0.24	-1.4
3,272,605	+		Rv2936	0.39	+0.0
3,272,606	-		Rv2936	0.39	-0.9
3,272,606	-		Rv2936	0.39	-0.6
3,272,606	-		Rv2936	0.39	-1.1
3,272,634	+		Rv2936	0.42	+2.2
3,272,634	+		Rv2936	0.42	-0.8
3,272,635	-		Rv2936	0.42	-0.5
3,272,660	-		Rv2936	0.45	-1.5
3,272,660	-		Rv2936	0.45	+0.2
3,272,704	+		Rv2936	0.49	-0.4
3,272,704	+		Rv2936	0.49	-0.2
3,272,705	-		Rv2936	0.49	-1.5
3,272,747	+		Rv2936	0.54	-0.5
3,272,748	-		Rv2936	0.54	-1.0
3,272,808	+		Rv2936	0.60	-1.0
3,272,809	-		Rv2936	0.60	-1.0
3,272,864	-		Rv2936	0.65	-0.8
3,272,958	-		Rv2936	0.75	-1.4
3,273,029	+		Rv2936	0.82	+1.8
3,273,029	+		Rv2936	0.82	-1.4
3,273,052	+		Rv2936	0.84	-2.9
3,273,052	+		Rv2936	0.84	-0.3
3,273,052	+		Rv2936	0.84	-1.7
3,273,052	+		Rv2936	0.84	-0.6
3,273,052	+		Rv2936	0.84	+0.0
3,273,052	+		Rv2936	0.84	-0.2
3,273,052	+		Rv2936	0.84	-0.9
3,273,053	-		Rv2936	0.84	-1.6
3,273,053	-		Rv2936	0.84	+0.3
3,273,053	-		Rv2936	0.84	-1.0
3,273,053	-		Rv2936	0.84	-0.8
3,273,056	+		Rv2936	0.85	-2.0
3,273,056	+		Rv2936	0.85	-0.8
3,273,056	+		Rv2936	0.85	-1.3
3,273,056	+		Rv2936	0.85	-2.8
3,273,056	+		Rv2936	0.85	-0.9
3,273,057	-		Rv2936	0.85	-1.3
3,273,057	-		Rv2936	0.85	-1.5
3,273,057	-		Rv2936	0.85	-1.3
3,273,057	-		Rv2936	0.85	-0.9
3,273,103	+		Rv2936	0.89	-1.6
3,273,103	+		Rv2936	0.89	-1.9
3,273,110	+				-2.0
3,273,143	-				-1.0
3,273,222	+				-0.7
3,273,223	-				-0.6
3,273,223	-				-1.9
3,273,223	-				-1.1
3,273,351	+		Rv2937	0.17	-2.0
3,273,351	+		Rv2937	0.17	+1.0
3,273,351	+		Rv2937	0.17	-2.0
3,273,351	+		Rv2937	0.17	-1.4
3,273,352	-		Rv2937	0.17	-0.5
3,273,352	-		Rv2937	0.17	-1.4
3,273,395	+		Rv2937	0.22	-1.1
3,273,395	+		Rv2937	0.22	-1.5
3,273,395	+		Rv2937	0.22	-1.8
3,273,396	-		Rv2937	0.22	-1.9
3,273,396	-		Rv2937	0.22	-0.5
3,273,396	-		Rv2937	0.22	-1.1
3,273,396	-		Rv2937	0.22	-1.1
3,273,396	-		Rv2937	0.22	+1.8
3,273,398	-		Rv2937	0.22	-1.6
3,273,412	-		Rv2937	0.24	-0.4
3,273,462	+		Rv2937	0.29	-1.0
3,273,470	+		Rv2937	0.30	+1.4
3,273,470	+		Rv2937	0.30	-0.5
3,273,470	+		Rv2937	0.30	-1.0
3,273,471	-		Rv2937	0.30	-2.3
3,273,471	-		Rv2937	0.30	-2.1
3,273,471	-		Rv2937	0.30	-1.6
3,273,471	-		Rv2937	0.30	-1.5
3,273,471	-		Rv2937	0.30	-1.2
3,273,661	-		Rv2937	0.52	-0.0
3,273,672	-		Rv2937	0.54	-0.8
3,273,707	+		Rv2937	0.58	-0.9
3,273,955	+		Rv2937	0.86	-1.2
3,273,955	+		Rv2937	0.86	-0.1
3,273,956	-		Rv2937	0.86	-0.5
3,274,184	+		Rv2938	0.13	-1.8
3,274,185	-		Rv2938	0.14	-1.7
3,274,204	+		Rv2938	0.16	-1.3
3,274,205	-		Rv2938	0.16	-2.2
3,274,206	+		Rv2938	0.16	-1.1
3,274,206	+		Rv2938	0.16	-1.9
3,274,207	-		Rv2938	0.16	+0.9