Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2932

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
3,250,280	+		Rv2931	0.86	-0.9
3,250,280	+		Rv2931	0.86	-1.1
3,250,280	+		Rv2931	0.86	+0.8
3,250,280	+		Rv2931	0.86	-1.0
3,250,281	-		Rv2931	0.86	-1.5
3,250,312	+		Rv2931	0.86	-1.3
3,250,313	-		Rv2931	0.86	-1.2
3,250,351	-		Rv2931	0.87	-1.1
3,250,402	-		Rv2931	0.88	+0.3
3,250,402	-		Rv2931	0.88	-0.6
3,250,419	+		Rv2931	0.88	-1.1
3,250,420	-		Rv2931	0.88	+0.5
3,250,537	+				-1.9
3,250,537	+				-0.7
3,250,678	-				-3.3
3,250,678	-				+0.8
3,250,678	-				-0.9
3,250,681	+				-0.6
3,250,681	+				-1.2
3,250,681	+				+0.8
3,251,309	+				-1.0
3,251,488	-				-0.5
3,251,537	+		Rv2932	0.10	+1.8
3,251,549	+		Rv2932	0.10	-1.0
3,251,584	-		Rv2932	0.11	-1.2
3,251,584	-		Rv2932	0.11	-1.1
3,251,640	-		Rv2932	0.12	-0.2
3,251,801	-		Rv2932	0.16	-0.6
3,251,995	-		Rv2932	0.20	-0.0
3,252,078	-		Rv2932	0.22	-0.3
3,252,440	-		Rv2932	0.30	-0.1
3,252,506	-		Rv2932	0.31	-1.6
3,252,506	-		Rv2932	0.31	-1.1
3,252,753	+		Rv2932	0.36	-2.0
3,252,913	-		Rv2932	0.40	-2.8
3,252,913	-		Rv2932	0.40	-1.0
3,252,972	+		Rv2932	0.41	-1.2
3,252,973	-		Rv2932	0.41	-0.9
3,253,634	+		Rv2932	0.55	-1.3
3,253,634	+		Rv2932	0.55	-0.2
3,253,727	-		Rv2932	0.58	+0.9
3,253,843	+		Rv2932	0.60	-0.7
3,253,843	+		Rv2932	0.60	-1.6
3,254,108	+		Rv2932	0.66	-1.3
3,254,108	+		Rv2932	0.66	+0.2
3,254,109	-		Rv2932	0.66	-0.8
3,254,109	-		Rv2932	0.66	-1.8
3,254,329	-		Rv2932	0.71	-1.0
3,254,446	-		Rv2932	0.73	-0.8
3,254,751	+		Rv2932	0.80	-0.9
3,254,751	+		Rv2932	0.80	-0.5
3,254,772	-		Rv2932	0.80	-2.1
3,254,772	-		Rv2932	0.80	-1.2
3,254,961	-		Rv2932	0.84	-1.7
3,255,219	-		Rv2932	0.90	-1.9
3,255,243	+				-0.3
3,255,624	-				-1.0
3,255,672	+				-1.1
3,255,672	+				-1.9
3,255,923	-				-0.3
3,255,925	+				+0.8
3,255,925	+				-1.2
3,255,926	-				-1.0
3,256,095	-				-0.6
3,256,132	-				+0.0
3,256,171	+				-0.8
3,256,171	+				-1.1
3,256,171	+				-0.6
3,256,171	+				+1.8
3,256,172	-				-0.6
3,256,172	-				-0.4
3,256,219	+				+0.6
3,256,219	+				-0.8
3,256,267	+				-0.7
3,256,267	+				-0.7
3,256,268	-				-0.4
3,256,268	-				-0.4
3,256,374	+		Rv2933	0.10	-1.0
3,256,495	+		Rv2933	0.12	-0.4
3,256,496	-		Rv2933	0.12	-0.3