Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2769c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2768c and Rv2769c are separated by 79 nucleotidesRv2769c and Rv2770c are separated by 323 nucleotides Rv2768c: Rv2768c - PPE family protein PPE43, at 3,076,894 to 3,078,078 Rv2768c Rv2769c: Rv2769c - PE family protein PE27, at 3,078,158 to 3,078,985 Rv2769c Rv2770c: Rv2770c - PPE family protein PPE44, at 3,079,309 to 3,080,457 Rv2770c Position (kb) 3078 3079Strain fitness (log2 ratio) -2 -1 0 1 2at 3077.361 kb on + strand, within Rv2768cat 3077.446 kb on + strand, within Rv2768cat 3077.618 kb on + strand, within Rv2768cat 3077.624 kb on + strand, within Rv2768cat 3077.624 kb on + strand, within Rv2768cat 3077.624 kb on + strand, within Rv2768cat 3077.624 kb on + strand, within Rv2768cat 3077.625 kb on - strand, within Rv2768cat 3077.625 kb on - strand, within Rv2768cat 3077.625 kb on - strand, within Rv2768cat 3077.625 kb on - strand, within Rv2768cat 3077.660 kb on + strand, within Rv2768cat 3077.661 kb on - strand, within Rv2768cat 3077.847 kb on - strand, within Rv2768cat 3077.847 kb on - strand, within Rv2768cat 3077.847 kb on - strand, within Rv2768cat 3077.847 kb on - strand, within Rv2768cat 3077.865 kb on - strand, within Rv2768cat 3077.865 kb on - strand, within Rv2768cat 3077.919 kb on + strand, within Rv2768cat 3077.959 kb on - strand, within Rv2768cat 3078.033 kb on - strandat 3078.061 kb on + strandat 3078.093 kb on + strandat 3078.093 kb on + strandat 3078.093 kb on + strandat 3078.093 kb on + strandat 3078.094 kb on - strandat 3078.094 kb on - strandat 3078.103 kb on + strandat 3078.103 kb on + strandat 3078.104 kb on - strandat 3078.159 kb on + strandat 3078.160 kb on - strandat 3078.161 kb on + strandat 3078.199 kb on - strandat 3078.397 kb on + strand, within Rv2769cat 3078.607 kb on + strand, within Rv2769cat 3078.607 kb on + strand, within Rv2769cat 3078.608 kb on - strand, within Rv2769cat 3078.608 kb on - strand, within Rv2769cat 3078.608 kb on - strand, within Rv2769cat 3078.723 kb on + strand, within Rv2769cat 3078.723 kb on + strand, within Rv2769cat 3078.724 kb on - strand, within Rv2769cat 3078.724 kb on - strand, within Rv2769cat 3078.724 kb on - strand, within Rv2769cat 3078.724 kb on - strand, within Rv2769cat 3078.765 kb on + strand, within Rv2769cat 3078.765 kb on + strand, within Rv2769cat 3078.766 kb on - strand, within Rv2769cat 3078.766 kb on - strand, within Rv2769cat 3078.766 kb on - strand, within Rv2769cat 3078.766 kb on - strand, within Rv2769cat 3078.833 kb on + strand, within Rv2769cat 3078.833 kb on + strand, within Rv2769cat 3078.842 kb on + strand, within Rv2769cat 3078.842 kb on + strand, within Rv2769cat 3078.842 kb on + strand, within Rv2769cat 3078.842 kb on + strand, within Rv2769cat 3078.843 kb on - strand, within Rv2769cat 3078.843 kb on - strand, within Rv2769cat 3078.843 kb on - strand, within Rv2769cat 3079.000 kb on - strandat 3079.000 kb on - strandat 3079.000 kb on - strandat 3079.000 kb on - strandat 3079.000 kb on - strandat 3079.000 kb on - strandat 3079.005 kb on + strandat 3079.005 kb on + strandat 3079.006 kb on - strandat 3079.006 kb on - strandat 3079.077 kb on + strandat 3079.077 kb on + strandat 3079.078 kb on - strandat 3079.081 kb on + strandat 3079.081 kb on + strandat 3079.082 kb on - strandat 3079.142 kb on - strandat 3079.148 kb on + strandat 3079.149 kb on - strandat 3079.149 kb on - strandat 3079.152 kb on + strandat 3079.153 kb on - strandat 3079.172 kb on + strandat 3079.173 kb on - strandat 3079.332 kb on + strandat 3079.332 kb on + strandat 3079.332 kb on + strandat 3079.333 kb on - strandat 3079.333 kb on - strandat 3079.653 kb on + strand, within Rv2770cat 3079.653 kb on + strand, within Rv2770cat 3079.653 kb on + strand, within Rv2770cat 3079.654 kb on - strand, within Rv2770cat 3079.654 kb on - strand, within Rv2770cat 3079.654 kb on - strand, within Rv2770cat 3079.674 kb on + strand, within Rv2770cat 3079.675 kb on - strand, within Rv2770cat 3079.675 kb on - strand, within Rv2770cat 3079.675 kb on - strand, within Rv2770cat 3079.736 kb on - strand, within Rv2770c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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3,077,361 + Rv2768c 0.39 +1.8
3,077,446 + Rv2768c 0.47 -0.4
3,077,618 + Rv2768c 0.61 +0.6
3,077,624 + Rv2768c 0.62 -0.4
3,077,624 + Rv2768c 0.62 -1.0
3,077,624 + Rv2768c 0.62 -0.6
3,077,624 + Rv2768c 0.62 -0.3
3,077,625 - Rv2768c 0.62 -0.4
3,077,625 - Rv2768c 0.62 +0.2
3,077,625 - Rv2768c 0.62 -0.0
3,077,625 - Rv2768c 0.62 -0.2
3,077,660 + Rv2768c 0.65 -0.7
3,077,661 - Rv2768c 0.65 +0.0
3,077,847 - Rv2768c 0.80 -0.5
3,077,847 - Rv2768c 0.80 -0.6
3,077,847 - Rv2768c 0.80 -0.2
3,077,847 - Rv2768c 0.80 +1.8
3,077,865 - Rv2768c 0.82 +0.8
3,077,865 - Rv2768c 0.82 +0.2
3,077,919 + Rv2768c 0.86 +2.2
3,077,959 - Rv2768c 0.90 -0.2
3,078,033 - -0.1
3,078,061 + -0.8
3,078,093 + -0.6
3,078,093 + +1.0
3,078,093 + +0.6
3,078,093 + -1.6
3,078,094 - +0.6
3,078,094 - -0.9
3,078,103 + -0.2
3,078,103 + -0.5
3,078,104 - +0.2
3,078,159 + +0.4
3,078,160 - -0.8
3,078,161 + -0.0
3,078,199 - -0.4
3,078,397 + Rv2769c 0.29 +0.0
3,078,607 + Rv2769c 0.54 -2.1
3,078,607 + Rv2769c 0.54 +0.4
3,078,608 - Rv2769c 0.54 +2.4
3,078,608 - Rv2769c 0.54 +0.1
3,078,608 - Rv2769c 0.54 -0.3
3,078,723 + Rv2769c 0.68 -0.3
3,078,723 + Rv2769c 0.68 -0.4
3,078,724 - Rv2769c 0.68 -1.9
3,078,724 - Rv2769c 0.68 +0.1
3,078,724 - Rv2769c 0.68 +1.8
3,078,724 - Rv2769c 0.68 -0.8
3,078,765 + Rv2769c 0.73 +1.3
3,078,765 + Rv2769c 0.73 +1.4
3,078,766 - Rv2769c 0.73 -0.8
3,078,766 - Rv2769c 0.73 +0.1
3,078,766 - Rv2769c 0.73 -1.6
3,078,766 - Rv2769c 0.73 -0.2
3,078,833 + Rv2769c 0.82 -0.7
3,078,833 + Rv2769c 0.82 +1.2
3,078,842 + Rv2769c 0.83 +0.3
3,078,842 + Rv2769c 0.83 -0.2
3,078,842 + Rv2769c 0.83 -0.3
3,078,842 + Rv2769c 0.83 +2.2
3,078,843 - Rv2769c 0.83 -0.5
3,078,843 - Rv2769c 0.83 -0.0
3,078,843 - Rv2769c 0.83 -0.2
3,079,000 - -0.6
3,079,000 - -0.0
3,079,000 - -0.8
3,079,000 - -0.5
3,079,000 - +0.2
3,079,000 - -1.1
3,079,005 + -0.2
3,079,005 + -0.1
3,079,006 - -0.0
3,079,006 - -0.0
3,079,077 + -0.9
3,079,077 + +0.8
3,079,078 - +0.7
3,079,081 + -0.3
3,079,081 + +0.5
3,079,082 - +2.0
3,079,142 - -1.7
3,079,148 + +0.4
3,079,149 - -0.3
3,079,149 - -0.2
3,079,152 + -0.2
3,079,153 - +0.8
3,079,172 + -0.4
3,079,173 - -0.9
3,079,332 + +1.0
3,079,332 + -1.4
3,079,332 + +0.8
3,079,333 - +0.3
3,079,333 - +1.8
3,079,653 + Rv2770c 0.30 -0.5
3,079,653 + Rv2770c 0.30 -1.1
3,079,653 + Rv2770c 0.30 +0.2
3,079,654 - Rv2770c 0.30 -0.1
3,079,654 - Rv2770c 0.30 -0.4
3,079,654 - Rv2770c 0.30 -0.2
3,079,674 + Rv2770c 0.32 +1.4
3,079,675 - Rv2770c 0.32 -0.8
3,079,675 - Rv2770c 0.32 +0.3
3,079,675 - Rv2770c 0.32 +0.5
3,079,736 - Rv2770c 0.37 -0.7

Or see this region's nucleotide sequence