Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2612c and Rv2613c overlap by 4 nucleotides Rv2613c and Rv2614c overlap by 8 nucleotides Rv2614c and Rv2614A are separated by 108 nucleotides Rv2614A and Rv2615c overlap by 4 nucleotides
Rv2612c: Rv2612c - PI synthase PgsA1 (phosphatidylinositol synthase) (CDP-diacylglycerol--inositol-3-phosphatidyltransferase), at 2,939,959 to 2,940,612
Rv2612c
Rv2613c: Rv2613c - Conserved protein, at 2,940,609 to 2,941,196
Rv2613c
Rv2614c: Rv2614c - Probable threonyl-tRNA synthetase ThrS (threonine-tRNA synthetase)(ThrRS) (threonine-tRNA ligase), at 2,941,189 to 2,943,267
Rv2614c
Rv2614A: Rv2614A - Conserved hypothetical protein, at 2,943,376 to 2,943,603
Rv2614A
Rv2615c: Rv2615c - PE-PGRS family protein PE_PGRS45, at 2,943,600 to 2,944,985
Rv2615c
Position (kb)
2941
2942
2943
2944 Strain fitness (log2 ratio)
-2
-1
0
1 at 2940.778 kb on - strand, within Rv2613c at 2940.778 kb on - strand, within Rv2613c at 2940.938 kb on - strand, within Rv2613c at 2941.085 kb on - strand, within Rv2613c at 2941.085 kb on - strand, within Rv2613c at 2941.225 kb on - strand at 2943.340 kb on + strand at 2943.341 kb on - strand at 2943.923 kb on + strand, within Rv2615c at 2943.979 kb on + strand, within Rv2615c at 2943.980 kb on - strand, within Rv2615c at 2943.980 kb on - strand, within Rv2615c at 2943.980 kb on - strand, within Rv2615c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 2,940,778 - Rv2613c 0.29 +0.2 2,940,778 - Rv2613c 0.29 +0.2 2,940,938 - Rv2613c 0.56 +0.4 2,941,085 - Rv2613c 0.81 +0.6 2,941,085 - Rv2613c 0.81 +0.5 2,941,225 - +0.9 2,943,340 + -1.8 2,943,341 - -0.2 2,943,923 + Rv2615c 0.23 -1.3 2,943,979 + Rv2615c 0.27 -0.6 2,943,980 - Rv2615c 0.27 -0.2 2,943,980 - Rv2615c 0.27 -0.4 2,943,980 - Rv2615c 0.27 -0.8
Or see this region's nucleotide sequence