Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2581c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2580c and Rv2581c overlap by 4 nucleotidesRv2581c and Rv2582 are separated by 50 nucleotides Rv2580c: Rv2580c - Probable histidyl-tRNA synthetase HisS (histidine--tRNA ligase) (HISRS) (histidine--translase), at 2,904,821 to 2,906,092 Rv2580c Rv2581c: Rv2581c - Possible glyoxalase II (hydroxyacylglutathione hydrolase) (GLX II), at 2,906,089 to 2,906,763 Rv2581c Rv2582: Rv2582 - Probable peptidyl-prolyl cis-trans isomerase B PpiB (cyclophilin) (PPIase) (rotamase) (peptidylprolyl isomerase), at 2,906,814 to 2,907,740 Rv2582 Position (kb) 2906 2907Strain fitness (log2 ratio) -1 0 1at 2906.490 kb on - strand, within Rv2581cat 2906.532 kb on - strand, within Rv2581cat 2907.738 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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2,906,490 - Rv2581c 0.59 -1.6
2,906,532 - Rv2581c 0.66 +0.8
2,907,738 + +0.0

Or see this region's nucleotide sequence