Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2310

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
2,582,530	+				-1.5
2,582,531	-				-1.3
2,582,531	-				-0.7
2,582,562	+				-0.2
2,582,562	+				+0.8
2,582,563	-				-1.1
2,582,650	+				-1.3
2,582,676	+				+1.6
2,582,676	+				-0.7
2,582,761	+				+1.4
2,582,761	+				+2.5
2,582,761	+				+0.4
2,582,762	-				-0.2
2,582,762	-				-2.7
2,582,856	-				-0.8
2,582,856	-				-0.4
2,582,856	-				-0.6
2,582,903	+				-0.5
2,582,993	+				-1.4
2,582,994	-				-0.4
2,583,003	+				-0.7
2,583,004	-				-1.2
2,583,199	-		Rv2309A	0.53	+0.5
2,583,226	-		Rv2309A	0.63	-0.5
2,583,227	+		Rv2309A	0.63	-0.5
2,583,228	-		Rv2309A	0.64	-0.6
2,583,276	+		Rv2309A	0.80	+1.4
2,583,276	+		Rv2309A	0.80	+0.0
2,583,277	-		Rv2309A	0.81	-1.3
2,583,277	-		Rv2309A	0.81	+0.5
2,583,277	-		Rv2309A	0.81	-0.7
2,583,299	+		Rv2309A	0.88	+0.5
2,583,364	+				+1.4
2,583,427	+				+0.8
2,583,651	+		Rv2310	0.63	-1.9
2,583,651	+		Rv2310	0.63	-0.5
2,583,651	+		Rv2310	0.63	-1.3
2,583,652	-		Rv2310	0.63	-0.5
2,583,652	-		Rv2310	0.63	-0.4
2,583,755	+				+4.6
2,583,866	+				+1.4
2,583,867	-				-0.5
2,583,867	-				-2.7
2,583,919	-				-0.5
2,584,115	+		Rv2311	0.44	-0.8
2,584,115	+		Rv2311	0.44	+0.7
2,584,116	-		Rv2311	0.44	-0.0
2,584,116	-		Rv2311	0.44	-0.8
2,584,202	+		Rv2311	0.61	+0.2
2,584,202	+		Rv2311	0.61	-0.0
2,584,203	-		Rv2311	0.61	+0.7
2,584,203	-		Rv2311	0.61	+0.2
2,584,203	-		Rv2311	0.61	+0.2
2,584,203	-		Rv2311	0.61	-0.7
2,584,241	+		Rv2311	0.68	-0.4
2,584,241	+		Rv2311	0.68	-0.4
2,584,241	+		Rv2311	0.68	+1.8
2,584,241	+		Rv2311	0.68	-0.2
2,584,242	-		Rv2311	0.68	-1.4
2,584,242	-		Rv2311	0.68	+1.0
2,584,245	+		Rv2311	0.69	+0.2
2,584,245	+		Rv2311	0.69	-0.2
2,584,439	+				-0.1
2,584,440	-				-0.9
2,584,471	-				-0.5
2,584,471	-				+0.5
2,584,478	+				-0.0
2,584,479	-				-0.6
2,584,479	-				+0.0
2,584,479	-				-0.3
2,584,479	-				-0.1
2,584,648	-		Rv2312	0.60	+1.8
2,584,648	-		Rv2312	0.60	-0.6
2,584,709	+		Rv2312	0.83	+0.2
2,584,709	+		Rv2312	0.83	+0.3
2,584,710	-		Rv2312	0.83	-0.4
2,584,710	-		Rv2312	0.83	-0.3
2,584,710	-		Rv2312	0.83	+0.4
2,584,762	+				-0.2