Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2292c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2290 and Rv2291 are separated by 59 nucleotidesRv2291 and Rv2292c are separated by 0 nucleotidesRv2292c and Rv2293c are separated by 38 nucleotides Rv2290: Rv2290 - Probable conserved lipoprotein LppO, at 2,562,599 to 2,563,114 Rv2290 Rv2291: Rv2291 - Probable thiosulfate sulfurtransferase SseB, at 2,563,174 to 2,564,028 Rv2291 Rv2292c: Rv2292c - Hypothetical protein, at 2,564,029 to 2,564,253 Rv2292c Rv2293c: Rv2293c - Conserved hypothetical protein, at 2,564,292 to 2,565,032 Rv2293c Position (kb) 2564 2565Strain fitness (log2 ratio) -2 -1 0 1 2 3 4at 2563.112 kb on + strandat 2563.297 kb on + strand, within Rv2291at 2563.301 kb on + strand, within Rv2291at 2563.302 kb on - strand, within Rv2291at 2563.326 kb on - strand, within Rv2291at 2563.326 kb on - strand, within Rv2291at 2563.359 kb on + strand, within Rv2291at 2563.359 kb on + strand, within Rv2291at 2563.360 kb on - strand, within Rv2291at 2563.360 kb on - strand, within Rv2291at 2563.401 kb on + strand, within Rv2291at 2564.100 kb on - strand, within Rv2292cat 2564.260 kb on + strandat 2564.322 kb on + strandat 2564.328 kb on + strandat 2564.330 kb on + strandat 2564.330 kb on + strandat 2564.331 kb on - strandat 2564.355 kb on + strandat 2564.356 kb on - strandat 2564.429 kb on + strand, within Rv2293cat 2564.753 kb on + strand, within Rv2293cat 2564.754 kb on - strand, within Rv2293cat 2564.818 kb on + strand, within Rv2293cat 2564.818 kb on + strand, within Rv2293cat 2564.819 kb on - strand, within Rv2293cat 2564.821 kb on + strand, within Rv2293cat 2565.040 kb on + strandat 2565.149 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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2,563,112 + -1.6
2,563,297 + Rv2291 0.14 +4.4
2,563,301 + Rv2291 0.15 -0.5
2,563,302 - Rv2291 0.15 +0.1
2,563,326 - Rv2291 0.18 -0.4
2,563,326 - Rv2291 0.18 -1.3
2,563,359 + Rv2291 0.22 +0.8
2,563,359 + Rv2291 0.22 -0.5
2,563,360 - Rv2291 0.22 -1.0
2,563,360 - Rv2291 0.22 +0.4
2,563,401 + Rv2291 0.27 -1.4
2,564,100 - Rv2292c 0.32 +2.1
2,564,260 + +0.2
2,564,322 + +0.1
2,564,328 + -0.3
2,564,330 + -2.1
2,564,330 + -0.3
2,564,331 - +0.5
2,564,355 + +1.0
2,564,356 - -1.2
2,564,429 + Rv2293c 0.18 -1.4
2,564,753 + Rv2293c 0.62 +0.2
2,564,754 - Rv2293c 0.62 -1.0
2,564,818 + Rv2293c 0.71 -0.1
2,564,818 + Rv2293c 0.71 -0.5
2,564,819 - Rv2293c 0.71 -1.8
2,564,821 + Rv2293c 0.71 -1.4
2,565,040 + -0.5
2,565,149 - +0.8

Or see this region's nucleotide sequence