Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1940 and Rv1941 overlap by 4 nucleotides Rv1941 and Rv1942c are separated by 209 nucleotides Rv1942c and Rv1943c overlap by 4 nucleotides Rv1943c and Rv1944c overlap by 4 nucleotides
Rv1940: Rv1940 - Probable riboflavin biosynthesis protein RibA1 (GTP cyclohydrolase II), at 2,192,606 to 2,193,667
Rv1940
Rv1941: Rv1941 - Probable short-chain type dehydrogenase/reductase, at 2,193,664 to 2,194,434
Rv1941
Rv1942c: Rv1942c - Possible toxin MazF5, at 2,194,644 to 2,194,973
Rv1942c
Rv1943c: Rv1943c - Possible antitoxin MazE5, at 2,194,970 to 2,195,347
Rv1943c
Rv1944c: Rv1944c - Conserved protein, at 2,195,344 to 2,195,934
Rv1944c
Position (kb)
2193
2194
2195 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 2192.700 kb on - strand at 2193.465 kb on - strand, within Rv1940 at 2193.465 kb on - strand, within Rv1940 at 2193.465 kb on - strand, within Rv1940 at 2193.575 kb on + strand at 2193.575 kb on + strand at 2193.575 kb on + strand at 2193.575 kb on + strand at 2193.576 kb on - strand at 2193.576 kb on - strand at 2193.576 kb on - strand at 2194.124 kb on - strand, within Rv1941 at 2194.493 kb on + strand at 2195.004 kb on - strand at 2195.055 kb on + strand, within Rv1943c at 2195.056 kb on - strand, within Rv1943c at 2195.056 kb on - strand, within Rv1943c
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 2,192,700 - +2.2 2,193,465 - Rv1940 0.81 +0.2 2,193,465 - Rv1940 0.81 -1.3 2,193,465 - Rv1940 0.81 -1.1 2,193,575 + -1.0 2,193,575 + -0.4 2,193,575 + -0.9 2,193,575 + +0.1 2,193,576 - +0.0 2,193,576 - +0.5 2,193,576 - -0.5 2,194,124 - Rv1941 0.60 -1.9 2,194,493 + -0.4 2,195,004 - -0.2 2,195,055 + Rv1943c 0.22 +2.5 2,195,056 - Rv1943c 0.23 -1.2 2,195,056 - Rv1943c 0.23 -0.4
Or see this region's nucleotide sequence