Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1891

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
2,138,979	-		Rv1889c	0.89	+0.2
2,138,979	-		Rv1889c	0.89	+1.3
2,139,046	+				-0.7
2,139,046	+				-0.6
2,139,046	+				-1.0
2,139,047	-				-0.5
2,139,328	-		Rv1890c	0.41	-0.4
2,139,581	-		Rv1890c	0.83	-2.3
2,139,638	+				-0.7
2,139,699	+				+0.3
2,139,852	+		Rv1891	0.27	-1.3
2,139,853	-		Rv1891	0.27	+0.9
2,139,853	-		Rv1891	0.27	-1.7
2,139,853	-		Rv1891	0.27	-0.1
2,139,853	-		Rv1891	0.27	-1.8
2,139,951	-		Rv1891	0.51	-0.8
2,139,978	+		Rv1891	0.58	-1.0
2,140,001	-		Rv1891	0.64	-1.3
2,140,002	+		Rv1891	0.64	+0.1
2,140,002	+		Rv1891	0.64	-1.1
2,140,003	-		Rv1891	0.64	-0.2
2,140,116	-				-0.6
2,140,227	+		Rv1892	0.20	-0.4
2,140,227	+		Rv1892	0.20	-0.3
2,140,228	-		Rv1892	0.20	-0.3
2,140,255	+		Rv1892	0.29	-0.4
2,140,255	+		Rv1892	0.29	+2.5
2,140,255	+		Rv1892	0.29	+0.3
2,140,256	-		Rv1892	0.29	-1.3
2,140,256	-		Rv1892	0.29	-0.4
2,140,256	-		Rv1892	0.29	-0.7
2,140,256	-		Rv1892	0.29	-0.4
2,140,257	+		Rv1892	0.29	-0.8
2,140,355	+		Rv1892	0.61	-1.7
2,140,475	-				-0.6
2,140,791	+				+0.1
2,140,903	+		Rv1894c	0.15	+1.5
2,140,903	+		Rv1894c	0.15	+0.7
2,140,903	+		Rv1894c	0.15	+0.0
2,140,903	+		Rv1894c	0.15	+0.1
2,140,904	-		Rv1894c	0.15	-2.0
2,140,904	-		Rv1894c	0.15	-0.1
2,140,938	+		Rv1894c	0.18	-0.3
2,140,938	+		Rv1894c	0.18	+0.2
2,140,938	+		Rv1894c	0.18	-0.1
2,140,938	+		Rv1894c	0.18	+0.7
2,140,938	+		Rv1894c	0.18	-0.5
2,140,939	-		Rv1894c	0.18	+0.3
2,140,939	-		Rv1894c	0.18	-0.4
2,140,952	-		Rv1894c	0.19	-0.6
2,141,073	+		Rv1894c	0.30	+0.3
2,141,073	+		Rv1894c	0.30	+1.1
2,141,074	-		Rv1894c	0.30	-0.3