Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv1713 and Rv1714 are separated by 173 nucleotides Rv1714 and Rv1715 overlap by 7 nucleotides Rv1715 and Rv1716 are separated by 2 nucleotides Rv1716 and Rv1717 overlap by 1 nucleotides
Rv1713: Rv1713 - Probable GTP-binding protein EngA, at 1,940,288 to 1,941,679
Rv1713
Rv1714: Rv1714 - Probable oxidoreductase, at 1,941,853 to 1,942,665
Rv1714
Rv1715: Rv1715 - Probable 3-hydroxybutyryl-CoA dehydrogenase FadB3 (beta-hydroxybutyryl-CoA dehydrogenase) (BHBD), at 1,942,659 to 1,943,573
Rv1715
Rv1716: Rv1716 - Conserved hypothetical protein, at 1,943,576 to 1,944,406
Rv1716
Rv1717: Rv1717 - Conserved hypothetical protein, at 1,944,406 to 1,944,756
Rv1717
Position (kb)
1942
1943
1944 Strain fitness (log2 ratio)
-3
-2
-1
0
1 at 1942.191 kb on + strand, within Rv1714 at 1942.192 kb on - strand, within Rv1714 at 1942.636 kb on + strand at 1942.859 kb on - strand, within Rv1715 at 1943.340 kb on + strand, within Rv1715 at 1943.340 kb on + strand, within Rv1715 at 1943.625 kb on - strand at 1943.670 kb on - strand, within Rv1716 at 1943.963 kb on + strand, within Rv1716 at 1943.964 kb on - strand, within Rv1716 at 1943.964 kb on - strand, within Rv1716 at 1943.981 kb on + strand, within Rv1716 at 1943.985 kb on - strand, within Rv1716 at 1943.990 kb on + strand, within Rv1716 at 1944.239 kb on + strand, within Rv1716 at 1944.239 kb on + strand, within Rv1716 at 1944.240 kb on - strand, within Rv1716 at 1944.440 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 1,942,191 + Rv1714 0.42 -0.5 1,942,192 - Rv1714 0.42 -0.1 1,942,636 + +0.1 1,942,859 - Rv1715 0.22 -2.9 1,943,340 + Rv1715 0.74 -2.0 1,943,340 + Rv1715 0.74 -0.6 1,943,625 - -1.3 1,943,670 - Rv1716 0.11 +0.4 1,943,963 + Rv1716 0.47 -0.3 1,943,964 - Rv1716 0.47 +1.1 1,943,964 - Rv1716 0.47 +0.7 1,943,981 + Rv1716 0.49 +0.5 1,943,985 - Rv1716 0.49 +0.6 1,943,990 + Rv1716 0.50 -0.6 1,944,239 + Rv1716 0.80 +0.2 1,944,239 + Rv1716 0.80 -0.4 1,944,240 - Rv1716 0.80 -0.4 1,944,440 - -0.6
Or see this region's nucleotide sequence