Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1677

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1675c and Rv1676 are separated by 71 nucleotidesRv1676 and Rv1677 overlap by 4 nucleotidesRv1677 and Rv1678 are separated by 100 nucleotides Rv1675c: Rv1675c - Probable transcriptional regulatory protein Cmr, at 1,900,241 to 1,900,975 Rv1675c Rv1676: Rv1676 - Unknown protein, at 1,901,047 to 1,901,751 Rv1676 Rv1677: Rv1677 - Probable conserved lipoprotein DsbF, at 1,901,748 to 1,902,296 Rv1677 Rv1678: Rv1678 - Probable integral membrane protein, at 1,902,397 to 1,903,299 Rv1678 Position (kb) 1901 1902 1903Strain fitness (log2 ratio) -1 0 1at 1901.164 kb on + strand, within Rv1676at 1901.165 kb on - strand, within Rv1676at 1901.170 kb on - strand, within Rv1676at 1901.181 kb on + strand, within Rv1676at 1901.467 kb on + strand, within Rv1676at 1901.668 kb on + strand, within Rv1676at 1901.778 kb on - strandat 1901.783 kb on - strandat 1902.088 kb on + strand, within Rv1677at 1902.117 kb on + strand, within Rv1677at 1902.512 kb on - strand, within Rv1678at 1902.568 kb on + strand, within Rv1678at 1902.569 kb on - strand, within Rv1678at 1902.569 kb on - strand, within Rv1678at 1903.020 kb on - strand, within Rv1678

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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1,901,164 + Rv1676 0.17 -0.7
1,901,165 - Rv1676 0.17 -1.0
1,901,170 - Rv1676 0.17 -1.1
1,901,181 + Rv1676 0.19 -1.7
1,901,467 + Rv1676 0.60 -0.1
1,901,668 + Rv1676 0.88 -0.8
1,901,778 - -0.6
1,901,783 - +1.7
1,902,088 + Rv1677 0.62 -1.7
1,902,117 + Rv1677 0.67 -0.6
1,902,512 - Rv1678 0.13 +1.2
1,902,568 + Rv1678 0.19 +0.3
1,902,569 - Rv1678 0.19 +0.4
1,902,569 - Rv1678 0.19 +0.0
1,903,020 - Rv1678 0.69 -1.2

Or see this region's nucleotide sequence