Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1091

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Moxifloxacin 0.121 ug/mL
1,215,659	+		Rv1090	0.13	+1.1
1,215,659	+		Rv1090	0.13	+0.7
1,215,660	-		Rv1090	0.13	+1.0
1,215,665	+		Rv1090	0.14	+1.6
1,215,665	+		Rv1090	0.14	+1.0
1,215,666	-		Rv1090	0.15	+2.1
1,215,666	-		Rv1090	0.15	+0.6
1,215,681	+		Rv1090	0.18	+0.9
1,215,682	-		Rv1090	0.18	+1.4
1,215,695	+		Rv1090	0.21	+1.0
1,215,695	+		Rv1090	0.21	+1.7
1,215,696	-		Rv1090	0.21	+2.7
1,215,696	-		Rv1090	0.21	+0.7
1,215,875	+		Rv1090	0.61	-0.4
1,215,875	+		Rv1090	0.61	+0.7
1,215,876	-		Rv1090	0.61	+0.7
1,215,876	-		Rv1090	0.61	+0.7
1,215,876	-		Rv1090	0.61	+0.5
1,215,876	-		Rv1090	0.61	+1.1
1,216,052	+				+3.7
1,216,053	-				+1.5
1,216,103	+				+3.0
1,216,104	-				+1.7
1,216,346	+				+1.2
1,216,346	+				+1.8
1,216,347	-				+0.3
1,216,347	-				+0.0
1,216,414	+				+0.1
1,216,415	-				+3.4
1,216,463	+				+2.3
1,216,652	+				+0.8
1,216,652	+				+1.3
1,216,652	+				+1.3
1,216,653	-				+1.7
1,216,653	-				+1.4
1,216,727	+		Rv1091	0.10	+1.4
1,216,728	-		Rv1091	0.10	+1.4
1,216,890	-		Rv1091	0.16	+1.7
1,216,918	+		Rv1091	0.18	+1.7
1,216,918	+		Rv1091	0.18	+0.1
1,216,918	+		Rv1091	0.18	+1.4
1,216,919	-		Rv1091	0.18	+1.2
1,217,039	+		Rv1091	0.22	+0.9
1,217,300	-		Rv1091	0.32	+1.1
1,217,305	+		Rv1091	0.33	+2.0
1,217,305	+		Rv1091	0.33	+1.0
1,217,306	-		Rv1091	0.33	+1.0
1,217,542	-		Rv1091	0.42	+2.0
1,217,552	-		Rv1091	0.42	+1.5
1,218,381	+		Rv1091	0.75	+0.6
1,218,381	+		Rv1091	0.75	+1.8
1,218,381	+		Rv1091	0.75	+0.9
1,218,381	+		Rv1091	0.75	+1.0
1,218,508	+		Rv1091	0.80	+0.6
1,218,785	+				+2.3
1,218,786	-				+1.7
1,218,786	-				+1.7
1,219,161	+				-1.3
1,219,161	+				+0.7
1,219,161	+				+0.2
1,219,216	-				+0.1
1,219,249	+				-1.6
1,219,249	+				+0.1
1,219,250	-				+1.1