Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1048c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1047 and Rv1048c are separated by 367 nucleotidesRv1048c and Rv1049 are separated by 232 nucleotidesRv1049 and Rv1050 are separated by 48 nucleotides Rv1047: Rv1047 - Probable transposase, at 1,169,423 to 1,170,670 Rv1047 Rv1048c: Rv1048c - Hypothetical protein, at 1,171,038 to 1,172,153 Rv1048c Rv1049: Rv1049 - Probable transcriptional repressor protein, at 1,172,386 to 1,172,832 Rv1049 Rv1050: Rv1050 - Probable oxidoreductase, at 1,172,881 to 1,173,786 Rv1050 Position (kb) 1171 1172 1173Strain fitness (log2 ratio) -2 -1 0 1 2at 1170.779 kb on + strandat 1170.849 kb on + strandat 1170.849 kb on + strandat 1170.925 kb on - strandat 1170.925 kb on - strandat 1171.059 kb on + strandat 1171.059 kb on + strandat 1171.059 kb on + strandat 1171.060 kb on - strandat 1171.060 kb on - strandat 1171.101 kb on + strandat 1171.101 kb on + strandat 1171.102 kb on - strandat 1171.112 kb on - strandat 1171.114 kb on - strandat 1171.126 kb on - strandat 1171.126 kb on - strandat 1171.137 kb on - strandat 1171.137 kb on - strandat 1171.197 kb on + strand, within Rv1048cat 1171.198 kb on - strand, within Rv1048cat 1171.471 kb on + strand, within Rv1048cat 1171.611 kb on + strand, within Rv1048cat 1171.612 kb on - strand, within Rv1048cat 1171.663 kb on - strand, within Rv1048cat 1171.689 kb on + strand, within Rv1048cat 1171.689 kb on + strand, within Rv1048cat 1171.689 kb on + strand, within Rv1048cat 1171.896 kb on + strand, within Rv1048cat 1171.983 kb on + strand, within Rv1048cat 1172.384 kb on + strandat 1172.384 kb on + strandat 1172.422 kb on + strandat 1172.422 kb on + strandat 1172.422 kb on + strandat 1172.423 kb on - strandat 1172.423 kb on - strandat 1172.423 kb on - strandat 1172.462 kb on - strand, within Rv1049at 1172.604 kb on - strand, within Rv1049at 1172.849 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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1,170,779 + -0.3
1,170,849 + -0.9
1,170,849 + -0.7
1,170,925 - +0.2
1,170,925 - -1.8
1,171,059 + -0.5
1,171,059 + +0.4
1,171,059 + -0.3
1,171,060 - +0.5
1,171,060 - +2.2
1,171,101 + +2.3
1,171,101 + +0.2
1,171,102 - +0.7
1,171,112 - +0.5
1,171,114 - +2.7
1,171,126 - -0.2
1,171,126 - -0.6
1,171,137 - -1.5
1,171,137 - +0.1
1,171,197 + Rv1048c 0.14 +1.2
1,171,198 - Rv1048c 0.14 +1.7
1,171,471 + Rv1048c 0.39 -0.3
1,171,611 + Rv1048c 0.51 +1.1
1,171,612 - Rv1048c 0.51 +1.0
1,171,663 - Rv1048c 0.56 +1.7
1,171,689 + Rv1048c 0.58 -0.4
1,171,689 + Rv1048c 0.58 -0.9
1,171,689 + Rv1048c 0.58 +1.5
1,171,896 + Rv1048c 0.77 -0.5
1,171,983 + Rv1048c 0.85 -0.2
1,172,384 + -0.7
1,172,384 + +0.3
1,172,422 + -0.6
1,172,422 + -0.9
1,172,422 + +0.1
1,172,423 - +1.7
1,172,423 - -0.1
1,172,423 - -0.5
1,172,462 - Rv1049 0.17 -0.3
1,172,604 - Rv1049 0.49 -0.4
1,172,849 - +0.8

Or see this region's nucleotide sequence