Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0560c

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0558 and Rv0559c are separated by 13 nucleotidesRv0559c and Rv0560c are separated by 33 nucleotidesRv0560c and Rv0561c are separated by 24 nucleotides Rv0558: Rv0558 - Probable ubiquinone/menaquinone biosynthesis methyltransferase MenH (2-heptaprenyl-1,4-naphthoquinone methyltransferase), at 649,689 to 650,393 Rv0558 Rv0559c: Rv0559c - Possible conserved secreted protein, at 650,407 to 650,745 Rv0559c Rv0560c: Rv0560c - Possible benzoquinone methyltransferase (methylase), at 650,779 to 651,504 Rv0560c Rv0561c: Rv0561c - Possible oxidoreductase, at 651,529 to 652,755 Rv0561c Position (kb) 650 651 652Strain fitness (log2 ratio) -2 -1 0 1 2at 650.454 kb on - strand, within Rv0559cat 650.543 kb on + strand, within Rv0559cat 650.543 kb on + strand, within Rv0559cat 650.543 kb on + strand, within Rv0559cat 650.544 kb on - strand, within Rv0559cat 650.607 kb on - strand, within Rv0559cat 650.621 kb on + strand, within Rv0559cat 650.756 kb on - strandat 650.756 kb on - strandat 650.756 kb on - strandat 650.757 kb on + strandat 650.757 kb on + strandat 650.757 kb on + strandat 650.758 kb on - strandat 650.892 kb on - strand, within Rv0560cat 650.892 kb on - strand, within Rv0560cat 651.017 kb on + strand, within Rv0560cat 651.059 kb on + strand, within Rv0560cat 651.131 kb on + strand, within Rv0560cat 651.695 kb on - strand, within Rv0561cat 652.223 kb on + strand, within Rv0561c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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650,454 - Rv0559c 0.14 -0.7
650,543 + Rv0559c 0.40 -0.4
650,543 + Rv0559c 0.40 -0.4
650,543 + Rv0559c 0.40 -1.1
650,544 - Rv0559c 0.40 +0.4
650,607 - Rv0559c 0.59 -2.4
650,621 + Rv0559c 0.63 -1.0
650,756 - -1.6
650,756 - -0.5
650,756 - -0.1
650,757 + +0.1
650,757 + -1.4
650,757 + +2.4
650,758 - -1.3
650,892 - Rv0560c 0.16 -1.4
650,892 - Rv0560c 0.16 -2.3
651,017 + Rv0560c 0.33 -0.4
651,059 + Rv0560c 0.39 -0.6
651,131 + Rv0560c 0.48 +0.3
651,695 - Rv0561c 0.14 +2.1
652,223 + Rv0561c 0.57 +0.4

Or see this region's nucleotide sequence