Experiment: 7H9 with Moxifloxacin 0.121 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0155 and Rv0156 are separated by 0 nucleotides Rv0156 and Rv0157 overlap by 4 nucleotides Rv0157 and Rv0157A are separated by 15 nucleotides Rv0157A and Rv0158 are separated by 161 nucleotides Rv0158 and Rv0159c are separated by 3 nucleotides
Rv0155: Rv0155 - Probable NAD(P) transhydrogenase (subunit alpha) PntAa [first part; catalytic part] (pyridine nucleotide transhydrogenase subunit alpha) (nicotinamide nucleotide transhydrogenase subunit alpha), at 183,622 to 184,722
Rv0155
Rv0156: Rv0156 - Probable NAD(P) transhydrogenase (subunit alpha) PntAb [second part; integral membrane protein] (pyridine nucleotide transhydrogenase subunit alpha) (nicotinamide nucleotide transhydrogenase subunit alpha), at 184,723 to 185,055
Rv0156
Rv0157: Rv0157 - Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] (pyridine nucleotide transhydrogenase subunit beta) (nicotinamide nucleotide transhydrogenase subunit beta), at 185,052 to 186,479
Rv0157
Rv0157A: Rv0157A - Conserved protein, at 186,495 to 186,623
Rv0157A
Rv0158: Rv0158 - Probable transcriptional regulatory protein (possibly TetR-family), at 186,785 to 187,429
Rv0158
Rv0159c: Rv0159c - PE family protein PE3, at 187,433 to 188,839
Rv0159c
Position (kb) 185
186
187 Strain fitness (log2 ratio) -4
-3
-2
-1
0
1
2
3
4 at 184.054 kb on - strand, within Rv0155 at 184.054 kb on - strand, within Rv0155 at 184.216 kb on + strand, within Rv0155 at 184.217 kb on - strand, within Rv0155 at 184.217 kb on - strand, within Rv0155 at 184.607 kb on - strand, within Rv0155 at 184.607 kb on - strand, within Rv0155 at 184.720 kb on + strand at 184.721 kb on - strand at 184.721 kb on - strand at 184.726 kb on + strand at 185.082 kb on + strand at 185.083 kb on - strand at 185.109 kb on + strand at 185.110 kb on - strand at 185.487 kb on - strand, within Rv0157 at 185.487 kb on - strand, within Rv0157 at 185.487 kb on - strand, within Rv0157 at 185.487 kb on - strand, within Rv0157 at 185.995 kb on - strand, within Rv0157 at 185.995 kb on - strand, within Rv0157 at 186.106 kb on - strand, within Rv0157 at 186.143 kb on + strand, within Rv0157 at 186.144 kb on - strand, within Rv0157 at 186.144 kb on - strand, within Rv0157 at 186.178 kb on - strand, within Rv0157 at 186.416 kb on + strand at 186.416 kb on + strand at 186.416 kb on + strand at 186.417 kb on - strand at 186.417 kb on - strand at 186.417 kb on - strand at 186.477 kb on + strand at 186.478 kb on - strand at 186.478 kb on - strand at 186.508 kb on + strand, within Rv0157A at 186.509 kb on - strand, within Rv0157A at 186.781 kb on - strand at 186.814 kb on - strand at 186.853 kb on - strand, within Rv0158 at 186.929 kb on + strand, within Rv0158 at 186.930 kb on - strand, within Rv0158 at 186.930 kb on - strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.935 kb on + strand, within Rv0158 at 186.936 kb on - strand, within Rv0158 at 186.971 kb on + strand, within Rv0158 at 187.043 kb on + strand, within Rv0158 at 187.103 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.121 kb on + strand, within Rv0158 at 187.122 kb on - strand, within Rv0158 at 187.185 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.195 kb on - strand, within Rv0158 at 187.235 kb on + strand, within Rv0158 at 187.269 kb on - strand, within Rv0158 at 187.292 kb on + strand, within Rv0158 at 187.292 kb on + strand, within Rv0158
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL remove 184,054 - Rv0155 0.39 -1.0 184,054 - Rv0155 0.39 -1.3 184,216 + Rv0155 0.54 +2.7 184,217 - Rv0155 0.54 -0.0 184,217 - Rv0155 0.54 -4.1 184,607 - Rv0155 0.89 -0.6 184,607 - Rv0155 0.89 +0.5 184,720 + -0.3 184,721 - -0.4 184,721 - -0.1 184,726 + +0.1 185,082 + -0.7 185,083 - -1.0 185,109 + +0.7 185,110 - -1.1 185,487 - Rv0157 0.30 -1.3 185,487 - Rv0157 0.30 +0.3 185,487 - Rv0157 0.30 -2.3 185,487 - Rv0157 0.30 +0.4 185,995 - Rv0157 0.66 -0.5 185,995 - Rv0157 0.66 -0.1 186,106 - Rv0157 0.74 -1.4 186,143 + Rv0157 0.76 -0.9 186,144 - Rv0157 0.76 -0.8 186,144 - Rv0157 0.76 +1.4 186,178 - Rv0157 0.79 -0.5 186,416 + -1.0 186,416 + +0.7 186,416 + +0.3 186,417 - -0.1 186,417 - +0.4 186,417 - -1.6 186,477 + +0.4 186,478 - -0.9 186,478 - -0.1 186,508 + Rv0157A 0.10 -0.5 186,509 - Rv0157A 0.11 -1.0 186,781 - -0.5 186,814 - -0.2 186,853 - Rv0158 0.11 -0.1 186,929 + Rv0158 0.22 -0.1 186,930 - Rv0158 0.22 -0.2 186,930 - Rv0158 0.22 -0.7 186,935 + Rv0158 0.23 -0.4 186,935 + Rv0158 0.23 -0.4 186,935 + Rv0158 0.23 +0.1 186,935 + Rv0158 0.23 -0.3 186,936 - Rv0158 0.23 +0.1 186,971 + Rv0158 0.29 +0.7 187,043 + Rv0158 0.40 +4.0 187,103 + Rv0158 0.49 +0.1 187,121 + Rv0158 0.52 -1.4 187,121 + Rv0158 0.52 +0.1 187,121 + Rv0158 0.52 +1.0 187,122 - Rv0158 0.52 -1.0 187,185 - Rv0158 0.62 -0.6 187,195 - Rv0158 0.64 +0.1 187,195 - Rv0158 0.64 +0.3 187,195 - Rv0158 0.64 +0.4 187,235 + Rv0158 0.70 -0.3 187,269 - Rv0158 0.75 +0.9 187,292 + Rv0158 0.79 +1.4 187,292 + Rv0158 0.79 -0.3
Or see this region's nucleotide sequence