Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0079

Experiment: 7H9 with Moxifloxacin 0.121 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0078A and Rv0078B overlap by 4 nucleotidesRv0078B and Rv0079 are separated by 199 nucleotidesRv0079 and Rv0080 overlap by 4 nucleotidesRv0080 and Rv0081 are separated by 94 nucleotidesRv0081 and Rv0082 are separated by 4 nucleotides Rv0078A: Rv0078A - Hypothetical protein, at 87,208 to 87,801 Rv0078A Rv0078B: Rv0078B - Conserved protein, at 87,798 to 88,004 Rv0078B Rv0079: Rv0079 - Unknown protein, at 88,204 to 89,025 Rv0079 Rv0080: Rv0080 - Conserved hypothetical protein, at 89,022 to 89,480 Rv0080 Rv0081: Rv0081 - Probable transcriptional regulatory protein, at 89,575 to 89,919 Rv0081 Rv0082: Rv0082 - Probable oxidoreductase, at 89,924 to 90,403 Rv0082 Position (kb) 88 89 90Strain fitness (log2 ratio) -2 -1 0 1 2at 87.276 kb on + strand, within Rv0078Aat 87.289 kb on - strand, within Rv0078Aat 87.343 kb on + strand, within Rv0078Aat 87.605 kb on + strand, within Rv0078Aat 87.606 kb on - strand, within Rv0078Aat 87.632 kb on - strand, within Rv0078Aat 87.955 kb on + strand, within Rv0078Bat 87.955 kb on + strand, within Rv0078Bat 87.955 kb on + strand, within Rv0078Bat 87.955 kb on + strand, within Rv0078Bat 87.955 kb on + strand, within Rv0078Bat 88.233 kb on - strandat 88.233 kb on - strandat 88.280 kb on + strandat 88.440 kb on - strand, within Rv0079at 88.631 kb on + strand, within Rv0079at 88.681 kb on + strand, within Rv0079at 88.682 kb on - strand, within Rv0079at 88.732 kb on + strand, within Rv0079at 88.779 kb on - strand, within Rv0079at 88.779 kb on - strand, within Rv0079at 88.954 kb on + strandat 88.954 kb on + strandat 89.271 kb on + strand, within Rv0080at 89.271 kb on + strand, within Rv0080at 89.272 kb on - strand, within Rv0080at 89.370 kb on + strand, within Rv0080at 89.371 kb on - strand, within Rv0080at 89.471 kb on + strandat 89.472 kb on - strandat 89.593 kb on + strandat 89.594 kb on - strandat 89.747 kb on + strand, within Rv0081at 89.917 kb on + strandat 90.015 kb on + strand, within Rv0082

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Moxifloxacin 0.121 ug/mL
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87,276 + Rv0078A 0.11 -0.4
87,289 - Rv0078A 0.14 -1.7
87,343 + Rv0078A 0.23 +0.1
87,605 + Rv0078A 0.67 -1.0
87,606 - Rv0078A 0.67 -0.2
87,632 - Rv0078A 0.71 -0.7
87,955 + Rv0078B 0.76 -1.3
87,955 + Rv0078B 0.76 -0.4
87,955 + Rv0078B 0.76 +0.3
87,955 + Rv0078B 0.76 -0.6
87,955 + Rv0078B 0.76 +0.0
88,233 - +0.6
88,233 - +2.0
88,280 + -1.9
88,440 - Rv0079 0.29 -1.9
88,631 + Rv0079 0.52 -1.0
88,681 + Rv0079 0.58 -2.6
88,682 - Rv0079 0.58 -0.3
88,732 + Rv0079 0.64 +0.6
88,779 - Rv0079 0.70 -1.7
88,779 - Rv0079 0.70 -1.6
88,954 + -0.7
88,954 + -0.4
89,271 + Rv0080 0.54 +0.2
89,271 + Rv0080 0.54 -0.1
89,272 - Rv0080 0.54 -0.3
89,370 + Rv0080 0.76 +0.9
89,371 - Rv0080 0.76 -0.3
89,471 + -1.2
89,472 - -1.4
89,593 + -1.4
89,594 - -0.0
89,747 + Rv0081 0.50 +0.5
89,917 + -0.1
90,015 + Rv0082 0.19 +0.8

Or see this region's nucleotide sequence