Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3378c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3377c and Rv3378c are separated by 4 nucleotidesRv3378c and Rv3379c are separated by 8 nucleotides Rv3377c: Rv3377c - Halimadienyl diphosphate synthase, at 3,790,848 to 3,792,353 Rv3377c Rv3378c: Rv3378c - Diterpene synthase, at 3,792,358 to 3,793,248 Rv3378c Rv3379c: Rv3379c - Probable 1-deoxy-D-xylulose 5-phosphate synthase Dxs2 (1-deoxyxylulose-5-phosphate synthase) (DXP synthase) (DXPS), at 3,793,257 to 3,794,867 Rv3379c Position (kb) 3792 3793 3794Strain fitness (log2 ratio) -1 0 1 2 3 4at 3791.406 kb on + strand, within Rv3377cat 3791.553 kb on + strand, within Rv3377cat 3791.553 kb on + strand, within Rv3377cat 3791.554 kb on - strand, within Rv3377cat 3791.554 kb on - strand, within Rv3377cat 3792.244 kb on - strandat 3792.289 kb on + strandat 3792.289 kb on + strandat 3792.289 kb on + strandat 3792.290 kb on - strandat 3792.331 kb on - strandat 3792.443 kb on - strandat 3792.548 kb on + strand, within Rv3378cat 3792.781 kb on + strand, within Rv3378cat 3793.186 kb on + strandat 3793.208 kb on - strandat 3793.336 kb on - strandat 3793.426 kb on + strand, within Rv3379cat 3793.427 kb on - strand, within Rv3379cat 3793.466 kb on + strand, within Rv3379cat 3793.503 kb on + strand, within Rv3379cat 3793.697 kb on + strand, within Rv3379cat 3793.818 kb on + strand, within Rv3379cat 3794.049 kb on + strand, within Rv3379c

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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3,791,406 + Rv3377c 0.37 +0.2
3,791,553 + Rv3377c 0.47 -0.3
3,791,553 + Rv3377c 0.47 +0.8
3,791,554 - Rv3377c 0.47 +0.7
3,791,554 - Rv3377c 0.47 -0.4
3,792,244 - +3.8
3,792,289 + +1.1
3,792,289 + -0.2
3,792,289 + +0.8
3,792,290 - +0.1
3,792,331 - -0.5
3,792,443 - -0.1
3,792,548 + Rv3378c 0.21 +0.2
3,792,781 + Rv3378c 0.47 +0.5
3,793,186 + +0.2
3,793,208 - -1.6
3,793,336 - +1.0
3,793,426 + Rv3379c 0.10 +0.8
3,793,427 - Rv3379c 0.11 +0.5
3,793,466 + Rv3379c 0.13 -0.0
3,793,503 + Rv3379c 0.15 -1.1
3,793,697 + Rv3379c 0.27 -0.3
3,793,818 + Rv3379c 0.35 -0.1
3,794,049 + Rv3379c 0.49 +0.9

Or see this region's nucleotide sequence