Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2180c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2178c and Rv2179c are separated by 90 nucleotidesRv2179c and Rv2180c are separated by 9 nucleotidesRv2180c and Rv2181 are separated by 87 nucleotides Rv2178c: Rv2178c - 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible), at 2,440,332 to 2,441,720 Rv2178c Rv2179c: Rv2179c - Conserved hypothetical protein, at 2,441,811 to 2,442,317 Rv2179c Rv2180c: Rv2180c - Probable conserved integral membrane protein, at 2,442,327 to 2,443,214 Rv2180c Rv2181: Rv2181 - Alpha(1->2)mannosyltransferase, at 2,443,302 to 2,444,585 Rv2181 Position (kb) 2442 2443 2444Strain fitness (log2 ratio) -1 0 1 2 3at 2442.460 kb on + strand, within Rv2180cat 2442.460 kb on + strand, within Rv2180cat 2442.460 kb on + strand, within Rv2180cat 2442.460 kb on + strand, within Rv2180cat 2442.461 kb on - strand, within Rv2180cat 2442.461 kb on - strand, within Rv2180cat 2442.550 kb on + strand, within Rv2180cat 2442.551 kb on - strand, within Rv2180cat 2442.551 kb on - strand, within Rv2180cat 2442.771 kb on + strand, within Rv2180cat 2442.772 kb on - strand, within Rv2180cat 2442.851 kb on - strand, within Rv2180cat 2442.880 kb on + strand, within Rv2180cat 2442.880 kb on + strand, within Rv2180cat 2443.221 kb on - strandat 2443.239 kb on + strandat 2443.239 kb on + strandat 2443.239 kb on + strandat 2443.239 kb on + strandat 2443.239 kb on + strandat 2443.240 kb on - strandat 2443.283 kb on + strandat 2443.286 kb on + strandat 2443.287 kb on - strandat 2443.395 kb on + strandat 2443.395 kb on + strandat 2443.450 kb on - strand, within Rv2181at 2443.491 kb on + strand, within Rv2181at 2443.545 kb on + strand, within Rv2181at 2443.545 kb on + strand, within Rv2181at 2443.545 kb on + strand, within Rv2181at 2443.546 kb on - strand, within Rv2181at 2443.624 kb on + strand, within Rv2181at 2443.625 kb on - strand, within Rv2181at 2444.032 kb on - strand, within Rv2181at 2444.042 kb on + strand, within Rv2181at 2444.043 kb on - strand, within Rv2181at 2444.189 kb on - strand, within Rv2181at 2444.189 kb on - strand, within Rv2181

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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2,442,460 + Rv2180c 0.15 -0.5
2,442,460 + Rv2180c 0.15 -0.6
2,442,460 + Rv2180c 0.15 -0.3
2,442,460 + Rv2180c 0.15 +0.4
2,442,461 - Rv2180c 0.15 -0.3
2,442,461 - Rv2180c 0.15 +0.1
2,442,550 + Rv2180c 0.25 -1.5
2,442,551 - Rv2180c 0.25 +1.2
2,442,551 - Rv2180c 0.25 +1.2
2,442,771 + Rv2180c 0.50 +0.1
2,442,772 - Rv2180c 0.50 -0.1
2,442,851 - Rv2180c 0.59 +3.2
2,442,880 + Rv2180c 0.62 -1.2
2,442,880 + Rv2180c 0.62 +2.7
2,443,221 - -0.3
2,443,239 + +0.3
2,443,239 + +0.2
2,443,239 + -0.5
2,443,239 + -0.3
2,443,239 + +2.2
2,443,240 - +0.4
2,443,283 + +0.4
2,443,286 + +0.7
2,443,287 - -0.4
2,443,395 + -0.6
2,443,395 + -0.7
2,443,450 - Rv2181 0.12 -0.9
2,443,491 + Rv2181 0.15 -0.9
2,443,545 + Rv2181 0.19 +0.3
2,443,545 + Rv2181 0.19 -1.1
2,443,545 + Rv2181 0.19 -0.4
2,443,546 - Rv2181 0.19 -1.6
2,443,624 + Rv2181 0.25 -0.4
2,443,625 - Rv2181 0.25 -1.2
2,444,032 - Rv2181 0.57 -1.0
2,444,042 + Rv2181 0.58 -0.7
2,444,043 - Rv2181 0.58 -1.5
2,444,189 - Rv2181 0.69 -0.8
2,444,189 - Rv2181 0.69 -0.5

Or see this region's nucleotide sequence