Experiment: no stress control
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv2231A and Rv2231B are separated by 45 nucleotides Rv2231B and Rv2232 overlap by 106 nucleotides Rv2232 and Rv2234 overlap by 8 nucleotides Rv2234 and Rv2235 overlap by 1 nucleotides Rv2235 and Rv2236c overlap by 19 nucleotides
Rv2231A: Rv2231A - Possible toxin VapC16, at 2,505,736 to 2,506,161
Rv2231A
Rv2231B: Rv2231B - Possible antitoxin VapB16, at 2,506,207 to 2,506,383
Rv2231B
Rv2232: Rv2232 - Protein tyrosine kinase transcriptional regulatory protein PtkA, at 2,506,278 to 2,507,153
Rv2232
Rv2234: Rv2234 - Phosphotyrosine protein phosphatase PtpA (protein-tyrosine-phosphatase) (PTPase) (LMW phosphatase), at 2,507,146 to 2,507,637
Rv2234
Rv2235: Rv2235 - Probable conserved transmembrane protein, at 2,507,637 to 2,508,452
Rv2235
Rv2236c: Rv2236c - Probable cobalamin biosynthesis transmembrane protein CobD, at 2,508,434 to 2,509,375
Rv2236c
Position (kb)
2507
2508 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 2506.371 kb on - strand at 2506.570 kb on + strand, within Rv2232 at 2506.708 kb on + strand, within Rv2232 at 2507.144 kb on - strand at 2507.179 kb on - strand at 2507.294 kb on + strand, within Rv2234 at 2507.294 kb on + strand, within Rv2234 at 2507.528 kb on - strand, within Rv2234 at 2507.528 kb on - strand, within Rv2234 at 2507.530 kb on + strand, within Rv2234 at 2508.451 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction no stress control remove 2,506,371 - +1.4 2,506,570 + Rv2232 0.33 -0.2 2,506,708 + Rv2232 0.49 +0.4 2,507,144 - +2.2 2,507,179 - +0.1 2,507,294 + Rv2234 0.30 -1.7 2,507,294 + Rv2234 0.30 -2.5 2,507,528 - Rv2234 0.78 +0.0 2,507,528 - Rv2234 0.78 +1.2 2,507,530 + Rv2234 0.78 -1.4 2,508,451 - +0.1
Or see this region's nucleotide sequence