Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1640c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1639c and Rv1640c are separated by 58 nucleotidesRv1640c and Rv1641 are separated by 237 nucleotidesRv1641 and Rv1642 are separated by 49 nucleotides Rv1639c: Rv1639c - Conserved hypothetical membrane protein, at 1,846,989 to 1,848,458 Rv1639c Rv1640c: Rv1640c - Lysyl-tRNA synthetase 2 LysX, at 1,848,517 to 1,852,035 Rv1640c Rv1641: Rv1641 - Probable initiation factor if-3 InfC, at 1,852,273 to 1,852,878 Rv1641 Rv1642: Rv1642 - 50S ribosomal protein L35 RpmI, at 1,852,928 to 1,853,122 Rv1642 Position (kb) 1848 1849 1850 1851 1852 1853Strain fitness (log2 ratio) -3 -2 -1 0 1 2at 1847.576 kb on - strand, within Rv1639cat 1847.674 kb on - strand, within Rv1639cat 1847.858 kb on - strand, within Rv1639cat 1848.038 kb on - strand, within Rv1639cat 1848.232 kb on + strand, within Rv1639cat 1848.233 kb on - strand, within Rv1639cat 1848.233 kb on - strand, within Rv1639cat 1848.396 kb on + strandat 1848.397 kb on - strandat 1848.397 kb on - strandat 1848.629 kb on + strandat 1848.629 kb on + strandat 1848.629 kb on + strandat 1848.630 kb on - strandat 1848.861 kb on - strandat 1848.861 kb on - strandat 1849.221 kb on - strand, within Rv1640cat 1849.231 kb on + strand, within Rv1640cat 1849.374 kb on - strand, within Rv1640cat 1849.596 kb on + strand, within Rv1640cat 1849.620 kb on + strand, within Rv1640cat 1849.831 kb on + strand, within Rv1640cat 1849.831 kb on + strand, within Rv1640cat 1850.225 kb on + strand, within Rv1640cat 1850.249 kb on + strand, within Rv1640cat 1850.249 kb on + strand, within Rv1640cat 1850.445 kb on + strand, within Rv1640cat 1850.907 kb on - strand, within Rv1640cat 1851.009 kb on - strand, within Rv1640cat 1851.009 kb on - strand, within Rv1640cat 1851.016 kb on - strand, within Rv1640cat 1851.016 kb on - strand, within Rv1640cat 1851.163 kb on + strand, within Rv1640cat 1851.300 kb on - strand, within Rv1640cat 1851.322 kb on + strand, within Rv1640cat 1851.574 kb on - strand, within Rv1640cat 1851.684 kb on - strandat 1851.749 kb on - strandat 1851.866 kb on - strandat 1851.907 kb on + strandat 1851.908 kb on - strandat 1851.958 kb on - strandat 1851.979 kb on - strandat 1852.876 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,847,576 - Rv1639c 0.40 -0.3
1,847,674 - Rv1639c 0.47 +2.2
1,847,858 - Rv1639c 0.59 -1.8
1,848,038 - Rv1639c 0.71 -1.2
1,848,232 + Rv1639c 0.85 -0.5
1,848,233 - Rv1639c 0.85 -1.0
1,848,233 - Rv1639c 0.85 -2.4
1,848,396 + -0.2
1,848,397 - -0.6
1,848,397 - -1.8
1,848,629 + -0.6
1,848,629 + +0.6
1,848,629 + -0.1
1,848,630 - +0.3
1,848,861 - -0.1
1,848,861 - -0.4
1,849,221 - Rv1640c 0.20 -0.2
1,849,231 + Rv1640c 0.20 -0.3
1,849,374 - Rv1640c 0.24 +1.2
1,849,596 + Rv1640c 0.31 -1.0
1,849,620 + Rv1640c 0.31 -1.4
1,849,831 + Rv1640c 0.37 -1.2
1,849,831 + Rv1640c 0.37 +0.2
1,850,225 + Rv1640c 0.49 -0.7
1,850,249 + Rv1640c 0.49 -2.8
1,850,249 + Rv1640c 0.49 -1.2
1,850,445 + Rv1640c 0.55 +0.5
1,850,907 - Rv1640c 0.68 +1.4
1,851,009 - Rv1640c 0.71 -0.6
1,851,009 - Rv1640c 0.71 +0.6
1,851,016 - Rv1640c 0.71 +0.2
1,851,016 - Rv1640c 0.71 +1.3
1,851,163 + Rv1640c 0.75 -1.6
1,851,300 - Rv1640c 0.79 -1.6
1,851,322 + Rv1640c 0.80 -0.8
1,851,574 - Rv1640c 0.87 +1.8
1,851,684 - +0.4
1,851,749 - -1.0
1,851,866 - -1.2
1,851,907 + -1.7
1,851,908 - -0.7
1,851,958 - -0.9
1,851,979 - -0.0
1,852,876 + +1.4

Or see this region's nucleotide sequence