Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1388

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1387 and Rv1388 are separated by 305 nucleotidesRv1388 and Rv1389 are separated by 134 nucleotidesRv1389 and Rv1390 are separated by 65 nucleotides Rv1387: Rv1387 - PPE family protein PPE20, at 1,561,769 to 1,563,388 Rv1387 Rv1388: Rv1388 - Putative integration host factor MihF, at 1,563,694 to 1,564,266 Rv1388 Rv1389: Rv1389 - Probable guanylate kinase Gmk, at 1,564,401 to 1,565,027 Rv1389 Rv1390: Rv1390 - Probable DNA-directed RNA polymerase (omega chain) RpoZ (transcriptase omega chain) (RNA polymerase omega subunit), at 1,565,093 to 1,565,425 Rv1390 Position (kb) 1563 1564 1565Strain fitness (log2 ratio) -2 -1 0 1 2at 1562.727 kb on + strand, within Rv1387at 1562.727 kb on + strand, within Rv1387at 1562.727 kb on + strand, within Rv1387at 1562.727 kb on + strand, within Rv1387at 1562.727 kb on + strand, within Rv1387at 1562.728 kb on - strand, within Rv1387at 1562.728 kb on - strand, within Rv1387at 1562.728 kb on - strand, within Rv1387at 1562.728 kb on - strand, within Rv1387at 1562.728 kb on - strand, within Rv1387at 1562.746 kb on - strand, within Rv1387at 1562.825 kb on - strand, within Rv1387at 1562.966 kb on + strand, within Rv1387at 1562.967 kb on - strand, within Rv1387at 1562.967 kb on - strand, within Rv1387at 1562.994 kb on + strand, within Rv1387at 1562.994 kb on + strand, within Rv1387at 1562.995 kb on - strand, within Rv1387at 1563.236 kb on - strandat 1563.438 kb on + strandat 1563.438 kb on + strandat 1563.439 kb on - strandat 1563.487 kb on + strandat 1563.488 kb on - strandat 1563.488 kb on - strandat 1565.041 kb on + strandat 1565.048 kb on + strandat 1565.048 kb on + strandat 1565.048 kb on + strandat 1565.052 kb on + strandat 1565.052 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,562,727 + Rv1387 0.59 -0.6
1,562,727 + Rv1387 0.59 -0.2
1,562,727 + Rv1387 0.59 -0.2
1,562,727 + Rv1387 0.59 +0.1
1,562,727 + Rv1387 0.59 -1.0
1,562,728 - Rv1387 0.59 -0.2
1,562,728 - Rv1387 0.59 -0.5
1,562,728 - Rv1387 0.59 +0.0
1,562,728 - Rv1387 0.59 -0.3
1,562,728 - Rv1387 0.59 -0.4
1,562,746 - Rv1387 0.60 -0.5
1,562,825 - Rv1387 0.65 +0.4
1,562,966 + Rv1387 0.74 +0.7
1,562,967 - Rv1387 0.74 +0.1
1,562,967 - Rv1387 0.74 +0.6
1,562,994 + Rv1387 0.76 +0.7
1,562,994 + Rv1387 0.76 -0.2
1,562,995 - Rv1387 0.76 -1.5
1,563,236 - -0.8
1,563,438 + -0.4
1,563,438 + -0.0
1,563,439 - +2.2
1,563,487 + +1.2
1,563,488 - +0.2
1,563,488 - -0.2
1,565,041 + +0.6
1,565,048 + -0.4
1,565,048 + +1.0
1,565,048 + +0.1
1,565,052 + -0.2
1,565,052 + -1.9

Or see this region's nucleotide sequence