Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1278

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1277 and Rv1278 overlap by 4 nucleotidesRv1278 and Rv1279 are separated by 20 nucleotides Rv1277: Rv1277 - Conserved hypothetical protein, at 1,426,164 to 1,427,417 Rv1277 Rv1278: Rv1278 - Hypothetical protein, at 1,427,414 to 1,430,041 Rv1278 Rv1279: Rv1279 - Probable dehydrogenase FAD flavoprotein GMC oxidoreductase, at 1,430,062 to 1,431,648 Rv1279 Position (kb) 1427 1428 1429 1430 1431Strain fitness (log2 ratio) -2 -1 0 1at 1426.414 kb on + strand, within Rv1277at 1426.459 kb on + strand, within Rv1277at 1426.506 kb on + strand, within Rv1277at 1426.840 kb on - strand, within Rv1277at 1426.868 kb on + strand, within Rv1277at 1426.960 kb on + strand, within Rv1277at 1427.039 kb on + strand, within Rv1277at 1427.255 kb on - strand, within Rv1277at 1427.562 kb on - strandat 1427.954 kb on + strand, within Rv1278at 1428.133 kb on - strand, within Rv1278at 1428.133 kb on - strand, within Rv1278at 1428.591 kb on + strand, within Rv1278at 1428.591 kb on + strand, within Rv1278at 1428.591 kb on + strand, within Rv1278at 1428.592 kb on - strand, within Rv1278at 1429.206 kb on + strand, within Rv1278at 1429.778 kb on + strand, within Rv1278at 1430.034 kb on + strandat 1430.034 kb on + strandat 1430.035 kb on - strandat 1430.081 kb on - strandat 1430.081 kb on - strandat 1430.081 kb on - strandat 1430.081 kb on - strandat 1430.248 kb on + strand, within Rv1279at 1431.026 kb on - strand, within Rv1279at 1431.029 kb on + strand, within Rv1279at 1431.030 kb on - strand, within Rv1279at 1431.030 kb on - strand, within Rv1279at 1431.030 kb on - strand, within Rv1279

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,426,414 + Rv1277 0.20 -0.8
1,426,459 + Rv1277 0.24 -0.7
1,426,506 + Rv1277 0.27 -0.8
1,426,840 - Rv1277 0.54 -0.5
1,426,868 + Rv1277 0.56 +1.5
1,426,960 + Rv1277 0.63 -1.8
1,427,039 + Rv1277 0.70 -0.1
1,427,255 - Rv1277 0.87 -0.8
1,427,562 - +1.3
1,427,954 + Rv1278 0.21 -0.3
1,428,133 - Rv1278 0.27 -2.1
1,428,133 - Rv1278 0.27 -0.7
1,428,591 + Rv1278 0.45 +0.3
1,428,591 + Rv1278 0.45 -0.5
1,428,591 + Rv1278 0.45 -0.8
1,428,592 - Rv1278 0.45 -1.9
1,429,206 + Rv1278 0.68 -0.7
1,429,778 + Rv1278 0.90 -1.5
1,430,034 + +0.7
1,430,034 + -0.2
1,430,035 - -0.7
1,430,081 - +0.1
1,430,081 - -2.1
1,430,081 - -1.0
1,430,081 - -1.6
1,430,248 + Rv1279 0.12 +0.1
1,431,026 - Rv1279 0.61 -1.5
1,431,029 + Rv1279 0.61 -0.1
1,431,030 - Rv1279 0.61 +0.3
1,431,030 - Rv1279 0.61 -1.4
1,431,030 - Rv1279 0.61 -0.9

Or see this region's nucleotide sequence