Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1258c

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1257c and Rv1258c overlap by 4 nucleotidesRv1258c and Rv1259 overlap by 2 nucleotidesRv1259 and Rv1260 are separated by 1 nucleotides Rv1257c: Rv1257c - Probable oxidoreductase, at 1,404,717 to 1,406,084 Rv1257c Rv1258c: Rv1258c - Probable conserved integral membrane transport protein, at 1,406,081 to 1,407,340 Rv1258c Rv1259: Rv1259 - Probable uracil DNA glycosylase, UdgB, at 1,407,339 to 1,408,238 Rv1259 Rv1260: Rv1260 - Probable oxidoreductase, at 1,408,240 to 1,409,358 Rv1260 Position (kb) 1406 1407 1408Strain fitness (log2 ratio) -2 -1 0 1 2 3at 1405.596 kb on + strand, within Rv1257cat 1405.596 kb on + strand, within Rv1257cat 1405.597 kb on - strand, within Rv1257cat 1405.597 kb on - strand, within Rv1257cat 1405.601 kb on - strand, within Rv1257cat 1405.619 kb on - strand, within Rv1257cat 1405.747 kb on + strand, within Rv1257cat 1405.748 kb on - strand, within Rv1257cat 1406.017 kb on + strandat 1406.298 kb on - strand, within Rv1258cat 1406.334 kb on - strand, within Rv1258cat 1406.334 kb on - strand, within Rv1258cat 1406.340 kb on + strand, within Rv1258cat 1406.340 kb on + strand, within Rv1258cat 1406.341 kb on - strand, within Rv1258cat 1406.341 kb on - strand, within Rv1258cat 1406.341 kb on - strand, within Rv1258cat 1406.344 kb on + strand, within Rv1258cat 1406.344 kb on + strand, within Rv1258cat 1406.345 kb on - strand, within Rv1258cat 1406.345 kb on - strand, within Rv1258cat 1406.345 kb on - strand, within Rv1258cat 1406.347 kb on - strand, within Rv1258cat 1406.347 kb on - strand, within Rv1258cat 1406.367 kb on + strand, within Rv1258cat 1406.368 kb on - strand, within Rv1258cat 1406.508 kb on + strand, within Rv1258cat 1406.626 kb on - strand, within Rv1258cat 1406.626 kb on - strand, within Rv1258cat 1406.812 kb on + strand, within Rv1258cat 1406.813 kb on - strand, within Rv1258cat 1406.878 kb on + strand, within Rv1258cat 1406.878 kb on + strand, within Rv1258cat 1407.138 kb on + strand, within Rv1258cat 1407.260 kb on + strandat 1407.344 kb on + strandat 1407.344 kb on + strandat 1407.345 kb on - strandat 1407.825 kb on - strand, within Rv1259at 1408.140 kb on + strand, within Rv1259at 1408.161 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,405,596 + Rv1257c 0.64 +0.8
1,405,596 + Rv1257c 0.64 -0.3
1,405,597 - Rv1257c 0.64 +0.1
1,405,597 - Rv1257c 0.64 -1.7
1,405,601 - Rv1257c 0.65 -0.0
1,405,619 - Rv1257c 0.66 +0.2
1,405,747 + Rv1257c 0.75 -1.0
1,405,748 - Rv1257c 0.75 -0.3
1,406,017 + -0.6
1,406,298 - Rv1258c 0.17 +0.4
1,406,334 - Rv1258c 0.20 -0.2
1,406,334 - Rv1258c 0.20 -0.1
1,406,340 + Rv1258c 0.21 -1.7
1,406,340 + Rv1258c 0.21 -0.4
1,406,341 - Rv1258c 0.21 +0.4
1,406,341 - Rv1258c 0.21 +0.0
1,406,341 - Rv1258c 0.21 -1.2
1,406,344 + Rv1258c 0.21 -0.6
1,406,344 + Rv1258c 0.21 +0.8
1,406,345 - Rv1258c 0.21 -1.0
1,406,345 - Rv1258c 0.21 -1.0
1,406,345 - Rv1258c 0.21 -0.7
1,406,347 - Rv1258c 0.21 -0.6
1,406,347 - Rv1258c 0.21 -0.3
1,406,367 + Rv1258c 0.23 -1.9
1,406,368 - Rv1258c 0.23 -0.8
1,406,508 + Rv1258c 0.34 -0.2
1,406,626 - Rv1258c 0.43 +0.8
1,406,626 - Rv1258c 0.43 -0.4
1,406,812 + Rv1258c 0.58 -0.5
1,406,813 - Rv1258c 0.58 -0.1
1,406,878 + Rv1258c 0.63 -0.1
1,406,878 + Rv1258c 0.63 +1.6
1,407,138 + Rv1258c 0.84 -1.0
1,407,260 + -0.6
1,407,344 + -0.4
1,407,344 + +0.5
1,407,345 - -0.0
1,407,825 - Rv1259 0.54 +2.2
1,408,140 + Rv1259 0.89 +3.7
1,408,161 - +0.5

Or see this region's nucleotide sequence