Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1001

Experiment: no stress control

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0999 and Rv1000c are separated by 5 nucleotidesRv1000c and Rv1001 are separated by 36 nucleotidesRv1001 and Rv1002c are separated by 34 nucleotides Rv0999: Rv0999 - Unknown protein, at 1,115,767 to 1,116,525 Rv0999 Rv1000c: Rv1000c - Conserved hypothetical protein, at 1,116,531 to 1,117,148 Rv1000c Rv1001: Rv1001 - Probable arginine deiminase ArcA (adi) (ad) (arginine dihydrolase), at 1,117,185 to 1,118,393 Rv1001 Rv1002c: Rv1002c - Conserved membrane protein, at 1,118,428 to 1,119,939 Rv1002c Position (kb) 1117 1118 1119Strain fitness (log2 ratio) -2 -1 0 1 2at 1116.296 kb on + strand, within Rv0999at 1116.297 kb on - strand, within Rv0999at 1116.383 kb on - strand, within Rv0999at 1116.388 kb on + strand, within Rv0999at 1116.389 kb on - strand, within Rv0999at 1116.497 kb on + strandat 1116.532 kb on + strandat 1116.642 kb on + strand, within Rv1000cat 1116.643 kb on - strand, within Rv1000cat 1116.741 kb on - strand, within Rv1000cat 1116.809 kb on - strand, within Rv1000cat 1116.811 kb on + strand, within Rv1000cat 1116.812 kb on - strand, within Rv1000cat 1116.856 kb on + strand, within Rv1000cat 1116.856 kb on + strand, within Rv1000cat 1116.857 kb on - strand, within Rv1000cat 1116.964 kb on + strand, within Rv1000cat 1116.965 kb on - strand, within Rv1000cat 1116.965 kb on - strand, within Rv1000cat 1117.225 kb on + strandat 1117.226 kb on - strandat 1117.414 kb on + strand, within Rv1001at 1117.515 kb on - strand, within Rv1001at 1117.613 kb on + strand, within Rv1001at 1117.721 kb on - strand, within Rv1001at 1117.761 kb on + strand, within Rv1001at 1117.761 kb on + strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.762 kb on - strand, within Rv1001at 1117.800 kb on + strand, within Rv1001at 1118.021 kb on + strand, within Rv1001at 1118.022 kb on - strand, within Rv1001at 1118.269 kb on + strand, within Rv1001at 1118.270 kb on - strand, within Rv1001at 1118.270 kb on - strand, within Rv1001at 1118.392 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction no stress control
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1,116,296 + Rv0999 0.70 +0.6
1,116,297 - Rv0999 0.70 +0.6
1,116,383 - Rv0999 0.81 +2.1
1,116,388 + Rv0999 0.82 -0.9
1,116,389 - Rv0999 0.82 -0.2
1,116,497 + +0.2
1,116,532 + -0.3
1,116,642 + Rv1000c 0.18 +0.4
1,116,643 - Rv1000c 0.18 -2.1
1,116,741 - Rv1000c 0.34 -0.5
1,116,809 - Rv1000c 0.45 -0.1
1,116,811 + Rv1000c 0.45 +1.5
1,116,812 - Rv1000c 0.45 -0.8
1,116,856 + Rv1000c 0.53 -1.3
1,116,856 + Rv1000c 0.53 -0.6
1,116,857 - Rv1000c 0.53 +0.7
1,116,964 + Rv1000c 0.70 -0.1
1,116,965 - Rv1000c 0.70 -1.1
1,116,965 - Rv1000c 0.70 -0.8
1,117,225 + +1.0
1,117,226 - -0.1
1,117,414 + Rv1001 0.19 +1.8
1,117,515 - Rv1001 0.27 +2.1
1,117,613 + Rv1001 0.35 +0.2
1,117,721 - Rv1001 0.44 -0.6
1,117,761 + Rv1001 0.48 -1.0
1,117,761 + Rv1001 0.48 -1.3
1,117,762 - Rv1001 0.48 +0.1
1,117,762 - Rv1001 0.48 +2.1
1,117,762 - Rv1001 0.48 -0.8
1,117,762 - Rv1001 0.48 -1.2
1,117,762 - Rv1001 0.48 -1.3
1,117,800 + Rv1001 0.51 +0.3
1,118,021 + Rv1001 0.69 +0.9
1,118,022 - Rv1001 0.69 -1.0
1,118,269 + Rv1001 0.90 -1.1
1,118,270 - Rv1001 0.90 -1.1
1,118,270 - Rv1001 0.90 -0.6
1,118,392 - -0.2

Or see this region's nucleotide sequence