Experiment: Survival; Treatment=FW300; TreatmentDuration=2hrs; Outgrowth=R2A_Kan10_Lactate
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt ABCV34_RS11230 and ABCV34_RS11235 are separated by 67 nucleotides ABCV34_RS11235 and ABCV34_RS11240 are separated by 58 nucleotides ABCV34_RS11240 and ABCV34_RS11245 are separated by 45 nucleotides ABCV34_RS11245 and ABCV34_RS11250 overlap by 4 nucleotides
ABCV34_RS11230: ABCV34_RS11230 - histidinol dehydrogenase, at 2,391,763 to 2,393,070
_RS11230
ABCV34_RS11235: ABCV34_RS11235 - imidazoleglycerol-phosphate dehydratase HisB, at 2,393,138 to 2,393,725
_RS11235
ABCV34_RS11240: ABCV34_RS11240 - imidazole glycerol phosphate synthase subunit HisH, at 2,393,784 to 2,394,497
_RS11240
ABCV34_RS11245: ABCV34_RS11245 - 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase, at 2,394,543 to 2,395,373
_RS11245
ABCV34_RS11250: ABCV34_RS11250 - imidazole glycerol phosphate synthase subunit HisF, at 2,395,370 to 2,396,176
_RS11250
Position (kb)
2393
2394
2395 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 2392.832 kb on - strand, within ABCV34_RS11230 at 2392.855 kb on + strand, within ABCV34_RS11230 at 2392.856 kb on - strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.877 kb on + strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.878 kb on - strand, within ABCV34_RS11230 at 2392.924 kb on + strand, within ABCV34_RS11230 at 2392.924 kb on + strand, within ABCV34_RS11230 at 2392.924 kb on + strand, within ABCV34_RS11230 at 2392.924 kb on + strand, within ABCV34_RS11230 at 2392.925 kb on - strand, within ABCV34_RS11230 at 2392.925 kb on - strand, within ABCV34_RS11230 at 2392.925 kb on - strand, within ABCV34_RS11230 at 2393.206 kb on + strand, within ABCV34_RS11235 at 2393.420 kb on + strand, within ABCV34_RS11235 at 2393.420 kb on + strand, within ABCV34_RS11235 at 2393.420 kb on + strand, within ABCV34_RS11235 at 2393.420 kb on + strand, within ABCV34_RS11235 at 2393.421 kb on - strand, within ABCV34_RS11235 at 2393.421 kb on - strand, within ABCV34_RS11235 at 2393.421 kb on - strand, within ABCV34_RS11235 at 2393.421 kb on - strand, within ABCV34_RS11235 at 2393.486 kb on + strand, within ABCV34_RS11235 at 2393.486 kb on + strand, within ABCV34_RS11235 at 2393.486 kb on + strand, within ABCV34_RS11235 at 2393.487 kb on - strand, within ABCV34_RS11235 at 2393.487 kb on - strand, within ABCV34_RS11235 at 2393.487 kb on - strand, within ABCV34_RS11235 at 2393.487 kb on - strand, within ABCV34_RS11235 at 2393.498 kb on + strand, within ABCV34_RS11235 at 2393.498 kb on + strand, within ABCV34_RS11235 at 2393.498 kb on + strand, within ABCV34_RS11235 at 2393.498 kb on + strand, within ABCV34_RS11235 at 2393.498 kb on + strand, within ABCV34_RS11235 at 2393.498 kb on + strand, within ABCV34_RS11235 at 2393.498 kb on + strand, within ABCV34_RS11235 at 2393.499 kb on - strand, within ABCV34_RS11235 at 2393.499 kb on - strand, within ABCV34_RS11235 at 2393.499 kb on - strand, within ABCV34_RS11235 at 2393.499 kb on - strand, within ABCV34_RS11235 at 2393.499 kb on - strand, within ABCV34_RS11235 at 2393.499 kb on - strand, within ABCV34_RS11235 at 2393.710 kb on + strand at 2393.710 kb on + strand at 2393.711 kb on - strand at 2393.819 kb on + strand at 2393.967 kb on - strand, within ABCV34_RS11240 at 2393.967 kb on - strand, within ABCV34_RS11240 at 2394.312 kb on + strand, within ABCV34_RS11240 at 2394.312 kb on + strand, within ABCV34_RS11240 at 2394.312 kb on + strand, within ABCV34_RS11240 at 2394.312 kb on + strand, within ABCV34_RS11240 at 2394.313 kb on - strand, within ABCV34_RS11240 at 2394.313 kb on - strand, within ABCV34_RS11240 at 2394.313 kb on - strand, within ABCV34_RS11240 at 2394.327 kb on + strand, within ABCV34_RS11240 at 2394.327 kb on + strand, within ABCV34_RS11240 at 2394.327 kb on + strand, within ABCV34_RS11240 at 2394.327 kb on + strand, within ABCV34_RS11240 at 2394.327 kb on + strand, within ABCV34_RS11240 at 2394.328 kb on - strand, within ABCV34_RS11240 at 2394.328 kb on - strand, within ABCV34_RS11240 at 2394.328 kb on - strand, within ABCV34_RS11240 at 2394.328 kb on - strand, within ABCV34_RS11240 at 2394.328 kb on - strand, within ABCV34_RS11240 at 2394.328 kb on - strand, within ABCV34_RS11240 at 2394.330 kb on + strand, within ABCV34_RS11240 at 2394.330 kb on + strand, within ABCV34_RS11240 at 2394.331 kb on - strand, within ABCV34_RS11240 at 2394.331 kb on - strand, within ABCV34_RS11240 at 2394.331 kb on - strand, within ABCV34_RS11240 at 2394.331 kb on - strand, within ABCV34_RS11240 at 2394.331 kb on - strand, within ABCV34_RS11240 at 2394.413 kb on + strand, within ABCV34_RS11240 at 2394.413 kb on + strand, within ABCV34_RS11240 at 2394.414 kb on - strand, within ABCV34_RS11240 at 2394.414 kb on - strand, within ABCV34_RS11240 at 2394.468 kb on + strand at 2394.468 kb on + strand at 2394.469 kb on - strand at 2394.469 kb on - strand at 2394.469 kb on - strand at 2394.469 kb on - strand at 2394.469 kb on - strand at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.819 kb on + strand, within ABCV34_RS11245 at 2394.820 kb on - strand, within ABCV34_RS11245 at 2394.820 kb on - strand, within ABCV34_RS11245 at 2394.822 kb on + strand, within ABCV34_RS11245 at 2394.822 kb on + strand, within ABCV34_RS11245 at 2394.822 kb on + strand, within ABCV34_RS11245 at 2394.822 kb on + strand, within ABCV34_RS11245 at 2394.823 kb on - strand, within ABCV34_RS11245 at 2394.823 kb on - strand, within ABCV34_RS11245 at 2394.823 kb on - strand, within ABCV34_RS11245 at 2394.823 kb on - strand, within ABCV34_RS11245 at 2394.823 kb on - strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.843 kb on + strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.844 kb on - strand, within ABCV34_RS11245 at 2394.846 kb on - strand, within ABCV34_RS11245 at 2395.020 kb on + strand, within ABCV34_RS11245 at 2395.021 kb on - strand, within ABCV34_RS11245 at 2395.021 kb on - strand, within ABCV34_RS11245 at 2395.041 kb on + strand, within ABCV34_RS11245 at 2395.041 kb on + strand, within ABCV34_RS11245 at 2395.041 kb on + strand, within ABCV34_RS11245 at 2395.041 kb on + strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.042 kb on - strand, within ABCV34_RS11245 at 2395.144 kb on + strand, within ABCV34_RS11245 at 2395.144 kb on + strand, within ABCV34_RS11245 at 2395.144 kb on + strand, within ABCV34_RS11245 at 2395.144 kb on + strand, within ABCV34_RS11245 at 2395.144 kb on + strand, within ABCV34_RS11245 at 2395.144 kb on + strand, within ABCV34_RS11245 at 2395.145 kb on - strand, within ABCV34_RS11245 at 2395.145 kb on - strand, within ABCV34_RS11245 at 2395.145 kb on - strand, within ABCV34_RS11245 at 2395.145 kb on - strand, within ABCV34_RS11245 at 2395.145 kb on - strand, within ABCV34_RS11245 at 2395.145 kb on - strand, within ABCV34_RS11245 at 2395.224 kb on + strand, within ABCV34_RS11245 at 2395.224 kb on + strand, within ABCV34_RS11245 at 2395.224 kb on + strand, within ABCV34_RS11245 at 2395.224 kb on + strand, within ABCV34_RS11245 at 2395.225 kb on - strand, within ABCV34_RS11245 at 2395.225 kb on - strand, within ABCV34_RS11245
Per-strain Table
Position Strand Gene LocusTag Fraction Survival; Treatment=FW300; TreatmentDuration=2hrs; Outgrowth=R2A_Kan10_Lactate remove 2,392,832 - ABCV34_RS11230 0.82 +3.5 2,392,855 + ABCV34_RS11230 0.83 -1.3 2,392,856 - ABCV34_RS11230 0.84 -0.5 2,392,877 + ABCV34_RS11230 0.85 -0.6 2,392,877 + ABCV34_RS11230 0.85 -0.6 2,392,877 + ABCV34_RS11230 0.85 -1.0 2,392,877 + ABCV34_RS11230 0.85 -0.7 2,392,877 + ABCV34_RS11230 0.85 -0.3 2,392,877 + ABCV34_RS11230 0.85 -2.5 2,392,877 + ABCV34_RS11230 0.85 +1.2 2,392,877 + ABCV34_RS11230 0.85 -2.5 2,392,878 - ABCV34_RS11230 0.85 -0.6 2,392,878 - ABCV34_RS11230 0.85 +0.3 2,392,878 - ABCV34_RS11230 0.85 +0.3 2,392,878 - ABCV34_RS11230 0.85 -1.2 2,392,878 - ABCV34_RS11230 0.85 -0.7 2,392,878 - ABCV34_RS11230 0.85 +0.5 2,392,878 - ABCV34_RS11230 0.85 -1.6 2,392,878 - ABCV34_RS11230 0.85 -0.9 2,392,878 - ABCV34_RS11230 0.85 -0.9 2,392,878 - ABCV34_RS11230 0.85 -1.1 2,392,878 - ABCV34_RS11230 0.85 -1.1 2,392,878 - ABCV34_RS11230 0.85 -0.7 2,392,878 - ABCV34_RS11230 0.85 -1.3 2,392,878 - ABCV34_RS11230 0.85 -2.6 2,392,878 - ABCV34_RS11230 0.85 -0.3 2,392,878 - ABCV34_RS11230 0.85 +0.6 2,392,878 - ABCV34_RS11230 0.85 -1.6 2,392,878 - ABCV34_RS11230 0.85 -1.6 2,392,878 - ABCV34_RS11230 0.85 -1.6 2,392,924 + ABCV34_RS11230 0.89 +1.9 2,392,924 + ABCV34_RS11230 0.89 -1.4 2,392,924 + ABCV34_RS11230 0.89 -0.6 2,392,924 + ABCV34_RS11230 0.89 -0.9 2,392,925 - ABCV34_RS11230 0.89 -1.0 2,392,925 - ABCV34_RS11230 0.89 -1.3 2,392,925 - ABCV34_RS11230 0.89 -1.2 2,393,206 + ABCV34_RS11235 0.12 -0.7 2,393,420 + ABCV34_RS11235 0.48 -0.7 2,393,420 + ABCV34_RS11235 0.48 +1.9 2,393,420 + ABCV34_RS11235 0.48 -1.8 2,393,420 + ABCV34_RS11235 0.48 -0.1 2,393,421 - ABCV34_RS11235 0.48 +1.0 2,393,421 - ABCV34_RS11235 0.48 -1.1 2,393,421 - ABCV34_RS11235 0.48 -1.5 2,393,421 - ABCV34_RS11235 0.48 +1.0 2,393,486 + ABCV34_RS11235 0.59 +1.9 2,393,486 + ABCV34_RS11235 0.59 +3.1 2,393,486 + ABCV34_RS11235 0.59 -1.8 2,393,487 - ABCV34_RS11235 0.59 +0.1 2,393,487 - ABCV34_RS11235 0.59 -0.9 2,393,487 - ABCV34_RS11235 0.59 -0.5 2,393,487 - ABCV34_RS11235 0.59 -2.5 2,393,498 + ABCV34_RS11235 0.61 -1.6 2,393,498 + ABCV34_RS11235 0.61 -1.6 2,393,498 + ABCV34_RS11235 0.61 +0.3 2,393,498 + ABCV34_RS11235 0.61 -0.7 2,393,498 + ABCV34_RS11235 0.61 +0.9 2,393,498 + ABCV34_RS11235 0.61 -1.7 2,393,498 + ABCV34_RS11235 0.61 +1.3 2,393,499 - ABCV34_RS11235 0.61 -0.7 2,393,499 - ABCV34_RS11235 0.61 -1.6 2,393,499 - ABCV34_RS11235 0.61 +1.3 2,393,499 - ABCV34_RS11235 0.61 +0.9 2,393,499 - ABCV34_RS11235 0.61 -0.5 2,393,499 - ABCV34_RS11235 0.61 +0.3 2,393,710 + -0.1 2,393,710 + -0.8 2,393,711 - -0.7 2,393,819 + -1.7 2,393,967 - ABCV34_RS11240 0.26 +0.6 2,393,967 - ABCV34_RS11240 0.26 -0.7 2,394,312 + ABCV34_RS11240 0.74 -1.4 2,394,312 + ABCV34_RS11240 0.74 +1.1 2,394,312 + ABCV34_RS11240 0.74 -1.4 2,394,312 + ABCV34_RS11240 0.74 -1.3 2,394,313 - ABCV34_RS11240 0.74 -0.9 2,394,313 - ABCV34_RS11240 0.74 -1.5 2,394,313 - ABCV34_RS11240 0.74 -1.0 2,394,327 + ABCV34_RS11240 0.76 +0.3 2,394,327 + ABCV34_RS11240 0.76 -0.7 2,394,327 + ABCV34_RS11240 0.76 -1.3 2,394,327 + ABCV34_RS11240 0.76 -2.1 2,394,327 + ABCV34_RS11240 0.76 -1.0 2,394,328 - ABCV34_RS11240 0.76 -1.3 2,394,328 - ABCV34_RS11240 0.76 -0.5 2,394,328 - ABCV34_RS11240 0.76 -2.7 2,394,328 - ABCV34_RS11240 0.76 +0.4 2,394,328 - ABCV34_RS11240 0.76 +1.3 2,394,328 - ABCV34_RS11240 0.76 +0.9 2,394,330 + ABCV34_RS11240 0.76 -1.8 2,394,330 + ABCV34_RS11240 0.76 -1.6 2,394,331 - ABCV34_RS11240 0.77 -1.3 2,394,331 - ABCV34_RS11240 0.77 +0.9 2,394,331 - ABCV34_RS11240 0.77 -0.1 2,394,331 - ABCV34_RS11240 0.77 -0.5 2,394,331 - ABCV34_RS11240 0.77 +0.0 2,394,413 + ABCV34_RS11240 0.88 +1.9 2,394,413 + ABCV34_RS11240 0.88 +1.9 2,394,414 - ABCV34_RS11240 0.88 -2.2 2,394,414 - ABCV34_RS11240 0.88 -0.7 2,394,468 + +1.3 2,394,468 + -0.8 2,394,469 - +1.9 2,394,469 - +1.4 2,394,469 - -2.5 2,394,469 - -1.3 2,394,469 - +0.1 2,394,819 + ABCV34_RS11245 0.33 +0.1 2,394,819 + ABCV34_RS11245 0.33 +0.6 2,394,819 + ABCV34_RS11245 0.33 -1.7 2,394,819 + ABCV34_RS11245 0.33 -0.4 2,394,819 + ABCV34_RS11245 0.33 -0.9 2,394,819 + ABCV34_RS11245 0.33 +0.9 2,394,819 + ABCV34_RS11245 0.33 -0.9 2,394,819 + ABCV34_RS11245 0.33 -0.1 2,394,819 + ABCV34_RS11245 0.33 +2.4 2,394,820 - ABCV34_RS11245 0.33 -0.5 2,394,820 - ABCV34_RS11245 0.33 -1.3 2,394,822 + ABCV34_RS11245 0.34 -2.2 2,394,822 + ABCV34_RS11245 0.34 -1.4 2,394,822 + ABCV34_RS11245 0.34 +0.3 2,394,822 + ABCV34_RS11245 0.34 -2.9 2,394,823 - ABCV34_RS11245 0.34 -1.6 2,394,823 - ABCV34_RS11245 0.34 +0.3 2,394,823 - ABCV34_RS11245 0.34 -0.1 2,394,823 - ABCV34_RS11245 0.34 -2.1 2,394,823 - ABCV34_RS11245 0.34 +0.9 2,394,843 + ABCV34_RS11245 0.36 -1.3 2,394,843 + ABCV34_RS11245 0.36 +0.5 2,394,843 + ABCV34_RS11245 0.36 +0.9 2,394,843 + ABCV34_RS11245 0.36 -2.3 2,394,843 + ABCV34_RS11245 0.36 -0.2 2,394,843 + ABCV34_RS11245 0.36 -0.1 2,394,843 + ABCV34_RS11245 0.36 -1.6 2,394,843 + ABCV34_RS11245 0.36 -1.5 2,394,844 - ABCV34_RS11245 0.36 -1.0 2,394,844 - ABCV34_RS11245 0.36 -2.1 2,394,844 - ABCV34_RS11245 0.36 +0.9 2,394,844 - ABCV34_RS11245 0.36 -0.5 2,394,844 - ABCV34_RS11245 0.36 +0.9 2,394,844 - ABCV34_RS11245 0.36 -0.9 2,394,844 - ABCV34_RS11245 0.36 -0.5 2,394,844 - ABCV34_RS11245 0.36 +0.9 2,394,844 - ABCV34_RS11245 0.36 +0.5 2,394,846 - ABCV34_RS11245 0.36 -1.4 2,395,020 + ABCV34_RS11245 0.57 -1.9 2,395,021 - ABCV34_RS11245 0.58 -0.1 2,395,021 - ABCV34_RS11245 0.58 -0.7 2,395,041 + ABCV34_RS11245 0.60 -2.0 2,395,041 + ABCV34_RS11245 0.60 +0.3 2,395,041 + ABCV34_RS11245 0.60 -0.2 2,395,041 + ABCV34_RS11245 0.60 +0.3 2,395,042 - ABCV34_RS11245 0.60 -1.7 2,395,042 - ABCV34_RS11245 0.60 +0.9 2,395,042 - ABCV34_RS11245 0.60 -1.3 2,395,042 - ABCV34_RS11245 0.60 +0.3 2,395,042 - ABCV34_RS11245 0.60 -0.8 2,395,042 - ABCV34_RS11245 0.60 -2.5 2,395,042 - ABCV34_RS11245 0.60 -0.9 2,395,042 - ABCV34_RS11245 0.60 -2.1 2,395,144 + ABCV34_RS11245 0.72 -2.0 2,395,144 + ABCV34_RS11245 0.72 +2.9 2,395,144 + ABCV34_RS11245 0.72 -1.7 2,395,144 + ABCV34_RS11245 0.72 -1.6 2,395,144 + ABCV34_RS11245 0.72 -0.4 2,395,144 + ABCV34_RS11245 0.72 +0.9 2,395,145 - ABCV34_RS11245 0.72 +0.3 2,395,145 - ABCV34_RS11245 0.72 -1.9 2,395,145 - ABCV34_RS11245 0.72 -0.9 2,395,145 - ABCV34_RS11245 0.72 -0.1 2,395,145 - ABCV34_RS11245 0.72 -1.1 2,395,145 - ABCV34_RS11245 0.72 -0.8 2,395,224 + ABCV34_RS11245 0.82 -1.6 2,395,224 + ABCV34_RS11245 0.82 -1.8 2,395,224 + ABCV34_RS11245 0.82 -1.6 2,395,224 + ABCV34_RS11245 0.82 -1.3 2,395,225 - ABCV34_RS11245 0.82 +0.9 2,395,225 - ABCV34_RS11245 0.82 -2.2
Or see this region's nucleotide sequence