Experiment: D-Cycloserine 0.032 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt ABZR86_RS18215 and ABZR86_RS18220 are separated by 168 nucleotides ABZR86_RS18220 and ABZR86_RS18225 overlap by 8 nucleotides ABZR86_RS18225 and ABZR86_RS18230 are separated by 172 nucleotides
ABZR86_RS18215: ABZR86_RS18215 - translesion error-prone DNA polymerase V autoproteolytic subunit, at 61,237 to 61,806
_RS18215
ABZR86_RS18220: ABZR86_RS18220 - hypothetical protein, at 61,975 to 62,403
_RS18220
ABZR86_RS18225: ABZR86_RS18225 - helix-turn-helix transcriptional regulator, at 62,396 to 62,608
_RS18225
ABZR86_RS18230: ABZR86_RS18230 - hypothetical protein, at 62,781 to 63,680
_RS18230
Position (kb)
62
63 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 61.459 kb on + strand, within ABZR86_RS18215 at 61.824 kb on + strand at 61.844 kb on + strand at 61.874 kb on - strand at 61.883 kb on + strand at 61.883 kb on + strand at 61.883 kb on + strand at 61.884 kb on - strand at 61.884 kb on - strand at 62.038 kb on + strand, within ABZR86_RS18220 at 62.039 kb on - strand, within ABZR86_RS18220 at 62.039 kb on - strand, within ABZR86_RS18220 at 62.185 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.236 kb on + strand, within ABZR86_RS18220 at 62.237 kb on - strand, within ABZR86_RS18220 at 62.237 kb on - strand, within ABZR86_RS18220 at 62.237 kb on - strand, within ABZR86_RS18220 at 62.237 kb on - strand, within ABZR86_RS18220 at 62.237 kb on - strand, within ABZR86_RS18220 at 62.242 kb on + strand, within ABZR86_RS18220 at 62.242 kb on + strand, within ABZR86_RS18220 at 62.242 kb on + strand, within ABZR86_RS18220 at 62.242 kb on + strand, within ABZR86_RS18220 at 62.242 kb on + strand, within ABZR86_RS18220 at 62.243 kb on - strand, within ABZR86_RS18220 at 62.243 kb on - strand, within ABZR86_RS18220 at 62.243 kb on - strand, within ABZR86_RS18220 at 62.245 kb on + strand, within ABZR86_RS18220 at 62.245 kb on + strand, within ABZR86_RS18220 at 62.245 kb on + strand, within ABZR86_RS18220 at 62.246 kb on - strand, within ABZR86_RS18220 at 62.246 kb on - strand, within ABZR86_RS18220 at 62.246 kb on - strand, within ABZR86_RS18220 at 62.525 kb on + strand, within ABZR86_RS18225 at 62.525 kb on + strand, within ABZR86_RS18225 at 62.525 kb on + strand, within ABZR86_RS18225 at 62.526 kb on - strand, within ABZR86_RS18225 at 62.526 kb on - strand, within ABZR86_RS18225 at 62.526 kb on - strand, within ABZR86_RS18225 at 62.638 kb on + strand at 62.638 kb on + strand at 62.651 kb on + strand at 62.651 kb on + strand at 62.651 kb on + strand at 62.652 kb on - strand at 62.655 kb on + strand at 62.655 kb on + strand at 62.656 kb on - strand at 62.656 kb on - strand at 62.656 kb on - strand at 62.656 kb on - strand at 62.656 kb on - strand at 62.656 kb on - strand at 62.661 kb on + strand at 62.661 kb on + strand at 62.661 kb on + strand at 62.661 kb on + strand at 62.662 kb on - strand at 62.818 kb on + strand at 62.955 kb on - strand, within ABZR86_RS18230 at 63.010 kb on + strand, within ABZR86_RS18230 at 63.010 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.105 kb on + strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.106 kb on - strand, within ABZR86_RS18230 at 63.111 kb on + strand, within ABZR86_RS18230 at 63.111 kb on + strand, within ABZR86_RS18230 at 63.112 kb on - strand, within ABZR86_RS18230 at 63.112 kb on - strand, within ABZR86_RS18230 at 63.112 kb on - strand, within ABZR86_RS18230 at 63.112 kb on - strand, within ABZR86_RS18230 at 63.112 kb on - strand, within ABZR86_RS18230 at 63.138 kb on + strand, within ABZR86_RS18230 at 63.138 kb on + strand, within ABZR86_RS18230 at 63.138 kb on + strand, within ABZR86_RS18230 at 63.138 kb on + strand, within ABZR86_RS18230 at 63.139 kb on - strand, within ABZR86_RS18230 at 63.139 kb on - strand, within ABZR86_RS18230 at 63.139 kb on - strand, within ABZR86_RS18230 at 63.139 kb on - strand, within ABZR86_RS18230 at 63.139 kb on - strand, within ABZR86_RS18230 at 63.229 kb on - strand, within ABZR86_RS18230 at 63.406 kb on - strand, within ABZR86_RS18230 at 63.417 kb on - strand, within ABZR86_RS18230 at 63.417 kb on - strand, within ABZR86_RS18230 at 63.435 kb on + strand, within ABZR86_RS18230 at 63.512 kb on + strand, within ABZR86_RS18230 at 63.548 kb on + strand, within ABZR86_RS18230 at 63.600 kb on + strand at 63.600 kb on + strand at 63.600 kb on + strand at 63.600 kb on + strand at 63.600 kb on + strand at 63.601 kb on - strand at 63.601 kb on - strand at 63.601 kb on - strand at 63.601 kb on - strand at 63.601 kb on - strand at 63.601 kb on - strand at 63.601 kb on - strand at 63.601 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction D-Cycloserine 0.032 mg/ml remove 61,459 + ABZR86_RS18215 0.39 +0.3 61,824 + -2.7 61,844 + +0.4 61,874 - +0.0 61,883 + +0.6 61,883 + +0.5 61,883 + -0.5 61,884 - -0.3 61,884 - -0.0 62,038 + ABZR86_RS18220 0.15 +1.1 62,039 - ABZR86_RS18220 0.15 +0.2 62,039 - ABZR86_RS18220 0.15 +0.0 62,185 + ABZR86_RS18220 0.49 +0.6 62,236 + ABZR86_RS18220 0.61 +1.7 62,236 + ABZR86_RS18220 0.61 -0.1 62,236 + ABZR86_RS18220 0.61 -0.1 62,236 + ABZR86_RS18220 0.61 +0.2 62,236 + ABZR86_RS18220 0.61 -0.0 62,236 + ABZR86_RS18220 0.61 -0.4 62,236 + ABZR86_RS18220 0.61 +0.3 62,236 + ABZR86_RS18220 0.61 +0.4 62,236 + ABZR86_RS18220 0.61 +1.0 62,236 + ABZR86_RS18220 0.61 -0.8 62,237 - ABZR86_RS18220 0.61 -0.5 62,237 - ABZR86_RS18220 0.61 -0.3 62,237 - ABZR86_RS18220 0.61 -0.1 62,237 - ABZR86_RS18220 0.61 +0.7 62,237 - ABZR86_RS18220 0.61 -1.7 62,242 + ABZR86_RS18220 0.62 +0.2 62,242 + ABZR86_RS18220 0.62 +0.4 62,242 + ABZR86_RS18220 0.62 -0.1 62,242 + ABZR86_RS18220 0.62 -0.1 62,242 + ABZR86_RS18220 0.62 -0.0 62,243 - ABZR86_RS18220 0.62 -0.1 62,243 - ABZR86_RS18220 0.62 -0.0 62,243 - ABZR86_RS18220 0.62 +0.2 62,245 + ABZR86_RS18220 0.63 +0.2 62,245 + ABZR86_RS18220 0.63 -0.4 62,245 + ABZR86_RS18220 0.63 -0.3 62,246 - ABZR86_RS18220 0.63 +0.2 62,246 - ABZR86_RS18220 0.63 -0.5 62,246 - ABZR86_RS18220 0.63 +0.3 62,525 + ABZR86_RS18225 0.61 -0.1 62,525 + ABZR86_RS18225 0.61 -0.1 62,525 + ABZR86_RS18225 0.61 +0.1 62,526 - ABZR86_RS18225 0.61 +0.6 62,526 - ABZR86_RS18225 0.61 -0.3 62,526 - ABZR86_RS18225 0.61 +0.7 62,638 + -0.0 62,638 + +0.7 62,651 + +0.4 62,651 + -0.0 62,651 + -0.6 62,652 - +1.0 62,655 + +0.3 62,655 + -0.8 62,656 - +0.3 62,656 - -0.7 62,656 - -0.7 62,656 - +0.2 62,656 - -0.2 62,656 - -0.1 62,661 + -0.2 62,661 + -0.5 62,661 + -0.3 62,661 + +0.2 62,662 - +0.4 62,818 + -0.5 62,955 - ABZR86_RS18230 0.19 +0.8 63,010 + ABZR86_RS18230 0.25 -0.2 63,010 + ABZR86_RS18230 0.25 -0.1 63,105 + ABZR86_RS18230 0.36 +0.1 63,105 + ABZR86_RS18230 0.36 -0.3 63,105 + ABZR86_RS18230 0.36 -0.5 63,105 + ABZR86_RS18230 0.36 -0.1 63,105 + ABZR86_RS18230 0.36 +0.5 63,105 + ABZR86_RS18230 0.36 +0.2 63,105 + ABZR86_RS18230 0.36 -0.1 63,105 + ABZR86_RS18230 0.36 +0.4 63,105 + ABZR86_RS18230 0.36 +0.7 63,106 - ABZR86_RS18230 0.36 -0.2 63,106 - ABZR86_RS18230 0.36 +0.5 63,106 - ABZR86_RS18230 0.36 +0.2 63,106 - ABZR86_RS18230 0.36 -0.1 63,106 - ABZR86_RS18230 0.36 -0.7 63,106 - ABZR86_RS18230 0.36 -0.7 63,106 - ABZR86_RS18230 0.36 -0.9 63,106 - ABZR86_RS18230 0.36 -0.6 63,111 + ABZR86_RS18230 0.37 -0.0 63,111 + ABZR86_RS18230 0.37 -0.5 63,112 - ABZR86_RS18230 0.37 +0.1 63,112 - ABZR86_RS18230 0.37 +0.6 63,112 - ABZR86_RS18230 0.37 +0.4 63,112 - ABZR86_RS18230 0.37 -0.6 63,112 - ABZR86_RS18230 0.37 +0.2 63,138 + ABZR86_RS18230 0.40 +0.2 63,138 + ABZR86_RS18230 0.40 +0.4 63,138 + ABZR86_RS18230 0.40 +1.1 63,138 + ABZR86_RS18230 0.40 -0.5 63,139 - ABZR86_RS18230 0.40 -0.9 63,139 - ABZR86_RS18230 0.40 -0.4 63,139 - ABZR86_RS18230 0.40 +2.4 63,139 - ABZR86_RS18230 0.40 -0.1 63,139 - ABZR86_RS18230 0.40 -0.2 63,229 - ABZR86_RS18230 0.50 +0.3 63,406 - ABZR86_RS18230 0.69 +1.2 63,417 - ABZR86_RS18230 0.71 +0.0 63,417 - ABZR86_RS18230 0.71 -0.0 63,435 + ABZR86_RS18230 0.73 -0.0 63,512 + ABZR86_RS18230 0.81 +0.1 63,548 + ABZR86_RS18230 0.85 +0.4 63,600 + +0.4 63,600 + -0.1 63,600 + -0.0 63,600 + -0.5 63,600 + +0.1 63,601 - +0.2 63,601 - -0.1 63,601 - +0.5 63,601 - -0.1 63,601 - +0.2 63,601 - +0.3 63,601 - -0.1 63,601 - +0.6
Or see this region's nucleotide sequence