Experiment: Ceftazidime 0.15 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf6N2E2_192 and Pf6N2E2_193 are separated by 377 nucleotides Pf6N2E2_193 and Pf6N2E2_194 overlap by 36 nucleotides Pf6N2E2_194 and Pf6N2E2_195 overlap by 4 nucleotides
Pf6N2E2_192 - hypothetical protein, at 244,676 to 246,115
_192
Pf6N2E2_193 - hypothetical protein, at 246,493 to 246,870
_193
Pf6N2E2_194 - Alcohol dehydrogenase (EC 1.1.1.1), at 246,835 to 247,569
_194
Pf6N2E2_195 - hypothetical protein, at 247,566 to 249,515
_195
Position (kb)
246
247
248 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 245.861 kb on + strand, within Pf6N2E2_192 at 246.091 kb on - strand at 246.091 kb on - strand at 246.173 kb on + strand at 246.173 kb on + strand at 246.174 kb on - strand at 246.174 kb on - strand at 246.249 kb on - strand at 246.253 kb on + strand at 246.254 kb on - strand at 246.254 kb on - strand at 246.254 kb on - strand at 246.254 kb on - strand at 246.286 kb on + strand at 246.286 kb on + strand at 246.304 kb on + strand at 246.304 kb on + strand at 246.304 kb on + strand at 246.305 kb on - strand at 246.305 kb on - strand at 246.305 kb on - strand at 246.305 kb on - strand at 246.305 kb on - strand at 246.353 kb on - strand at 246.462 kb on + strand at 246.465 kb on + strand at 246.465 kb on + strand at 246.465 kb on + strand at 246.498 kb on + strand at 246.498 kb on + strand at 246.500 kb on + strand at 246.511 kb on + strand at 246.511 kb on + strand at 246.512 kb on - strand at 246.517 kb on - strand at 246.539 kb on + strand, within Pf6N2E2_193 at 246.539 kb on + strand, within Pf6N2E2_193 at 246.539 kb on + strand, within Pf6N2E2_193 at 246.544 kb on + strand, within Pf6N2E2_193 at 246.544 kb on + strand, within Pf6N2E2_193 at 246.772 kb on - strand, within Pf6N2E2_193 at 246.889 kb on + strand at 246.889 kb on + strand at 246.889 kb on + strand at 246.890 kb on - strand at 247.116 kb on + strand, within Pf6N2E2_194 at 247.117 kb on - strand, within Pf6N2E2_194 at 247.205 kb on + strand, within Pf6N2E2_194 at 247.215 kb on + strand, within Pf6N2E2_194 at 247.216 kb on - strand, within Pf6N2E2_194 at 247.376 kb on - strand, within Pf6N2E2_194 at 247.376 kb on - strand, within Pf6N2E2_194 at 247.376 kb on - strand, within Pf6N2E2_194 at 247.376 kb on - strand, within Pf6N2E2_194 at 247.645 kb on + strand at 247.652 kb on - strand at 247.652 kb on - strand at 247.751 kb on + strand at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.861 kb on + strand, within Pf6N2E2_195 at 247.862 kb on - strand, within Pf6N2E2_195 at 247.862 kb on - strand, within Pf6N2E2_195 at 247.862 kb on - strand, within Pf6N2E2_195 at 247.862 kb on - strand, within Pf6N2E2_195 at 247.893 kb on + strand, within Pf6N2E2_195 at 247.893 kb on + strand, within Pf6N2E2_195 at 247.915 kb on + strand, within Pf6N2E2_195 at 247.916 kb on - strand, within Pf6N2E2_195 at 247.918 kb on + strand, within Pf6N2E2_195 at 247.918 kb on + strand, within Pf6N2E2_195 at 247.918 kb on + strand, within Pf6N2E2_195 at 247.918 kb on + strand, within Pf6N2E2_195 at 247.919 kb on - strand, within Pf6N2E2_195 at 247.921 kb on + strand, within Pf6N2E2_195 at 247.921 kb on + strand, within Pf6N2E2_195 at 247.921 kb on + strand, within Pf6N2E2_195 at 247.922 kb on - strand, within Pf6N2E2_195 at 247.922 kb on - strand, within Pf6N2E2_195 at 247.986 kb on - strand, within Pf6N2E2_195 at 248.008 kb on + strand, within Pf6N2E2_195 at 248.050 kb on + strand, within Pf6N2E2_195 at 248.106 kb on + strand, within Pf6N2E2_195 at 248.140 kb on + strand, within Pf6N2E2_195 at 248.227 kb on + strand, within Pf6N2E2_195 at 248.227 kb on + strand, within Pf6N2E2_195 at 248.228 kb on - strand, within Pf6N2E2_195 at 248.228 kb on - strand, within Pf6N2E2_195 at 248.268 kb on + strand, within Pf6N2E2_195 at 248.362 kb on + strand, within Pf6N2E2_195 at 248.362 kb on + strand, within Pf6N2E2_195 at 248.363 kb on - strand, within Pf6N2E2_195 at 248.363 kb on - strand, within Pf6N2E2_195 at 248.363 kb on - strand, within Pf6N2E2_195 at 248.449 kb on + strand, within Pf6N2E2_195 at 248.450 kb on - strand, within Pf6N2E2_195 at 248.524 kb on + strand, within Pf6N2E2_195
Per-strain Table
Position Strand Gene LocusTag Fraction Ceftazidime 0.15 mg/ml remove 245,861 + Pf6N2E2_192 0.82 +0.4 246,091 - +1.1 246,091 - +0.7 246,173 + -0.1 246,173 + -0.0 246,174 - +0.5 246,174 - -0.6 246,249 - +0.4 246,253 + -1.0 246,254 - +0.7 246,254 - +0.3 246,254 - +0.9 246,254 - +0.0 246,286 + -0.3 246,286 + -0.3 246,304 + +0.8 246,304 + +0.3 246,304 + +0.5 246,305 - +0.1 246,305 - +0.9 246,305 - +0.0 246,305 - -0.3 246,305 - -0.0 246,353 - +0.2 246,462 + +0.7 246,465 + +0.3 246,465 + -0.6 246,465 + -0.1 246,498 + +0.8 246,498 + +0.7 246,500 + +2.1 246,511 + +0.9 246,511 + +0.3 246,512 - -1.3 246,517 - -0.4 246,539 + Pf6N2E2_193 0.12 -0.7 246,539 + Pf6N2E2_193 0.12 -0.7 246,539 + Pf6N2E2_193 0.12 +0.7 246,544 + Pf6N2E2_193 0.13 -1.4 246,544 + Pf6N2E2_193 0.13 -0.8 246,772 - Pf6N2E2_193 0.74 -1.7 246,889 + -0.3 246,889 + -0.3 246,889 + +0.0 246,890 - -1.8 247,116 + Pf6N2E2_194 0.38 -0.9 247,117 - Pf6N2E2_194 0.38 -1.6 247,205 + Pf6N2E2_194 0.50 -0.6 247,215 + Pf6N2E2_194 0.52 +0.7 247,216 - Pf6N2E2_194 0.52 -0.5 247,376 - Pf6N2E2_194 0.74 -0.4 247,376 - Pf6N2E2_194 0.74 -1.2 247,376 - Pf6N2E2_194 0.74 -0.7 247,376 - Pf6N2E2_194 0.74 -0.2 247,645 + +0.4 247,652 - -0.0 247,652 - +0.4 247,751 + -0.1 247,861 + Pf6N2E2_195 0.15 +0.3 247,861 + Pf6N2E2_195 0.15 +0.1 247,861 + Pf6N2E2_195 0.15 +1.2 247,861 + Pf6N2E2_195 0.15 +0.1 247,861 + Pf6N2E2_195 0.15 -0.7 247,861 + Pf6N2E2_195 0.15 +0.7 247,861 + Pf6N2E2_195 0.15 -0.2 247,861 + Pf6N2E2_195 0.15 -0.1 247,861 + Pf6N2E2_195 0.15 +0.7 247,861 + Pf6N2E2_195 0.15 -0.0 247,862 - Pf6N2E2_195 0.15 -0.1 247,862 - Pf6N2E2_195 0.15 +1.4 247,862 - Pf6N2E2_195 0.15 +0.4 247,862 - Pf6N2E2_195 0.15 +0.6 247,893 + Pf6N2E2_195 0.17 +0.1 247,893 + Pf6N2E2_195 0.17 -0.7 247,915 + Pf6N2E2_195 0.18 +0.7 247,916 - Pf6N2E2_195 0.18 -0.7 247,918 + Pf6N2E2_195 0.18 -0.9 247,918 + Pf6N2E2_195 0.18 +0.6 247,918 + Pf6N2E2_195 0.18 +1.0 247,918 + Pf6N2E2_195 0.18 +0.7 247,919 - Pf6N2E2_195 0.18 +0.5 247,921 + Pf6N2E2_195 0.18 +0.1 247,921 + Pf6N2E2_195 0.18 -0.6 247,921 + Pf6N2E2_195 0.18 -0.3 247,922 - Pf6N2E2_195 0.18 -0.7 247,922 - Pf6N2E2_195 0.18 +0.4 247,986 - Pf6N2E2_195 0.22 +0.4 248,008 + Pf6N2E2_195 0.23 -0.3 248,050 + Pf6N2E2_195 0.25 -0.5 248,106 + Pf6N2E2_195 0.28 +0.5 248,140 + Pf6N2E2_195 0.29 +1.5 248,227 + Pf6N2E2_195 0.34 -0.1 248,227 + Pf6N2E2_195 0.34 -0.7 248,228 - Pf6N2E2_195 0.34 +0.9 248,228 - Pf6N2E2_195 0.34 +0.4 248,268 + Pf6N2E2_195 0.36 -0.1 248,362 + Pf6N2E2_195 0.41 +1.7 248,362 + Pf6N2E2_195 0.41 +1.3 248,363 - Pf6N2E2_195 0.41 -0.8 248,363 - Pf6N2E2_195 0.41 +0.6 248,363 - Pf6N2E2_195 0.41 +0.2 248,449 + Pf6N2E2_195 0.45 +0.0 248,450 - Pf6N2E2_195 0.45 -0.5 248,524 + Pf6N2E2_195 0.49 +0.5
Or see this region's nucleotide sequence