Experiment: Doxycycline hyclate 0.0001 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf6N2E2_4819 and Pf6N2E2_4820 are separated by 78 nucleotides Pf6N2E2_4820 and Pf6N2E2_4821 overlap by 4 nucleotides Pf6N2E2_4821 and Pf6N2E2_4822 are separated by 70 nucleotides
Pf6N2E2_4819 - Alcohol dehydrogenase (EC 1.1.1.1), at 5,572,498 to 5,573,646
_4819
Pf6N2E2_4820 - Ribulose-phosphate 3-epimerase (EC 5.1.3.1), at 5,573,725 to 5,574,399
_4820
Pf6N2E2_4821 - Phosphoglycolate phosphatase (EC 3.1.3.18), at 5,574,396 to 5,575,214
_4821
Pf6N2E2_4822 - Anthranilate synthase, aminase component (EC 4.1.3.27), at 5,575,285 to 5,576,766
_4822
Position (kb)
5573
5574
5575 Strain fitness (log2 ratio)
-2
-1
0
1
2
3
4
5 at 5572.819 kb on + strand, within Pf6N2E2_4819 at 5572.819 kb on + strand, within Pf6N2E2_4819 at 5572.820 kb on - strand, within Pf6N2E2_4819 at 5572.820 kb on - strand, within Pf6N2E2_4819 at 5572.820 kb on - strand, within Pf6N2E2_4819 at 5572.820 kb on - strand, within Pf6N2E2_4819 at 5572.820 kb on - strand, within Pf6N2E2_4819 at 5572.820 kb on - strand, within Pf6N2E2_4819 at 5572.848 kb on + strand, within Pf6N2E2_4819 at 5572.848 kb on + strand, within Pf6N2E2_4819 at 5572.848 kb on + strand, within Pf6N2E2_4819 at 5572.849 kb on - strand, within Pf6N2E2_4819 at 5572.990 kb on + strand, within Pf6N2E2_4819 at 5572.990 kb on + strand, within Pf6N2E2_4819 at 5572.990 kb on + strand, within Pf6N2E2_4819 at 5572.990 kb on + strand, within Pf6N2E2_4819 at 5572.990 kb on + strand, within Pf6N2E2_4819 at 5572.990 kb on + strand, within Pf6N2E2_4819 at 5572.991 kb on - strand, within Pf6N2E2_4819 at 5572.991 kb on - strand, within Pf6N2E2_4819 at 5572.991 kb on - strand, within Pf6N2E2_4819 at 5572.991 kb on - strand, within Pf6N2E2_4819 at 5573.098 kb on + strand, within Pf6N2E2_4819 at 5573.098 kb on + strand, within Pf6N2E2_4819 at 5573.099 kb on - strand, within Pf6N2E2_4819 at 5573.182 kb on + strand, within Pf6N2E2_4819 at 5573.182 kb on + strand, within Pf6N2E2_4819 at 5573.182 kb on + strand, within Pf6N2E2_4819 at 5573.183 kb on - strand, within Pf6N2E2_4819 at 5573.183 kb on - strand, within Pf6N2E2_4819 at 5573.183 kb on - strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.337 kb on + strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.338 kb on - strand, within Pf6N2E2_4819 at 5573.350 kb on + strand, within Pf6N2E2_4819 at 5573.350 kb on + strand, within Pf6N2E2_4819 at 5573.351 kb on - strand, within Pf6N2E2_4819 at 5573.351 kb on - strand, within Pf6N2E2_4819 at 5573.475 kb on + strand, within Pf6N2E2_4819 at 5573.475 kb on + strand, within Pf6N2E2_4819 at 5573.476 kb on - strand, within Pf6N2E2_4819 at 5573.476 kb on - strand, within Pf6N2E2_4819 at 5573.476 kb on - strand, within Pf6N2E2_4819 at 5573.476 kb on - strand, within Pf6N2E2_4819 at 5573.476 kb on - strand, within Pf6N2E2_4819 at 5573.499 kb on - strand, within Pf6N2E2_4819 at 5573.570 kb on + strand at 5573.630 kb on - strand at 5573.641 kb on + strand at 5573.642 kb on - strand at 5573.681 kb on + strand at 5573.681 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.683 kb on + strand at 5573.684 kb on - strand at 5573.684 kb on - strand at 5573.684 kb on - strand at 5573.684 kb on - strand at 5573.684 kb on - strand at 5574.550 kb on + strand, within Pf6N2E2_4821 at 5574.764 kb on + strand, within Pf6N2E2_4821 at 5574.764 kb on + strand, within Pf6N2E2_4821 at 5574.765 kb on - strand, within Pf6N2E2_4821 at 5574.765 kb on - strand, within Pf6N2E2_4821 at 5574.848 kb on + strand, within Pf6N2E2_4821 at 5574.999 kb on + strand, within Pf6N2E2_4821 at 5575.006 kb on - strand, within Pf6N2E2_4821 at 5575.069 kb on + strand, within Pf6N2E2_4821 at 5575.069 kb on + strand, within Pf6N2E2_4821 at 5575.069 kb on + strand, within Pf6N2E2_4821 at 5575.070 kb on - strand, within Pf6N2E2_4821 at 5575.102 kb on + strand, within Pf6N2E2_4821 at 5575.102 kb on + strand, within Pf6N2E2_4821 at 5575.102 kb on + strand, within Pf6N2E2_4821 at 5575.103 kb on - strand, within Pf6N2E2_4821 at 5575.103 kb on - strand, within Pf6N2E2_4821 at 5575.103 kb on - strand, within Pf6N2E2_4821 at 5575.103 kb on - strand, within Pf6N2E2_4821 at 5575.103 kb on - strand, within Pf6N2E2_4821 at 5575.248 kb on + strand at 5575.248 kb on + strand at 5575.249 kb on - strand at 5575.249 kb on - strand at 5575.324 kb on + strand at 5575.325 kb on - strand at 5575.385 kb on - strand at 5575.385 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Doxycycline hyclate 0.0001 mg/ml remove 5,572,819 + Pf6N2E2_4819 0.28 -1.8 5,572,819 + Pf6N2E2_4819 0.28 -1.2 5,572,820 - Pf6N2E2_4819 0.28 +0.6 5,572,820 - Pf6N2E2_4819 0.28 +0.2 5,572,820 - Pf6N2E2_4819 0.28 +0.9 5,572,820 - Pf6N2E2_4819 0.28 -0.0 5,572,820 - Pf6N2E2_4819 0.28 +0.6 5,572,820 - Pf6N2E2_4819 0.28 +0.4 5,572,848 + Pf6N2E2_4819 0.30 -0.5 5,572,848 + Pf6N2E2_4819 0.30 -1.6 5,572,848 + Pf6N2E2_4819 0.30 -1.2 5,572,849 - Pf6N2E2_4819 0.31 -0.9 5,572,990 + Pf6N2E2_4819 0.43 +1.7 5,572,990 + Pf6N2E2_4819 0.43 +0.0 5,572,990 + Pf6N2E2_4819 0.43 +0.1 5,572,990 + Pf6N2E2_4819 0.43 +0.0 5,572,990 + Pf6N2E2_4819 0.43 +0.4 5,572,990 + Pf6N2E2_4819 0.43 +1.0 5,572,991 - Pf6N2E2_4819 0.43 +1.0 5,572,991 - Pf6N2E2_4819 0.43 +0.6 5,572,991 - Pf6N2E2_4819 0.43 -0.5 5,572,991 - Pf6N2E2_4819 0.43 +0.0 5,573,098 + Pf6N2E2_4819 0.52 -1.8 5,573,098 + Pf6N2E2_4819 0.52 +1.8 5,573,099 - Pf6N2E2_4819 0.52 +1.1 5,573,182 + Pf6N2E2_4819 0.60 +0.7 5,573,182 + Pf6N2E2_4819 0.60 +0.4 5,573,182 + Pf6N2E2_4819 0.60 -0.1 5,573,183 - Pf6N2E2_4819 0.60 -0.0 5,573,183 - Pf6N2E2_4819 0.60 +0.1 5,573,183 - Pf6N2E2_4819 0.60 +0.6 5,573,337 + Pf6N2E2_4819 0.73 +0.6 5,573,337 + Pf6N2E2_4819 0.73 -0.0 5,573,337 + Pf6N2E2_4819 0.73 +0.8 5,573,337 + Pf6N2E2_4819 0.73 -0.2 5,573,337 + Pf6N2E2_4819 0.73 +0.4 5,573,337 + Pf6N2E2_4819 0.73 +0.2 5,573,337 + Pf6N2E2_4819 0.73 +1.3 5,573,337 + Pf6N2E2_4819 0.73 +1.2 5,573,337 + Pf6N2E2_4819 0.73 -0.2 5,573,338 - Pf6N2E2_4819 0.73 +0.2 5,573,338 - Pf6N2E2_4819 0.73 -0.3 5,573,338 - Pf6N2E2_4819 0.73 -1.4 5,573,338 - Pf6N2E2_4819 0.73 -0.0 5,573,338 - Pf6N2E2_4819 0.73 -1.2 5,573,338 - Pf6N2E2_4819 0.73 +0.9 5,573,338 - Pf6N2E2_4819 0.73 -0.5 5,573,338 - Pf6N2E2_4819 0.73 +0.4 5,573,338 - Pf6N2E2_4819 0.73 +0.4 5,573,350 + Pf6N2E2_4819 0.74 -1.4 5,573,350 + Pf6N2E2_4819 0.74 +0.2 5,573,351 - Pf6N2E2_4819 0.74 +5.4 5,573,351 - Pf6N2E2_4819 0.74 -0.1 5,573,475 + Pf6N2E2_4819 0.85 +0.3 5,573,475 + Pf6N2E2_4819 0.85 +0.6 5,573,476 - Pf6N2E2_4819 0.85 -1.2 5,573,476 - Pf6N2E2_4819 0.85 -0.0 5,573,476 - Pf6N2E2_4819 0.85 +0.5 5,573,476 - Pf6N2E2_4819 0.85 +0.7 5,573,476 - Pf6N2E2_4819 0.85 -1.1 5,573,499 - Pf6N2E2_4819 0.87 -0.9 5,573,570 + -0.7 5,573,630 - +0.5 5,573,641 + +0.6 5,573,642 - +1.1 5,573,681 + -0.0 5,573,681 + +0.0 5,573,683 + -0.4 5,573,683 + +1.2 5,573,683 + -1.1 5,573,683 + -0.7 5,573,683 + +0.2 5,573,683 + +1.0 5,573,683 + -0.0 5,573,683 + +2.0 5,573,683 + +0.1 5,573,684 - +2.3 5,573,684 - +3.1 5,573,684 - +1.5 5,573,684 - +1.5 5,573,684 - +1.0 5,574,550 + Pf6N2E2_4821 0.19 -1.6 5,574,764 + Pf6N2E2_4821 0.45 +0.6 5,574,764 + Pf6N2E2_4821 0.45 -0.5 5,574,765 - Pf6N2E2_4821 0.45 -1.7 5,574,765 - Pf6N2E2_4821 0.45 -0.8 5,574,848 + Pf6N2E2_4821 0.55 -0.4 5,574,999 + Pf6N2E2_4821 0.74 -1.2 5,575,006 - Pf6N2E2_4821 0.74 -0.8 5,575,069 + Pf6N2E2_4821 0.82 -0.1 5,575,069 + Pf6N2E2_4821 0.82 +0.1 5,575,069 + Pf6N2E2_4821 0.82 -2.3 5,575,070 - Pf6N2E2_4821 0.82 -1.7 5,575,102 + Pf6N2E2_4821 0.86 -1.6 5,575,102 + Pf6N2E2_4821 0.86 +0.7 5,575,102 + Pf6N2E2_4821 0.86 -0.6 5,575,103 - Pf6N2E2_4821 0.86 +0.2 5,575,103 - Pf6N2E2_4821 0.86 -1.6 5,575,103 - Pf6N2E2_4821 0.86 -2.2 5,575,103 - Pf6N2E2_4821 0.86 -1.0 5,575,103 - Pf6N2E2_4821 0.86 -0.8 5,575,248 + +0.5 5,575,248 + -0.6 5,575,249 - -0.4 5,575,249 - +0.8 5,575,324 + +0.8 5,575,325 - +0.5 5,575,385 - +0.2 5,575,385 - +0.3
Or see this region's nucleotide sequence