Experiment: Vancomycin 0.24 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf6N2E2_3408 and Pf6N2E2_3409 are separated by 30 nucleotides Pf6N2E2_3409 and Pf6N2E2_3410 are separated by 24 nucleotides Pf6N2E2_3410 and Pf6N2E2_3411 are separated by 28 nucleotides Pf6N2E2_3411 and Pf6N2E2_3412 are separated by 5 nucleotides Pf6N2E2_3412 and Pf6N2E2_3413 are separated by 22 nucleotides
Pf6N2E2_3408 - Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain, at 3,952,189 to 3,953,277
_3408
Pf6N2E2_3409 - Hypothetical transcriptional regulator YqhC, at 3,953,308 to 3,954,246
_3409
Pf6N2E2_3410 - Short-chain dehydrogenase/reductase SDR, at 3,954,271 to 3,955,104
_3410
Pf6N2E2_3411 - hypothetical protein, at 3,955,133 to 3,955,258
_3411
Pf6N2E2_3412 - FIG006045: Sigma factor, ECF subfamily, at 3,955,264 to 3,955,818
_3412
Pf6N2E2_3413 - Fe2+-dicitrate sensor, membrane component, at 3,955,841 to 3,956,788
_3413
Position (kb)
3954
3955
3956 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 3953.276 kb on - strand at 3953.324 kb on + strand at 3953.324 kb on + strand at 3953.324 kb on + strand at 3953.325 kb on - strand at 3953.325 kb on - strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.357 kb on + strand at 3953.358 kb on - strand at 3953.358 kb on - strand at 3953.358 kb on - strand at 3953.358 kb on - strand at 3953.358 kb on - strand at 3953.358 kb on - strand at 3953.358 kb on - strand at 3953.445 kb on - strand, within Pf6N2E2_3409 at 3953.531 kb on + strand, within Pf6N2E2_3409 at 3953.636 kb on + strand, within Pf6N2E2_3409 at 3953.636 kb on + strand, within Pf6N2E2_3409 at 3953.637 kb on - strand, within Pf6N2E2_3409 at 3953.744 kb on + strand, within Pf6N2E2_3409 at 3953.744 kb on + strand, within Pf6N2E2_3409 at 3953.744 kb on + strand, within Pf6N2E2_3409 at 3953.745 kb on - strand, within Pf6N2E2_3409 at 3953.745 kb on - strand, within Pf6N2E2_3409 at 3953.828 kb on + strand, within Pf6N2E2_3409 at 3953.855 kb on + strand, within Pf6N2E2_3409 at 3953.855 kb on + strand, within Pf6N2E2_3409 at 3953.855 kb on + strand, within Pf6N2E2_3409 at 3953.855 kb on + strand, within Pf6N2E2_3409 at 3953.855 kb on + strand, within Pf6N2E2_3409 at 3953.855 kb on + strand, within Pf6N2E2_3409 at 3953.856 kb on - strand, within Pf6N2E2_3409 at 3953.856 kb on - strand, within Pf6N2E2_3409 at 3953.856 kb on - strand, within Pf6N2E2_3409 at 3953.856 kb on - strand, within Pf6N2E2_3409 at 3953.856 kb on - strand, within Pf6N2E2_3409 at 3953.856 kb on - strand, within Pf6N2E2_3409 at 3953.856 kb on - strand, within Pf6N2E2_3409 at 3953.908 kb on + strand, within Pf6N2E2_3409 at 3953.909 kb on - strand, within Pf6N2E2_3409 at 3953.909 kb on - strand, within Pf6N2E2_3409 at 3953.909 kb on - strand, within Pf6N2E2_3409 at 3953.943 kb on + strand, within Pf6N2E2_3409 at 3953.943 kb on + strand, within Pf6N2E2_3409 at 3953.943 kb on + strand, within Pf6N2E2_3409 at 3953.943 kb on + strand, within Pf6N2E2_3409 at 3953.944 kb on - strand, within Pf6N2E2_3409 at 3953.944 kb on - strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.945 kb on + strand, within Pf6N2E2_3409 at 3953.946 kb on - strand, within Pf6N2E2_3409 at 3953.946 kb on - strand, within Pf6N2E2_3409 at 3953.946 kb on - strand, within Pf6N2E2_3409 at 3953.946 kb on - strand, within Pf6N2E2_3409 at 3953.946 kb on - strand, within Pf6N2E2_3409 at 3953.946 kb on - strand, within Pf6N2E2_3409 at 3953.946 kb on - strand, within Pf6N2E2_3409 at 3954.020 kb on + strand, within Pf6N2E2_3409 at 3954.036 kb on - strand, within Pf6N2E2_3409 at 3954.036 kb on - strand, within Pf6N2E2_3409 at 3954.036 kb on - strand, within Pf6N2E2_3409 at 3954.041 kb on + strand, within Pf6N2E2_3409 at 3954.041 kb on + strand, within Pf6N2E2_3409 at 3954.042 kb on - strand, within Pf6N2E2_3409 at 3954.042 kb on - strand, within Pf6N2E2_3409 at 3954.104 kb on + strand, within Pf6N2E2_3409 at 3954.104 kb on + strand, within Pf6N2E2_3409 at 3954.104 kb on + strand, within Pf6N2E2_3409 at 3954.105 kb on - strand, within Pf6N2E2_3409 at 3954.105 kb on - strand, within Pf6N2E2_3409 at 3954.105 kb on - strand, within Pf6N2E2_3409 at 3954.151 kb on + strand, within Pf6N2E2_3409 at 3954.151 kb on + strand, within Pf6N2E2_3409 at 3954.151 kb on + strand, within Pf6N2E2_3409 at 3954.152 kb on - strand, within Pf6N2E2_3409 at 3954.152 kb on - strand, within Pf6N2E2_3409 at 3954.152 kb on - strand, within Pf6N2E2_3409 at 3954.152 kb on - strand, within Pf6N2E2_3409 at 3954.176 kb on + strand at 3954.176 kb on + strand at 3954.176 kb on + strand at 3954.177 kb on - strand at 3954.337 kb on - strand at 3954.500 kb on + strand, within Pf6N2E2_3410 at 3954.657 kb on - strand, within Pf6N2E2_3410 at 3954.657 kb on - strand, within Pf6N2E2_3410 at 3954.657 kb on - strand, within Pf6N2E2_3410 at 3954.657 kb on - strand, within Pf6N2E2_3410 at 3954.659 kb on + strand, within Pf6N2E2_3410 at 3954.659 kb on + strand, within Pf6N2E2_3410 at 3954.660 kb on - strand, within Pf6N2E2_3410 at 3954.660 kb on - strand, within Pf6N2E2_3410 at 3954.711 kb on + strand, within Pf6N2E2_3410 at 3954.711 kb on + strand, within Pf6N2E2_3410 at 3955.121 kb on + strand at 3955.121 kb on + strand at 3955.122 kb on - strand at 3955.138 kb on - strand at 3955.160 kb on + strand, within Pf6N2E2_3411 at 3955.161 kb on - strand, within Pf6N2E2_3411 at 3955.161 kb on - strand, within Pf6N2E2_3411 at 3955.161 kb on - strand, within Pf6N2E2_3411 at 3955.161 kb on - strand, within Pf6N2E2_3411 at 3955.187 kb on + strand, within Pf6N2E2_3411 at 3955.187 kb on + strand, within Pf6N2E2_3411 at 3955.188 kb on - strand, within Pf6N2E2_3411 at 3955.193 kb on + strand, within Pf6N2E2_3411 at 3955.193 kb on + strand, within Pf6N2E2_3411 at 3955.193 kb on + strand, within Pf6N2E2_3411 at 3955.193 kb on + strand, within Pf6N2E2_3411 at 3955.194 kb on - strand, within Pf6N2E2_3411 at 3955.490 kb on - strand, within Pf6N2E2_3412 at 3955.555 kb on + strand, within Pf6N2E2_3412 at 3955.555 kb on + strand, within Pf6N2E2_3412 at 3955.556 kb on - strand, within Pf6N2E2_3412 at 3955.640 kb on + strand, within Pf6N2E2_3412 at 3955.640 kb on + strand, within Pf6N2E2_3412 at 3955.641 kb on - strand, within Pf6N2E2_3412 at 3955.689 kb on - strand, within Pf6N2E2_3412 at 3955.724 kb on + strand, within Pf6N2E2_3412 at 3955.725 kb on - strand, within Pf6N2E2_3412 at 3955.752 kb on + strand, within Pf6N2E2_3412 at 3955.752 kb on + strand, within Pf6N2E2_3412 at 3955.752 kb on + strand, within Pf6N2E2_3412 at 3955.753 kb on - strand, within Pf6N2E2_3412 at 3955.792 kb on + strand at 3955.793 kb on - strand at 3955.817 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Vancomycin 0.24 mg/ml remove 3,953,276 - -0.1 3,953,324 + +0.4 3,953,324 + -0.8 3,953,324 + +0.1 3,953,325 - +0.5 3,953,325 - +0.3 3,953,357 + +1.4 3,953,357 + +0.6 3,953,357 + -0.4 3,953,357 + -0.6 3,953,357 + +0.3 3,953,357 + -1.4 3,953,357 + -1.1 3,953,357 + +0.3 3,953,357 + -0.1 3,953,357 + +0.3 3,953,358 - -0.6 3,953,358 - +1.1 3,953,358 - +2.1 3,953,358 - -0.6 3,953,358 - +1.2 3,953,358 - +0.6 3,953,358 - -1.7 3,953,445 - Pf6N2E2_3409 0.15 -0.2 3,953,531 + Pf6N2E2_3409 0.24 -0.3 3,953,636 + Pf6N2E2_3409 0.35 +0.6 3,953,636 + Pf6N2E2_3409 0.35 +0.3 3,953,637 - Pf6N2E2_3409 0.35 -0.3 3,953,744 + Pf6N2E2_3409 0.46 +1.0 3,953,744 + Pf6N2E2_3409 0.46 +1.5 3,953,744 + Pf6N2E2_3409 0.46 +1.0 3,953,745 - Pf6N2E2_3409 0.47 +0.2 3,953,745 - Pf6N2E2_3409 0.47 +0.5 3,953,828 + Pf6N2E2_3409 0.55 +1.2 3,953,855 + Pf6N2E2_3409 0.58 -0.1 3,953,855 + Pf6N2E2_3409 0.58 +0.6 3,953,855 + Pf6N2E2_3409 0.58 -1.1 3,953,855 + Pf6N2E2_3409 0.58 +1.3 3,953,855 + Pf6N2E2_3409 0.58 -0.3 3,953,855 + Pf6N2E2_3409 0.58 -0.2 3,953,856 - Pf6N2E2_3409 0.58 -0.9 3,953,856 - Pf6N2E2_3409 0.58 -2.0 3,953,856 - Pf6N2E2_3409 0.58 +0.1 3,953,856 - Pf6N2E2_3409 0.58 -1.9 3,953,856 - Pf6N2E2_3409 0.58 +0.8 3,953,856 - Pf6N2E2_3409 0.58 +0.1 3,953,856 - Pf6N2E2_3409 0.58 +0.0 3,953,908 + Pf6N2E2_3409 0.64 +0.1 3,953,909 - Pf6N2E2_3409 0.64 +1.0 3,953,909 - Pf6N2E2_3409 0.64 +0.5 3,953,909 - Pf6N2E2_3409 0.64 +1.9 3,953,943 + Pf6N2E2_3409 0.68 +0.3 3,953,943 + Pf6N2E2_3409 0.68 +0.9 3,953,943 + Pf6N2E2_3409 0.68 -1.3 3,953,943 + Pf6N2E2_3409 0.68 -0.5 3,953,944 - Pf6N2E2_3409 0.68 -0.7 3,953,944 - Pf6N2E2_3409 0.68 -0.2 3,953,945 + Pf6N2E2_3409 0.68 +0.8 3,953,945 + Pf6N2E2_3409 0.68 -1.5 3,953,945 + Pf6N2E2_3409 0.68 -0.9 3,953,945 + Pf6N2E2_3409 0.68 +0.7 3,953,945 + Pf6N2E2_3409 0.68 -0.1 3,953,945 + Pf6N2E2_3409 0.68 +1.4 3,953,945 + Pf6N2E2_3409 0.68 -1.5 3,953,945 + Pf6N2E2_3409 0.68 +0.5 3,953,945 + Pf6N2E2_3409 0.68 +0.6 3,953,945 + Pf6N2E2_3409 0.68 -0.1 3,953,945 + Pf6N2E2_3409 0.68 -0.9 3,953,946 - Pf6N2E2_3409 0.68 -0.3 3,953,946 - Pf6N2E2_3409 0.68 -0.5 3,953,946 - Pf6N2E2_3409 0.68 +0.5 3,953,946 - Pf6N2E2_3409 0.68 -0.5 3,953,946 - Pf6N2E2_3409 0.68 +0.7 3,953,946 - Pf6N2E2_3409 0.68 +1.5 3,953,946 - Pf6N2E2_3409 0.68 +0.5 3,954,020 + Pf6N2E2_3409 0.76 -0.8 3,954,036 - Pf6N2E2_3409 0.78 -0.2 3,954,036 - Pf6N2E2_3409 0.78 -1.4 3,954,036 - Pf6N2E2_3409 0.78 -0.9 3,954,041 + Pf6N2E2_3409 0.78 +0.2 3,954,041 + Pf6N2E2_3409 0.78 +0.4 3,954,042 - Pf6N2E2_3409 0.78 +0.4 3,954,042 - Pf6N2E2_3409 0.78 +0.7 3,954,104 + Pf6N2E2_3409 0.85 +0.2 3,954,104 + Pf6N2E2_3409 0.85 -1.8 3,954,104 + Pf6N2E2_3409 0.85 -0.4 3,954,105 - Pf6N2E2_3409 0.85 +0.6 3,954,105 - Pf6N2E2_3409 0.85 +0.3 3,954,105 - Pf6N2E2_3409 0.85 +0.4 3,954,151 + Pf6N2E2_3409 0.90 +2.0 3,954,151 + Pf6N2E2_3409 0.90 -1.2 3,954,151 + Pf6N2E2_3409 0.90 +0.1 3,954,152 - Pf6N2E2_3409 0.90 -0.7 3,954,152 - Pf6N2E2_3409 0.90 -0.1 3,954,152 - Pf6N2E2_3409 0.90 -0.3 3,954,152 - Pf6N2E2_3409 0.90 +0.9 3,954,176 + +0.7 3,954,176 + -0.3 3,954,176 + -1.4 3,954,177 - +2.6 3,954,337 - +0.1 3,954,500 + Pf6N2E2_3410 0.27 -0.3 3,954,657 - Pf6N2E2_3410 0.46 -1.4 3,954,657 - Pf6N2E2_3410 0.46 -0.5 3,954,657 - Pf6N2E2_3410 0.46 +0.5 3,954,657 - Pf6N2E2_3410 0.46 -0.2 3,954,659 + Pf6N2E2_3410 0.47 -1.0 3,954,659 + Pf6N2E2_3410 0.47 -1.6 3,954,660 - Pf6N2E2_3410 0.47 -0.2 3,954,660 - Pf6N2E2_3410 0.47 +0.6 3,954,711 + Pf6N2E2_3410 0.53 -0.5 3,954,711 + Pf6N2E2_3410 0.53 -0.9 3,955,121 + -0.5 3,955,121 + +0.3 3,955,122 - +0.1 3,955,138 - +0.5 3,955,160 + Pf6N2E2_3411 0.21 -0.0 3,955,161 - Pf6N2E2_3411 0.22 +0.0 3,955,161 - Pf6N2E2_3411 0.22 -0.5 3,955,161 - Pf6N2E2_3411 0.22 +0.0 3,955,161 - Pf6N2E2_3411 0.22 -0.3 3,955,187 + Pf6N2E2_3411 0.43 -0.3 3,955,187 + Pf6N2E2_3411 0.43 +0.2 3,955,188 - Pf6N2E2_3411 0.44 +0.1 3,955,193 + Pf6N2E2_3411 0.48 -0.1 3,955,193 + Pf6N2E2_3411 0.48 +0.4 3,955,193 + Pf6N2E2_3411 0.48 -0.1 3,955,193 + Pf6N2E2_3411 0.48 -1.3 3,955,194 - Pf6N2E2_3411 0.48 -0.1 3,955,490 - Pf6N2E2_3412 0.41 +0.7 3,955,555 + Pf6N2E2_3412 0.52 -0.1 3,955,555 + Pf6N2E2_3412 0.52 +0.8 3,955,556 - Pf6N2E2_3412 0.53 -0.1 3,955,640 + Pf6N2E2_3412 0.68 +0.1 3,955,640 + Pf6N2E2_3412 0.68 +0.2 3,955,641 - Pf6N2E2_3412 0.68 -2.5 3,955,689 - Pf6N2E2_3412 0.77 -1.4 3,955,724 + Pf6N2E2_3412 0.83 -1.9 3,955,725 - Pf6N2E2_3412 0.83 +1.0 3,955,752 + Pf6N2E2_3412 0.88 -0.2 3,955,752 + Pf6N2E2_3412 0.88 +0.8 3,955,752 + Pf6N2E2_3412 0.88 +0.5 3,955,753 - Pf6N2E2_3412 0.88 -2.0 3,955,792 + +0.5 3,955,793 - -1.4 3,955,817 - -0.3
Or see this region's nucleotide sequence