Experiment: PYE with Cisplatin 0.005 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt CCNA_02967 and CCNA_03902 are separated by 58 nucleotides CCNA_03902 and CCNA_03883 overlap by 4 nucleotides CCNA_03883 and CCNA_02969 are separated by 68 nucleotides CCNA_02969 and CCNA_02970 are separated by 42 nucleotides CCNA_02970 and CCNA_02971 are separated by 1 nucleotides
CCNA_02967: CCNA_02967 - PAS-family sensor histidine kinase, at 3,122,780 to 3,125,179
_02967
CCNA_03902: CCNA_03902 - hypothetical protein, at 3,125,238 to 3,125,573
_03902
CCNA_03883: CCNA_03883 - hypothetical protein, at 3,125,570 to 3,125,986
_03883
CCNA_02969: CCNA_02969 - TetR-family transcriptional regulator, at 3,126,055 to 3,126,609
_02969
CCNA_02970: CCNA_02970 - putative thiol-disulfide oxidoreductase, at 3,126,652 to 3,127,023
_02970
CCNA_02971: CCNA_02971 - membrane permease, at 3,127,025 to 3,128,053
_02971
Position (kb)
3126
3127 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 3125.067 kb on - strand at 3125.074 kb on - strand at 3125.081 kb on + strand at 3125.081 kb on + strand at 3125.083 kb on - strand at 3125.089 kb on - strand at 3125.150 kb on - strand at 3125.153 kb on + strand at 3125.171 kb on - strand at 3125.195 kb on - strand at 3125.244 kb on - strand at 3125.326 kb on + strand, within CCNA_03902 at 3125.328 kb on + strand, within CCNA_03902 at 3125.334 kb on - strand, within CCNA_03902 at 3125.334 kb on - strand, within CCNA_03902 at 3125.351 kb on + strand, within CCNA_03902 at 3125.351 kb on + strand, within CCNA_03902 at 3125.351 kb on + strand, within CCNA_03902 at 3125.351 kb on + strand, within CCNA_03902 at 3125.352 kb on + strand at 3125.359 kb on - strand, within CCNA_03902 at 3125.397 kb on + strand, within CCNA_03902 at 3125.408 kb on + strand, within CCNA_03902 at 3125.433 kb on + strand, within CCNA_03902 at 3125.448 kb on + strand, within CCNA_03902 at 3125.451 kb on - strand, within CCNA_03902 at 3125.451 kb on - strand, within CCNA_03902 at 3125.521 kb on - strand, within CCNA_03902 at 3125.523 kb on + strand, within CCNA_03902 at 3125.524 kb on - strand, within CCNA_03902 at 3125.539 kb on + strand, within CCNA_03902 at 3125.544 kb on + strand at 3125.558 kb on + strand at 3125.607 kb on + strand at 3125.648 kb on + strand, within CCNA_03883 at 3125.668 kb on - strand, within CCNA_03883 at 3125.668 kb on - strand, within CCNA_03883 at 3125.760 kb on + strand, within CCNA_03883 at 3125.775 kb on + strand, within CCNA_03883 at 3125.823 kb on - strand, within CCNA_03883 at 3125.845 kb on + strand, within CCNA_03883 at 3125.848 kb on - strand, within CCNA_03883 at 3125.853 kb on - strand, within CCNA_03883 at 3125.853 kb on - strand, within CCNA_03883 at 3125.880 kb on + strand, within CCNA_03883 at 3125.893 kb on + strand, within CCNA_03883 at 3125.898 kb on + strand, within CCNA_03883 at 3125.906 kb on - strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.939 kb on + strand, within CCNA_03883 at 3125.947 kb on - strand at 3125.947 kb on - strand at 3125.947 kb on - strand at 3125.947 kb on - strand at 3125.947 kb on - strand at 3126.052 kb on + strand at 3126.100 kb on + strand at 3126.121 kb on + strand, within CCNA_02969 at 3126.129 kb on - strand, within CCNA_02969 at 3126.186 kb on + strand, within CCNA_02969 at 3126.204 kb on + strand, within CCNA_02969 at 3126.211 kb on + strand, within CCNA_02969 at 3126.211 kb on + strand, within CCNA_02969 at 3126.216 kb on + strand, within CCNA_02969 at 3126.226 kb on + strand, within CCNA_02969 at 3126.258 kb on + strand, within CCNA_02969 at 3126.301 kb on + strand, within CCNA_02969 at 3126.309 kb on + strand, within CCNA_02969 at 3126.323 kb on - strand, within CCNA_02969 at 3126.397 kb on + strand, within CCNA_02969 at 3126.430 kb on + strand, within CCNA_02969 at 3126.449 kb on + strand, within CCNA_02969 at 3126.502 kb on + strand, within CCNA_02969 at 3126.509 kb on + strand, within CCNA_02969 at 3126.509 kb on + strand, within CCNA_02969 at 3126.509 kb on + strand, within CCNA_02969 at 3126.509 kb on + strand, within CCNA_02969 at 3126.527 kb on + strand, within CCNA_02969 at 3126.536 kb on + strand, within CCNA_02969 at 3126.537 kb on + strand, within CCNA_02969 at 3126.585 kb on + strand at 3126.606 kb on - strand at 3126.629 kb on - strand at 3126.693 kb on - strand, within CCNA_02970 at 3126.710 kb on - strand, within CCNA_02970 at 3126.716 kb on - strand, within CCNA_02970 at 3126.725 kb on + strand, within CCNA_02970 at 3126.794 kb on + strand, within CCNA_02970 at 3126.820 kb on + strand, within CCNA_02970 at 3126.820 kb on + strand, within CCNA_02970 at 3126.920 kb on + strand, within CCNA_02970 at 3127.075 kb on + strand at 3127.092 kb on + strand at 3127.102 kb on - strand at 3127.123 kb on - strand at 3127.194 kb on - strand, within CCNA_02971 at 3127.215 kb on - strand, within CCNA_02971 at 3127.222 kb on - strand, within CCNA_02971 at 3127.233 kb on + strand, within CCNA_02971 at 3127.336 kb on + strand, within CCNA_02971 at 3127.336 kb on + strand, within CCNA_02971 at 3127.336 kb on + strand, within CCNA_02971 at 3127.344 kb on - strand, within CCNA_02971 at 3127.344 kb on - strand, within CCNA_02971 at 3127.344 kb on - strand, within CCNA_02971 at 3127.344 kb on - strand, within CCNA_02971 at 3127.344 kb on - strand, within CCNA_02971 at 3127.388 kb on + strand, within CCNA_02971 at 3127.391 kb on - strand, within CCNA_02971 at 3127.404 kb on + strand, within CCNA_02971 at 3127.404 kb on + strand, within CCNA_02971 at 3127.404 kb on + strand, within CCNA_02971 at 3127.404 kb on + strand, within CCNA_02971 at 3127.404 kb on + strand, within CCNA_02971 at 3127.412 kb on - strand, within CCNA_02971 at 3127.412 kb on - strand, within CCNA_02971 at 3127.412 kb on - strand, within CCNA_02971 at 3127.412 kb on - strand, within CCNA_02971 at 3127.412 kb on - strand, within CCNA_02971 at 3127.412 kb on - strand, within CCNA_02971 at 3127.429 kb on + strand, within CCNA_02971 at 3127.429 kb on - strand, within CCNA_02971 at 3127.429 kb on - strand, within CCNA_02971 at 3127.429 kb on - strand, within CCNA_02971 at 3127.434 kb on + strand, within CCNA_02971 at 3127.434 kb on + strand, within CCNA_02971 at 3127.442 kb on - strand, within CCNA_02971 at 3127.453 kb on + strand, within CCNA_02971 at 3127.455 kb on - strand, within CCNA_02971 at 3127.461 kb on - strand, within CCNA_02971 at 3127.535 kb on + strand, within CCNA_02971 at 3127.538 kb on - strand, within CCNA_02971 at 3127.573 kb on - strand, within CCNA_02971 at 3127.578 kb on - strand, within CCNA_02971 at 3127.594 kb on + strand, within CCNA_02971 at 3127.599 kb on + strand, within CCNA_02971 at 3127.599 kb on + strand, within CCNA_02971
Per-strain Table
Position Strand Gene LocusTag Fraction PYE with Cisplatin 0.005 mg/ml remove 3,125,067 - +0.3 3,125,074 - -1.5 3,125,081 + +0.4 3,125,081 + +2.9 3,125,083 - -1.4 3,125,089 - -2.7 3,125,150 - +0.2 3,125,153 + +0.0 3,125,171 - +0.4 3,125,195 - -1.3 3,125,244 - -0.9 3,125,326 + CCNA_03902 0.26 -0.5 3,125,328 + CCNA_03902 0.27 -1.2 3,125,334 - CCNA_03902 0.29 +0.3 3,125,334 - CCNA_03902 0.29 +0.0 3,125,351 + CCNA_03902 0.34 +0.6 3,125,351 + CCNA_03902 0.34 -1.1 3,125,351 + CCNA_03902 0.34 -1.9 3,125,351 + CCNA_03902 0.34 +0.4 3,125,352 + +0.4 3,125,359 - CCNA_03902 0.36 -0.0 3,125,397 + CCNA_03902 0.47 +0.2 3,125,408 + CCNA_03902 0.51 +0.1 3,125,433 + CCNA_03902 0.58 +0.2 3,125,448 + CCNA_03902 0.62 +0.0 3,125,451 - CCNA_03902 0.63 -1.1 3,125,451 - CCNA_03902 0.63 -0.6 3,125,521 - CCNA_03902 0.84 +1.5 3,125,523 + CCNA_03902 0.85 -0.9 3,125,524 - CCNA_03902 0.85 +0.1 3,125,539 + CCNA_03902 0.90 -1.7 3,125,544 + -0.5 3,125,558 + +0.9 3,125,607 + +1.2 3,125,648 + CCNA_03883 0.19 -0.5 3,125,668 - CCNA_03883 0.24 -2.8 3,125,668 - CCNA_03883 0.24 +1.1 3,125,760 + CCNA_03883 0.46 -2.3 3,125,775 + CCNA_03883 0.49 +0.3 3,125,823 - CCNA_03883 0.61 -1.6 3,125,845 + CCNA_03883 0.66 -1.9 3,125,848 - CCNA_03883 0.67 +0.4 3,125,853 - CCNA_03883 0.68 -0.6 3,125,853 - CCNA_03883 0.68 +0.9 3,125,880 + CCNA_03883 0.74 -0.0 3,125,893 + CCNA_03883 0.77 -1.3 3,125,898 + CCNA_03883 0.79 +0.1 3,125,906 - CCNA_03883 0.81 +1.5 3,125,939 + CCNA_03883 0.88 +2.5 3,125,939 + CCNA_03883 0.88 -1.4 3,125,939 + CCNA_03883 0.88 -0.4 3,125,939 + CCNA_03883 0.88 -0.4 3,125,939 + CCNA_03883 0.88 +1.5 3,125,939 + CCNA_03883 0.88 -0.3 3,125,939 + CCNA_03883 0.88 +0.2 3,125,939 + CCNA_03883 0.88 +0.9 3,125,939 + CCNA_03883 0.88 -1.2 3,125,947 - -1.5 3,125,947 - -2.5 3,125,947 - -0.9 3,125,947 - +2.3 3,125,947 - -0.4 3,126,052 + -0.8 3,126,100 + +1.2 3,126,121 + CCNA_02969 0.12 +0.7 3,126,129 - CCNA_02969 0.13 -1.5 3,126,186 + CCNA_02969 0.24 +0.2 3,126,204 + CCNA_02969 0.27 +0.4 3,126,211 + CCNA_02969 0.28 +1.7 3,126,211 + CCNA_02969 0.28 +0.9 3,126,216 + CCNA_02969 0.29 +0.8 3,126,226 + CCNA_02969 0.31 +1.1 3,126,258 + CCNA_02969 0.37 +0.7 3,126,301 + CCNA_02969 0.44 +1.2 3,126,309 + CCNA_02969 0.46 +0.8 3,126,323 - CCNA_02969 0.48 -0.3 3,126,397 + CCNA_02969 0.62 +1.4 3,126,430 + CCNA_02969 0.68 +1.1 3,126,449 + CCNA_02969 0.71 +1.5 3,126,502 + CCNA_02969 0.81 +2.5 3,126,509 + CCNA_02969 0.82 +1.8 3,126,509 + CCNA_02969 0.82 +1.1 3,126,509 + CCNA_02969 0.82 +1.2 3,126,509 + CCNA_02969 0.82 -0.1 3,126,527 + CCNA_02969 0.85 +0.7 3,126,536 + CCNA_02969 0.87 -1.3 3,126,537 + CCNA_02969 0.87 +1.2 3,126,585 + -0.5 3,126,606 - -0.7 3,126,629 - -0.2 3,126,693 - CCNA_02970 0.11 +0.9 3,126,710 - CCNA_02970 0.16 +1.2 3,126,716 - CCNA_02970 0.17 +0.3 3,126,725 + CCNA_02970 0.20 +0.8 3,126,794 + CCNA_02970 0.38 +0.4 3,126,820 + CCNA_02970 0.45 +0.4 3,126,820 + CCNA_02970 0.45 +0.0 3,126,920 + CCNA_02970 0.72 +0.2 3,127,075 + -0.1 3,127,092 + -0.8 3,127,102 - +0.5 3,127,123 - +0.9 3,127,194 - CCNA_02971 0.16 +0.4 3,127,215 - CCNA_02971 0.18 +0.4 3,127,222 - CCNA_02971 0.19 +1.2 3,127,233 + CCNA_02971 0.20 -1.7 3,127,336 + CCNA_02971 0.30 +0.8 3,127,336 + CCNA_02971 0.30 +0.3 3,127,336 + CCNA_02971 0.30 -0.4 3,127,344 - CCNA_02971 0.31 +0.1 3,127,344 - CCNA_02971 0.31 +0.6 3,127,344 - CCNA_02971 0.31 +0.6 3,127,344 - CCNA_02971 0.31 +0.8 3,127,344 - CCNA_02971 0.31 +0.1 3,127,388 + CCNA_02971 0.35 -1.7 3,127,391 - CCNA_02971 0.36 +0.6 3,127,404 + CCNA_02971 0.37 +1.1 3,127,404 + CCNA_02971 0.37 -1.5 3,127,404 + CCNA_02971 0.37 -2.2 3,127,404 + CCNA_02971 0.37 -0.9 3,127,404 + CCNA_02971 0.37 -1.3 3,127,412 - CCNA_02971 0.38 +0.5 3,127,412 - CCNA_02971 0.38 +1.0 3,127,412 - CCNA_02971 0.38 -0.9 3,127,412 - CCNA_02971 0.38 +0.5 3,127,412 - CCNA_02971 0.38 -0.1 3,127,412 - CCNA_02971 0.38 -0.3 3,127,429 + CCNA_02971 0.39 -0.4 3,127,429 - CCNA_02971 0.39 +0.5 3,127,429 - CCNA_02971 0.39 +0.7 3,127,429 - CCNA_02971 0.39 +0.3 3,127,434 + CCNA_02971 0.40 -1.3 3,127,434 + CCNA_02971 0.40 -1.6 3,127,442 - CCNA_02971 0.41 -0.3 3,127,453 + CCNA_02971 0.42 -1.9 3,127,455 - CCNA_02971 0.42 -0.3 3,127,461 - CCNA_02971 0.42 +0.8 3,127,535 + CCNA_02971 0.50 -2.1 3,127,538 - CCNA_02971 0.50 +2.7 3,127,573 - CCNA_02971 0.53 +0.5 3,127,578 - CCNA_02971 0.54 +1.3 3,127,594 + CCNA_02971 0.55 -0.8 3,127,599 + CCNA_02971 0.56 -1.0 3,127,599 + CCNA_02971 0.56 -0.2
Or see this region's nucleotide sequence